富血小板衍生物在口腔医学中的研究与应用

富血小板衍生物是将全血进行离心后得到的富血小板的物质,富含各种生长因子,可以促进骨组织和软组织的修复和再生。本文主要探讨富血小板衍生物在口腔医学领域的研究及应用现状

Practices on Cultural Construction in Experimental Chemistry Demonstration Center

根据国家级厦门大学化学实验教学示范中心的建设特点,从实验室环境文化、制度文化、管理文化和精神文化多个方面入手建设实验室文化的实践进行总结与分享。This paper summarized our practices on cultural construction in chemistry laboratory including laboratory environment, rules, management and spirit based on the characteristics of our center.国家基础科学人才培养基金(J1210014);; 2016年度教育部“基础学科拔尖学生培养试验计划”研究课题;; 福建省高等学校教学改革研究项目(JAS14634

如何精准做好化学教学实验室的建设

主要介绍了厦门大学化学国家级实验教学示范中心在实验室细化建设方面的具体做法,如实验室的给排水、供配电、通风等系统工程和实验家具的精准设计和精准施工,以期更好地为国内高校化学教学实验室的细化设计和细化建设提供适应面广、操作性强的可借鉴经验。2016年度教育部“基础学科拔尖学生培养试验计划”研究课题;;2017年福建省本科高校教育教学改革研究项目(FBJG20170295);;2017年度厦门大学教学改革研究项目(JG20170204);;国家基础科学人才培养基金项目(J1310024

以1-苯基-3-甲基-4-苯甲酰基代吡唑酮[5]萃取稀土和钍铀钛锆及其在分析化学中的某些应用

本文研究了以PMBP-苯萃取稀土和钍、铀、钛、锆的萃取行为。测定了La、Ce、Pr、Nd、Sm、Gd、Dy、Yb、Y、U(Ⅵ)、Ti、Th和Zr的pH_(1/2)值,计算了它们的萃取平衡常数。并介绍了近十年来作者将此萃取剂应用于铀、钍、稀土、鋰、钢铁合金及岩石中痕量稀土、钍和钙的分离和测定方面的工作。实践证明,PMOP合成简便、价格低廉、萃取能力较强,是比TTA更为优越的萃取剂

钙离子对亚麻籽胶-紫苏分离蛋白负载DHA藻油 乳液储藏特性与递送虾青素效果的影响Effect of calcium ions on storage properties and astaxanthin delivery efficiency of DHA algae oil-loaded emulsion using flaxseed gum-perilla protein isolate

DHA藻油是补充ω-3多不饱和脂肪酸的重要非动物来源，但因其自身水溶性差、易氧化产生不良风味等特点，极大约束了其摄入途径。据此，采用高压微射流技术与逐层沉积技术（LBL）制备负载DHA的亚麻籽胶（FG，质量分数为0.4%）-紫苏分离蛋白（PPI，质量分数为0.225%）双层乳液，研究Ca2+添加量（0%～0.5%）对上述双层乳液体系稳定性的影响；同时，采用INFOGEST体外模拟消化模型，探究PPI-DHA藻油单层乳液、FG-PPI-DHA藻油双层乳液、Ca2+-FG-PPI-DHA藻油双层乳液中DHA的消化特性，以及上述3种体系递送虾青素的效率，并通过监测其在消化过程中粒径分布、电荷特性及微观状态变化等解释其内在机理。结果表明：DHA藻油双层乳液储藏20 d后，未添加Ca2+的双层乳液的粒径从10.4 μm降低至4.3 μm，Zeta-电位从-23 mV降低至-33 mV，Ca2+添加量为0.4%的双层乳液的粒径和电位未发生显著变化，乳液液滴分布均匀，无分层、絮凝、沉淀现象；DHA藻油双层乳液储藏20 d后，添加Ca2+的双层乳液的Turbiscan抗重力稳定性指数（TSI）较未添加Ca2+的双层乳液有明显改善；3种乳液体系模拟消化过程中，游离脂肪酸释放量分别为68.88%、50.84%、52.32%，虾青素生物可及性分别为47.42%、12.54%、966%。说明添加Ca2+有利于DHA藻油双层乳液的稳定储藏，但对消化过程中脂肪酸与虾青素的释放具有一定迟缓效果，研究结果可为设计靶向递送体系提供重要理论依据。DHA algae oil is an important non-animal source for supplementing omega-3 polyunsaturated fatty acids (ω-3 PUFA), but due to its poor water solubility and easy oxidation to produce bad flavor, its intake route is greatly restricted. Accordingly, high-pressure micro-jet technology and layer by layer (LBL) were used to prepare DHA-loaded flaxseed gum (FG, mass fraction 0.4%)-perilla protein isolate (PPI, mass fraction 0.225%) double-layer emulsion, focusing on the effect of calcium ion addition (0%-0.5%) on the stability of the above-mentioned double-layer emulsion system. At the same time, the INFOGEST in vitro simulated digestion model was used to explore the digestion characteristics of DHA in PPI -DHA algae oil single-layer emulsion, FG-PPI -DHA algae oil double-layer emulsion, and Ca2+-FG-PPI -DHA algae oil double-layer emulsion, as well as the efficiency of astaxanthin delivery by the above three systems, and its internal mechanism was explained by monitoring its particle size distribution, charge characteristics and microscopic state changes during the digestion process. The results showed that after 20 d storage of the DHA algae oil double-layer emulsion, the particle size and Zeta-potential of the double-layer emulsion without Ca2+ decreased from 10.4 μm to 4.3 μm, from -23 mV to -33 mV, respectively, but for the double-layer emulsion with 0.4% Ca2+ addition，the particle size and Zeta-potential did not change significantly, the emulsion droplets were evenly distributed, and there was no delamination, flocculation, or sedimentation.After 20 d storage of the DHA algae oil double-layer emulsion, the Turbiscan anti-gravity stability index (TSI) of the Ca2+-added double-layer emulsion was significantly improved compared with the non-Ca2+-added double-layer emulsion. During the simulated digestion process of the three emulsion systems, the release of free fatty acids in the three systems was 68.88%, 50.84% and 52.32% respectively, and the bioavailability of astaxanthin in the simulated digestion process was 47.42%, 1254% and 9.66%, respectively. It shows that the addition of Ca2+ is beneficial to the stable storage of the DHA algae oil double-layer emulsion, but has a certain retarding effect on the release of fatty acids and astaxanthin during the digestion. The research results provide an important theoretical basis for designing a targeted delivery system