Evaluation of the effect of nutritional status in patients with cancer receiving chemotherapy on anthropometric measurements and quality of life

The aim of this study is to determine the nutritional status, anthropometric measurements and quality of life of adult patients with cancer receiving chemotherapy, and to evaluate their interactions. In this retrospective cross sectional study, information about the patients’ demographic characteristics, anthropometric measurements, nutritional status, hand grip strengths which were measured with a portable digital hand dynamometer, and the quality of life scores were obtained from the patient files. According to NRS-2002, 16.3% of the patients were at the risk of malnutrition. The body weight, body mass index, waist circumference, hip circumference, mid-upper arm circumference, hand grip strength values of the individuals who had three or higher scores from NRS-2002 were significantly lower (p < 0.05). Considering the evaluation of the quality of life scores based on their nutritional status, the functional and general health score was significantly lower in patients at the risk of malnutrition and their symptom score was significantly higher (p < 0.05). The presence of nutritional risk in cancer patients is related to the quality of life. In conclusion, the nutritional status of patients with cancer should be evaluated regularly, and early intervention regarding this is important to increase the quality of life.No sponso

Gastric gastrointestinal stromal tumor with bone metastases - Case report and review of the literature

Gastrointestinal stromal tumors (GISTs) represent rather rare neoplasms. Most GISTs are benign; malignant tumors account for 20-30% of cases (overall, approximately 10-30% of GISTs exhibit malignant behavior). GISTs most commonly metastasize to the liver and abdominal cavity. Distant metastases to other sites, especially to the bones, are relatively rare. We report a case of a 62-year-old man with metastatic spread of GIST to skull, ribs and both sacroiliac joints manifesting six months after surgical resection of a gastric tumor. Although bone metastases from GISTs are rare and there are only a few reported cases in the literature, this case emphasizes that metastatic disease should always be considered in a patient with gastric GIST and suspicious bone lesions

Polycyclic Aromatic Hydrocarbons (PAHs) and Their Importance in Animal Nutrition

Polycyclic aromatic hydrocarbons (PAHs) formed as a result of incomplete combustion of organic compounds. It contains compounds that cause toxic, teratogenic, mutagenic and carcinogenic damage, such as heterocyclic aromatic amines, benzene and formaldehyde. PAHs can be found in industrial wastes, garbage, cigarette smoke, pesticides and flue gases and can contaminate air, water, soil and food. Although more than 100 PAH compounds are detected in nature, it is accepted that 16 PAH compounds have more harmful effects. It is important to determine the PAH exposure levels of feeds used in animal nutrition, since the contamination of feed plants and factory feeds with PAH compounds will indirectly affect human health. In this study, the physical and chemical properties of PAHs and their effects on animal production and indirectly on human health were compiled

Bıldırcın rasyonlarına propiyotik ve humik asitin yalnız ve kombine katılmasının besi performansı ve karkas kalitesine etkisi

This experiment was carried out to determine the both single and combined effects of humates (Farmagulator XPTM) andprobiotics (BiosaccTM) in quail diets on fattening performance and carcass yields. A total of 300 one-day old Japanese Quails(Coturnix coturnix japonica) were used in this experiment. Animals were divided into one control group and three treatmentgroups containing 75 birds each. Each group was further divided into three replicates containing 25 birds each. The experimental period lasted for 35 days. The control group was fed with unsupplemented basal diets. The rations of treatment groups weresupplemented with 1 g/kg Farmagulator XPTM (Group H), 0.5 g/kg BiosaccTM (Group B) and 1 g/kg Farmagulator XPTM + 0.5 g/kg BiosaccTM combination (Group H+B), respectively. At the end of the study there were no statistically signifi cant differences among the groups in terms of body weight gain, feed consumption, feed conversion ratio and carcass yield (P&gt;0.05). But, bodyweight scores were found higher at the 4th and 5th weeks in the group H (P&lt;0.05). It is concluded that the use of probiotic andhumic acid alone and combination has no additional effect on quail performance.Bu araştırma, bıldırcın rasyonlarına ilave edilen humik asid (Farmagulator XP™) ve probiyotik (Biosacc™)’ın, yalnız veya kombine kullanımının besi performansı ve karkas kalitesine etkilerini belirlemek amacıyla yapılmıştır. Araştırmada toplam 300 adet günlük Japon bıldırcın (Coturnix coturnix japonica) civcivi kullanılmıştır. Her grupta 75 civciv bulunan bir kontrol ve 3 deneme grubu oluşturulmuştur. Gruplar kendi aralarında 3’erli alt gruba ayrılmıştır. Deneme beş hafta sürdürülmüştür. Kontrol grubu basal rasyonla beslenmiştir. Deneme grubu rasyonlarına sırasıyla 1 g/kg Farmagulator XP™ (Grup H), 0.5 g/kg Biosacc™ (Grup B) ve 1 g/kg Farmagulator XP™ + 0.5 g/kg Biosacc™ (Grup H+B) kombinasyonu ilave edilmiştir. Araştırma sonunda, canlı ağırlık artışı, yem tüketimi, yemden yararlanma oranı ve karkas verimleri bakımından istatistik açıdan önemli bir fark görülmemiştir (P>0.05). Bununla beraber canlı ağırlık değişimleri 4 ve 5. haftalarda Grup H’ de daha yüksek bulunmuştur (P<0.05). Sonuç olarak, probiyotik ile humik asitin yalnız ve birlikte kullanılmasının performansta ilave bir artışa yol açmadığı görülmüştür

