Postpartum Cystic Juvenile Granulosa Cell Tumor: A Case Report

Introduction: Juvenile granulosa cell tumor (JGCT) is a subtype of granulosa cell tumors of the ovary. 80% of JGCT occurs at prepubertal period. And, it is considered to be a slow growing tumor. In addition, gross appearence of it is mostly solid. Herein, we report a pure cystic JGCT case that was detected soon after childbirth with huge dimension.Presentation of Case: We report a 21 year-old woman who presented with abdominal mass during 6th month after childbirth. Ultrasound revealed a cystic mass of approximately 20 cm in diameter originated from left ovary. The patient underwent laparotomy and unruptured left ovarian cystic mass resection was performed. Uterus and right ovary were totally normal and extraovarian spread was not found. Macroscopic examination revealed totally cystic tumor of 25,5x22x10,2 cm with smooth outlines, containing serous fluid. There were papillary projections and small polypoid structures around 1 cm in diameter into the cavity. Histopathologic and immunohistochemical findings were compatible with JGCT. Relaparotomy was performed for staging and the patient was evaluated as stage IA. She is currently under clinical follow up without any further treatment.Conclusion: It should be noted that JGCT may rapidly grow and reach a higher dimension, occur during pregnancy and at postpartum period, and may present as cystic rather than a solid mass as in our case presented here

Clear Cell Meningioma: A Rare Great Mimicker

Introduction: Clear cell meningioma is an infrequent, agressive variant of meningioma that shows proclivity to the spine. This study aimed to report a case of clear cell meningioma of the lumbar spine and discuss the differential diagnosis, and emphasize the necessity and usefulness of immunohistochemistry for definite diagnosis.Case report: A 23-year-old man admitted to the Department of Neurosurgery with backache existed for about 4 years. Magnetic Resonance Imaging revealed a well-circumscribed intradural and extramedullary mass in the spinal canal at the 5th lumbar vertebra extending to the right neural foramen. The lesion was excised gross totally and diagnosed as “clear cell meningioma”. The patient has been doing well for a year without any sign of recurrence.Discussion: Clear cell meningioma should be considered in the differential diagnosis of the masses located in the spine radiologically. In addition, the histopathological mimickers of it that are composed of clear cells, particularly renal cell carcinoma, should be ruled out by the aid of immunohistochemistry

Have Skin Biopsy Results in Adults Been Affected in the COVID-19 Pandemic?

The purpose of this study was to assess how skin biopsy results from adults, which occupy an important place in dermatological practice, have been affected by the COVID-19 pandemic. Adult patients aged over 18 presenting to the dermatology clinical of a tertiary hospital between March 12, 2019 and March 11, 2020, and between March 12, 2020 and March 11, 2021, from whom skin biopsies had been taken and who had undergone pathological examination were included in the study. Pre-COVID-19 pandemic data were compared with post-pandemic data. No significant difference was determined between the two periods in terms of age, sex, type of biopsy, preliminary diagnosis numbers, or clinicopathological correlation (P>0.05). The diseases most frequently diagnosed through biopsy before the pandemic were psoriasis (13.7%), pseudopelade of Brocq (6.8%), and fibroepithelial polyp (5.5%), compared with psoriasis (9.4%), basal cell carcinoma (BCC) (6.3%), lichen planus (6.3%), and urticarial vasculitis (6.3%) during the pandemic. Diagnoses of BCC and urticarial vasculitis were significantly elevated after the COVID-19 pandemic (P<0.05), while no periodic difference was observed in other diagnoses. A rise in the incidence of various diseases, such as urticarial vasculitis, may be indicative of a risk of asymptomatic COVID-19. Further polymerase chain reaction and/or antibody-based investigations should be carried out in order to establish whether dermatological diseases are associated with asymptomatic COVID-19 cases. Determining the clinical and histopathological aspects of COVID-19, which can progress with various cutaneous findings, will be useful in the early diagnosis and treatment of this novel and life-threatening disease

Have Skin Biopsy Results in Adults Been Affected in the COVID-19 Pandemic?

The purpose of this study was to assess how skin biopsy results from adults, which occupy an important place in dermatological practice, have been affected by the COVID-19 pandemic. Adult patients aged over 18 presenting to the dermatology clinical of a tertiary hospital between March 12, 2019 and March 11, 2020, and between March 12, 2020 and March 11, 2021, from whom skin biopsies had been taken and who had undergone pathological examination were included in the study. Pre-COVID-19 pandemic data were compared with post-pandemic data. No significant difference was determined between the two periods in terms of age, sex, type of biopsy, preliminary diagnosis numbers, or clinicopathological correlation (P>0.05). The diseases most frequently diagnosed through biopsy before the pandemic were psoriasis (13.7%), pseudopelade of Brocq (6.8%), and fibroepithelial polyp (5.5%), compared with psoriasis (9.4%), basal cell carcinoma (BCC) (6.3%), lichen planus (6.3%), and urticarial vasculitis (6.3%) during the pandemic. Diagnoses of BCC and urticarial vasculitis were significantly elevated after the COVID-19 pandemic (P<0.05), while no periodic difference was observed in other diagnoses. A rise in the incidence of various diseases, such as urticarial vasculitis, may be indicative of a risk of asymptomatic COVID-19. Further polymerase chain reaction and/or antibody-based investigations should be carried out in order to establish whether dermatological diseases are associated with asymptomatic COVID-19 cases. Determining the clinical and histopathological aspects of COVID-19, which can progress with various cutaneous findings, will be useful in the early diagnosis and treatment of this novel and life-threatening disease

