The Charter Dialogue between Courts and Legislatures (Or Perhaps the Charter of Rights Isn\u27t Such a Bad Thing after All)

This article responds to the argument that judicial review of legislation under the Canadian Charter of Rights and Freedoms is illegitimate because it is undemocratic. The authors show that Charter cases nearly always can be, and often are, followed by new legislation that still accomplishes the same objectives as the legislation that was struck down. The effect of the Charter is rarely to block a legislative objective, but rather to influence the design of implementing legislation. Charter cases cause a public debate in which Charter-protected rights have a more prominent role than they would have if there had been no judicial decision. The process is best regarded as a dialogue between courts and legislatures

A Description of an Improved Homodyne Laser Interferometer

First appearing on the commercial market in the mid 1980’s, diode-pumped, continuous-wave (cw) Nd:YAG lasers have more recently been used to obtain visible output, by the incorporation of frequency doubling optics in the laser cavity.The laser diode pumping of a Nd:YAG laser rod is selective and highly efficient, resulting in compact, high power, spatial mode lasers. Frequency-doubling processes are non-linear and lead to doubling TEM00 only of the high energy fundamental temporal mode, resulting in operation of the 532 nm laser in a single spatial and single longitudinal mode. The technology is rapidly advancing, and green lasers with energies of up to 1W could soon be available. The beam properties of the lasers described above are highly desirable in the field of interferometry, where such lasers are now in direct competition with the much larger Argon lasers, which have already been employed in high power interferometric systems. We describe here the performance of a modified Michelson interferometer [1–4], built to incorporate a 90 mW ADLAS 300 diode-pumped Nd:YAG laser. In previous versions of the Michelson interferometer, we have used HeNe lasers with a few milliwatts output, requiring mirror-quality surfaces on our samples. A 90 mW laser power enables us to make displacement measurements on metal surfaces with little or no preparation. The laser could also, of course, be used in other, more elaborate interferometer types, such as the confocal Fabry-Perot, which are better suited to industrial environments

A fully integrated multi-channel detector for electron spectroscopy

In electron spectroscopy, multi-channel detection combined with intense radiation sources provides the optimum experimental configuration. Building on the 5 mm, 192-channel ion detector developed at Aberystwyth, longer arrays have been fabricated for the detection of electrons in a commercial hemispherical analyser. The performance and reliability of a 10 mm, 384-detector array is discussed and the first array-detected photoelectron spectroscopy data for single-crystal diamond are presented. In scanning mode, the detector shows a large improvement compared to single channeltron detection and this improvement allows data to be collected in snapshot mode (1 s per spectrum) to enable real-time measurements. © 2005 Elsevier B.V. All rights reserved

‘Our voice started off as a whisper and now it is a great big roar’ : The Salford Dementia Associate Panel as a model of involvement in research activities

This paper presents the work of the ‘Salford Dementia Associate Panel’, based at the Salford Institute for Dementia, Salford University (UK). We discuss the roles of the Dementia Associates, in particular around the areas of engagement and research. The panel is made up of people living with dementia, and current and former care partners. It highlights the development of this group over a four-year period and demonstrates over time how the role of a Dementia Associate member has evolved. The panel is involved in research, education and public engagement activities conducted by staff and students within the Institute. The motivations for becoming involved are clearly articulated and demonstrate how the personal backgrounds of individuals have driven the collective involvement and desire to bring about change. The benefits and challenges associated with working as part of a panel are discussed. We conclude by bringing together our experiences as a set of suggestions for others who may wish to create a similar forum to promote the involvement of people living with dementia and former and current care partners

Exploring Pharmacists’ Roles during the 2019–2020 Australian Black Summer Bushfires

Background: Australians are no strangers to sudden natural disasters, such as bushfires. The effects of a natural disaster can devastate local communities and health care services. Currently, limited research has explored the role of the pharmacist during a natural disaster. This study explores the role of the Australian pharmacist during the 2019/2020 Black Summer Bushfires. Methods: Semi-structured phone interviews were conducted with ten community pharmacists who worked through the Black Summer Bushfires whose daily tasks and work environment were directly affected by the bushfires. Thematic analysis using NVivo®, a qualitative data analysis software was conducted. Results: Analysis of the transcripts generated six main themes: collaboration; trauma and mental health; power and communication; acute presentations; triaging and emergency prescribing. Pharmacists worked in close collaboration with doctors and members of the local community. They provided triaging services, timely health advice about chronic health problems, and managed acute issues, including wound and burn management and mental health support in traumatic conditions, sometimes without power and communication amenities. The challenges presented to pharmacists during the bushfires warranted creative and flexible approaches at times. Conclusion: This study highlights the need for mental health support and training for pharmacists, provisional prescribing privileges, and a clearer set of contingency regulations and legislation related to emergencies and natural disasters. Further research is warranted to gain greater insight into the roles undertaken by Australian pharmacists during natural disasters and their autonomy in decision making processes during such times

Women on boards : the role of social capital and networking in corporate board director selection processes

There remains a paucity of women in both executive and non-executive director roles in British boardrooms. This research explores how far this is explained by differences in levels of social capital and networking activities between men and women seeking boardroom positions. While it is known that social capital is important at junior and middle management levels (with existing research showing that the quality of men’s and women’s networks differ, and that women are not able to leverage their networks to the same extent as their male colleagues) no rigorous academic research on this issue has been conducted specifically at corporate board level, largely due to the difficulty of securing access to respondents. This thesis addresses the gap in the literature by drawing on data gathered from 82 semistructured interviews with Chairs, head-hunters and aspiring or recently appointed male and female directors. The research questions asked: what is the role of social capital and networking in corporate board selection processes; how far can Human Capital Theory, Preference Theory, Attribution Theory and Self-Efficacy explain the lack of progress of senior women to board level roles?; do aspiring female directors have poorer quality networks and less social capital than their male peers; why might this be; and are female aspiring directors as willing and able to leverage their social capital as their male peers. The findings affirm the importance of social capital theory in relation to selection to boardroom roles. Preference Theory, Human Capital Theory and Attribution Theory and Self-Efficacy are not found to explain the lack of promotion of senior female executives to board director positions. Other key contributions include insights into board director selection processes, the effectiveness of regulatory and voluntary codes, and gender differences in networking and job seeking activities of aspiring directors

A gastrin transcript expressed in gastrointestinal cancer cells contains an internal ribosome entry site

As the hormone gastrin promotes gastrointestinal (GI) cancer progression by triggering survival pathways, regulation of gastrin expression at the translational level was explored. Sequence within the 5′ untranslated region of a gastrin transcript expressed in GI cancer cells was investigated, then cloned into a bicistronic vector upstream of firefly luciferase and transfected into a series of GI cancer cell lines. Firefly luciferase activity was measured relative to that of a cap-dependent Renilla luciferase. A gastrin transcript that was different from that described in Ensembl was expressed in GI cancer cells. Its transcription appears to be initiated within the region designated as the gene's first intron. In GI cancer cells transfected with the bicistronic construct, firefly luciferase activity increased 8–15-fold compared with the control vector, and there was a further induction of the signal (up to 25-fold) following exposure of the cells to genotoxic stress or hypoxia, suggesting that the sequence acts as an internal ribosome entry site. These data suggest that the gastrin transcript within GI cancer cells contains an internal ribosome entry site that may allow continued expression of gastrin peptides when normal translational mechanisms are inactive, such as in hypoxia, thereby promoting cancer cell survival