Mediastinal Ectopic Parathyroid Adenoma in a Patient Followed for Colon Cancer and Chronic Renal Failure: A Challenging Case

Colorectal cancer is a significant cause of morbidity and mortality worldwide. The advances in early diagnosis and treatment have increasingly expanded the patient population surviving from colorectal cancer. Herein, we present a case of a patient with mediastinal ectopic parathyroid adenoma who has been followed up for postoperative colon cancer. The patient is a 59-year-old man with postoperative colon cancer and chronic renal failure in whom control positron emission tomography/computed tomography revealed multiple bone metastases. However, on methylenediphosphonate bone scintigraphy, multiple involvement with increased uptake was associated with renal osteodystrophy/hyperparathyroidism; technetium-99m 2-methoxyisobutylisonitrile parathyroid scintigraphy was performed, which revealed mediastinal ectopic parathyroid adenoma. To the best of our knowledge, this is the first case report in the literature reporting the co-occurrence of colon cancer, chronic renal failure, and ectopic parathyroid adenoma

İçme suyuna farklı düzeylerde ilave edilen esansiyel yağ karışımının (nane-kekik-anason yağı) bıldırcınlarda büyüme performansı, Karkas parametreleri ve ileumun histolojik yapısı üzerine etkileri

Bu araştırma, bıldırcın içme suyuna oregofarm (nane-kekik-anason yağı) ilavesinin büyüme ve besi performansı, karkas özellikleri ve ileumun histolojik yapısı üzerine etkisini belirlemek amacıyla yapılmıştır. Araştırmada her iki cinsiyette toplam 348 adet Japon bıldırcın (Coturnix coturnix japonica) civcivi kullanılmıştır. Her grupta 116 civciv bulunan 1 kontrol 2 deneme grubu oluşturulmuştur. Gruplar kendi aralarında 4'erli alt gruba ayrılmıştır ve her alt grup 29 adet civcivden oluşturulmuştur. Deneme altı hafta sürdürülmüştür. Bütün deneme grupları temel rasyonla beslenmiştir ve deneme boyunca temiz içme suyu sağlanmıştır. Kontrol grubunun içme suyuna oregofarm ilavesi yapılmamıştır. 1. deneme grubu ve 2. deneme grubu içme suyuna sırasıyla 1.0 mg/5 L ve 1.5 mg/5 L. oregofarm ilavesi yapılmıştır. Tüm deneme gruplarına yem ve su ad-libitum olarak verilmiştir. Araştırma sonunda, yem tüketimi ve yemden yararlanma oranı bakımından 3. haftada istatistiksel açıdan önemli farklılıklar (P0.05). Denemenin sonunda gruplar arasında sıcak ve soğuk karkas parametreleri bakımından istatistiksel olarak farklılıklar bulunmuştur (P0.05). Sonuç olarak, bıldırcın içme suyuna oregofarm ilavesinin performansı artırıcı ilave bir etkisinin olmadığı tespit edilmiştir.This study was conducted in order to define the effects of oregofarm (peppermint, thyme and anise oil) supplementation in the drinking water on the growth performance, carcass quality and histologic structure of terminal ileum in quails. A total of 348 Japanese quail chicks (Coturnix coturnix japonica) of both sexes were included in this study. They were divided into one control group and two experimental groups and each of them contained 116 Japanese quail chicks. Each group was further divided into four subgroups with 29 Japanese quail chicks. This study was finalized in six weeks. All groups were fed with basal diets and received fresh water during the experiment. The control group received non-supplemented water. The group 1 and 2 received 1.0 ml/5 L and 1.5 ml/5 L oil mixture, respectively. All experimental groups were fed with water and ad-libitum. As a result of the study, there were statistically significant differences between the feed consumption and efficiency (P&lt;0.001) in the end of the three weeks. Similarly, there were also statistically significant differences between same parameters (P&lt;0.01; 0.05) five weeks later. The body weights of quails were not significantly different from each other (P&gt;0.05). At the end of the study, there were statistically differences in the warm and cold carcass parameters (P&lt;0.05). Adding essential oil mixed were not affected on histological structure of terminal ileum (P&gt;0.05). Conclusively, the supplementation of oregofarm (peppermint + thyme and anise oil) has no additional effect on quail performance