Adenoid Cystic Carcinoma of the Scalp as a Cause of Recurrent Operations

Introduction: Primary cutaneous adenoid cystic carcinoma (PACC) is a rare slow-growing tumor. Presentation of the case: We report a 62 year-old woman presented with a nodular lesion on the scalp who had three operations before for recurring lesion at the same localization. In the operation, we detected a lesion which was adherent to thesubcutaneous tissue. The lesion was firm and gray-white colored, and invading the surrounding soft tissues. According to histopathological findings, the patient diagnosed with adenoid cystic carcinoma.  Conclusions: Primary cutaneous adenoid cystic carcinoma is a rare tumor that the etiology, origin, and treatment are still controversial. The metastases must be ruled out from other sites, especially from the salivary glands after the its pathological diagnosis

A Patient with Severe Cervicofacial Subcutaneous Emphysema Associated with Munchausen’s Syndrome: A Case Report

Subcutaneous cervicofacial emphysema is a rare and life-threatening condition that results from various causes. In this report, we documented a case of a patient with severe subcutaneous cervicofacial emphysema a condition that falls under the umbrella of Munchausen’s syndrome and discussed the workup of this patient. Thorough diagnostic investigations seeking the etiology of the condition proved unsuccessful. When faced with cases of recurring subcutaneous cervicofacial emphysema, where the root cause remains ambiguous a diagnosis of Munchausen’s Syndrome should be considered

Triple Synchronous Tumors in a Patient: Gastric Adenocarcinoma, Omental Gastrointestinal Stromal Tumor and Renal Angiomyolipoma

Introduction: The presence of synchronous distinct tumors is uncommon in the literature, and the etiology of it is still unknown.Presentation of Case: Herein, we report a 42 year-old-woman with synchronous triple tumors of gastric adenocarcinoma, renal angiomyolipoma (AML), and omental gastrointestinal stromal tumor (GIST). She underwent total gastrectomy after the diagnosis of adenocarcinoma by endoscopic biopsy. During macroscopic examination of gastrectomy specimen, an ulcerated tumor about 4.5 cm in diameter was observed in the fundus. Histopathologically, it was diagnosed as adenocarcinoma harboring some signet-ring features. While dissecting lymph nodes of the omentum of the lesser curvature, a nodular mass about 4.2 cm in diameter seemed to be a lymph node was detected macroscopically. However, it was diagnosed as GIST by histopathological and immunohistochemical features. Also, partial nephrectomy was performed during the same session due to a mass detected radiologically in the left kidney about 2.2 cm in diameter. It was indicated to be metastatic gastric adenocarcinoma clinically but AML was determined by histopathological and immunohistochemical findings.Conclusion: To the best of our knowledge, our patient is the first case in the literature that has synchronous tumors of gastric adenocarcinoma, omental GIST and renal AML

ÇEVRESEL KUZNETS EĞRİSİ HİPOTEZİ’NİN TÜRKİYE’DE GEÇERLİLİĞİNİN TESTİ

Bu çalışmada Çevresel Kuznets Eğrisi Hipotezi’nin Türkiye’de 1967-2015 yılları arasında geçerliliği fourier temelli analizlerle test edilmiştir. Veri seti olarak ekonomik büyümeyi temsilen reel gayri safi yurt içi hasıla, çevresel bozulmayı temsilen karbon emisyonu değerleri kullanılmıştır. Analiz sonuçlarına göre ekonomik büyüme ve çevresel bozulma ilişkisinin ters U formunda olduğu Türkiye’de Kuznetz Eğrisi hipotezinin geçerli olduğu kanıtlanmıştır

Metastatic Serous Carcinoma Initially Presented As An Incarcerated And Strangulated Umbilical Hernia: A Rare Case Report

Introduction: We report a rare case of a metastatic serous ovarian carcinoma presented as an incarcerated and strangulated umbilical hernia.Presentation of case: A 54 year-old female was admitted to the hospital with a painful mass around the umblical region. It was elucidated during clinical history that the mass had been present for 3 to 4 years without pain. An incarcerated and strangulated umbilical hernia including a solid mass and mesenteric fat was detected on physical examination. She underwent an urgent operation for strangulated umbilical hernia. The pathological diagnosis of the hernia material was reported as carcinoma compatible with serous ovarian carcinoma metastasis. Concurrently, total abdominal histerectomy and bilateral salphingo-oopherectomy, pelvic and paraaortic lymph node dissection, omentectomy and sigmoid colon resection were performed. Histopathological evaluation confirmed the serous carcinoma originated from the left ovary.Conclusion: In the literature, some metastatic tumors have been reported to be presented as umbilical metastasis rarely. However, the present case is the first metastatic ovarian cancer that initially presented as an incarcerated and strangulated umbilical hernia in the literature, to the best of our knowledge. 

Steroid Cell Tumor of Ovary Diagnosed After Delivery; Case Report

Introduction: Steroid cell tumors (SCTs) constitute less than 0.1% of all ovarian tumors. They are divided into 3 categories according to cell of origin: Stromal Luteoma arising from stromal cells of the ovary, Leydig cell tumor arising from Leydig cells, and SCT not otherwise specified (NOS) when the origin of the tumor is not defined. Case Presentation: Herein is presented a case of SCT diagnosed one month after a caesarian section delivery of a female fetus with ambiguous genitalia. The patient was admitted to the emergency department with the findings of acute abdomen, and surgery was performed under emergency conditions. The patient had virilization and hoarsening of the voice before surgery. Intraoperatively, a 21-cm ovarian mass was detected and resected with unilateral salpingo-oophorectomy. Conclusion: A histopathological examination of the tumor showed a tumor with cystic degeneration, necrosis, hemorrhage, and tumoral embolism. The pathological examination revealed ovarian SCT. Virilization was resolved immediately after the surgery. In women with virilization who give birth to a fetus with ambiguous genitalia, SCTs should be kept in mind