The effects of grazing and concentrate supplementation at pasture on performance and rumen parameters in lambs

Bu çalışmada, kuzuları merada otlatma ve meraya ilave konsantre yem verilmesinin besi performansı, rumen pH, toplam uçucu yağ asitleri ve amonyak azotu üzerine etkisi araştırılmıştır. Ayrıca, vejetasyon dönemine bağlı olarak meranın besin madde içerikleri de belirlenmiştir. Araştırmada sütten kesilmiş 2-3 aylık yaşta, 18 baş Tuj ırkı erkek kuzu kullanılmıştır. Araştırmada kuzular 6 başlı üç gruba ayrılmıştır. Meraya ilave olarak kuzulara %18.5 HP ve 2.650 kcal/kg ME içeren konsantre yem verilmiştir. Kuzulardan 6 başı yalnız merada otlatılmış (Mera Grubu), 6 tanesine meraya ilave olarak kuzu başına 200 g konsantre yem (Mera + Ek Yem Grubu I) ve 6 baş kuzuya da meraya ek olarak 400 g konsantre yem (Mera + Ek Yem Grubu II) verilmiştir. Kuzular, günde 8 saat süreyle merada otlatılmıştır. Ek yemler merada otlatma sonrası verilmiş ve kuzuların günde iki defa su içmeleri sağlanmıştır. Hayvanlar ayda bir tartılarak canlı ağırlık artışları belirlenmiştir. Araştırma 3 ay sürdürülmüştür. Merada otlatma ve ilave konsantre yem verilmesi, kuzuların canlı ağırlıklarında bir fark oluşturmamıştır (P>0.05). Günlük canlı ağırlık artışı merada otlayan, meraya ilave 200 g ve 400 g konsantre yem verilen kuzularda sırasıyla günde 153, 161 ve 183 g olarak belirlenmiştir. Merada otlatma ve ilave konsantre yem verilmesinin kuzuların rumen sıvısı pH, TUYA ve NH3-N değerlerinde herhangi bir farklılık oluşturmadığı saptanmıştır (P>0.05). Meranın KM ve HS içeriği vejetasyonun ilerlemesiyle atarken (%31.33-74.89, %29.08-34.68), HP içeriği ise %11.01’den %6.25’e inmiştir (P<0.05). Sonuç olarak, meraya ilave konsantre yem verilmesinin kuzularda performans ve rumen parametrelerinde bir farklılık oluşturmadığı saptanmıştır. Meranın besin madde içeriğinde ise vejetasyona bağlı olarak önemli değişikliklerin olduğu belirlenmiştir.In this study, the effect of grazing and concentrate supplementation on fattening performance, rumen pH, total volatile fatty acids and ammonia nitrogen concentration in lambs were investigated. The effect of vegetation period on nutrient content of the pasture were also determined. Eighteen Tushin lambs, 2-3 months age and weaned were used in experiment. Lambs were divided into three groups with their weight and each group consists of 6 lambs. Concentrate with 18.5% CP and 2.650 kcal/kg ME was fed to lambs in addition to pasture. Six lambs were only grazed (Pasture Group). Six lambs were supplemented 200 g concentrate with the pasture (Pasture + Suppl. I Group) and six lambs were supplemented 400 g concentrate with the pasture (Pasture + Suppl. II Group). Lambs were grazing on the pasture 8 h in a day. Supplementated feeds were given after the grazing and water was supplied two times in a day. The lamb body weight gains were determined monthly. The experiment was lasted three month.s There were no significant effect of grazing and supplementation on body weight of lambs (P&gt;0.05). Daily weight gain of grazing and supplementation groups were determined 153, 161, 183 g respectively. There were no significant differences in rumen fluid pH, TVFA and NH3-N between the grazing or supplementation groups (P&gt;0.05). Dry matter and CF contents of pasture were increased with respect to the vegetation period (31.33-74.89%, 29.08-34.68%), but CP was decreased from 11.01% to 6.25% (P&lt;0.05). As a result, supplementation of concentrate feed to grazing lambs on the pasture were no effect on performance and rumen parameters in lambs. On the other hand there were differences nutrient contents of pasture with vegetation

Changes in serum biochemical and lipid profile, and fatty acid composition of breast meat of broiler chickens fed supplemental grape seed extract

A study was conducted to evaluate the changes in serum biochemical and lipid profile, and fatty acid composition of breast meat of broiler chickens fed supplemental grape seed extract (GSE). A total of 240 1-day-old male broiler chickens were randomly allocated to 4 groups, each consisting of 4 replicate pens having 15 birds/replicate pen. One group served as control group fed basal diets and other groups received 100, 200, and 400 ppm GSE supplemented to the basal diets. Liver weight was greater in broilers fed 200 ppm GSE compared to the other groups (P = 0.004, L = 0.024, C = 0.010). Serum AST and ALT levels decreased (P < 0.001) whereas ALP levels increased with increasing dietary GSE levels (P < 0.001). Serum albumin and total protein levels were lower in control in comparison with other groups (P < 0.001). Serum cholesterol, triglyceride, and LDL levels declined (P < 0.001) while HDL levels increased with increasing supplemental GSE levels (P < 0.001). MUFA levels were greater in breast meat of broiler chickens fed diets supplemented with 100 ppm GSE. On the other hand, PUFA (including n-3 and n-6) were greater in broiler chickens fed control diets or 400 ppm GSE supplemented diets. In general, essential fatty acids such as alpha-linolenic acid (n-3 C18:3), arachidonic acid (n-6 C20:4), eicosapentaenoic acid (n-3 C20:5), and docosahexaenoic acid (n-3 C22:6) were greater in breast meat of broiler chickens fed supplemental GSE (100, 200, or 400 ppm) while overall UFA concentration in breast meat remained unaffected. In conclusion, findings of this study suggest that dietary supplementation of up to 400 ppm GSE in broilers may improve serum biochemical and lipid profile. It may also improve the fatty acid composition of breast meat to varying extent despite no effect on overall UFA concentration

Emmer wheat (Triticum dicoccum)-based intervention in Japanese quail's diet and its impact on performance, carcass yield, meat fatty acids, and fecal volatile fatty acids

The high nutritional and nutraceutical qualities of emmer wheat make it a valuable cereal grain. The present study was designed to quantify the contribution of emmer wheat inclusion into Japanese quail's rations in terms of their productive responses, alterations in the fatty acid profile of their meat, and changes in the composition of volatile fatty acids in their feces. For this purpose, a total of 160, 1-day-old Japanese quails (Coturnix coturnix japonica) were randomly allotted to four dietary treatments (4 replicates and 10 quails/replicate) with different levels of emmer wheat including 0% (control), 5% (T5), 10% (T10), and 15% (T15). These dietary treatments were administered for a period of 35 days. The results obtained from the study showed that dietary changes led by incorporation of increasing levels of emmer wheat into quail rations had no negative impact on quail's health and production. Moreover, supplemental emmer could promote better feed conversion ratio and higher carcass yield, while it did not affect the relative weights of internal organs including liver, gizzard, and heart. In addition, the incorporation of increasing levels of emmer wheat into quail rations was characterized by a reduction in total saturated and monounsaturated fatty acids, whereas an increase was observed in the levels of total unsaturated and polyunsaturated fatty acids in breast meat. Emmer wheat inclusion also increased the levels of omega-3 and omega-6 fatty acids in breast meat. Regarding volatile fatty acid profile, a lower percentage of propionic acid while a higher percentage of acetic acid were recorded in feces of quails fed emmer wheat-based diets when compared to those fed control diets. Overall, as confirmed by the present findings, the incorporation of emmer wheat into quail diets could be proposed as a valuable strategy for the promotion of animal health and performance. More research is needed to further investigate the promising roles of using emmer wheat in poultry nutrition