Juvenile granulosa cell tumor: 20 years’ experience of a Tertiary Center

Objectives: The aim of this study is to share of the 20-year experience of a tertiary center about juvenile granulosa cell tumor (JGCT) and describe clinic manifestations, treatment, and outcome of patients who diagnosed JGCT.Material and methods: Five patients who diagnosed juvenile granulosa cell tumor between 2000 and 2020 were included in the study. The demographics, clinical findings and outcomes were retrospectively evaluated. Of the 5 patientsin our study, one was in the premenarcheal girl. The common complaint in all of our patients was abdominal swelling. In preoperative imaging methods, all patients had unilateral adnexal mass and no signs in favor of metastasis. All patients were staged according to FIGO classification for ovarian tumors; 3 of patients had stage IA disease, one of patients had stage IC1 and one of patients had stage IC2. All patients underwent different surgecal procedures which is appropriate for their clinical manifestations. In addition to surgery 2 patients received adjuvant chemotherapy.Results: The median follow-up period of the patients was 60 mounts and recurrence was observed in two patients whowere reoperated. We have no patients who died due to this disease.Conclusions: Possible diagnosis of juvenile granulosa cell tumor should be kept in mind in a patient of young age with unilateral adnexal mass with benign features

A viable childbirth after correction of spontaneous uterine dehiscence

We report a case of uterine dehiscence during pregnancy. Uterine dehiscence and rupture are serious complications of pregnancy. This situation takes place especially in women that prior uterine operation(s). We represent a 30-year-old woman diagnosed uterine dehiscence at 22nd gestation week. Uterine dehiscence treated surgically and then medical treatment was given to prevent preterm labour. At 34th gestation week, the patient was operated because of preterm labour and an alive foetus was born. The result of the pathologic examination of the placenta: Placental adhesion failure was detected. In conclusion women with prior caesarean delivery (one or more), ultrasound measurement should be recommended for measuring the lower uterine segment thickness in order to predict the possibility of uterine dehiscence and rupture

Prognostic Factors and Tumor Infiltrating Lymphocytes in Triple Negative Breast Cancer

Objective: Triple-negative-breast-cancer (TNBC) is a very heterogenous disease some of which are very aggressive and have poor prognosis. No targeted therapy is available. Immune response and tumor-infiltrating lymphocytes (TIL) can be related to longer disease-free survival (DFS) and overall survival (OS) in TNBC. Family history of cancer can be related poor prognosis, irrespective of genetic mutation

Comparison of Core Biopsy and Excision Materials in Terms of Histological Type, Histological Grade, Hormone Receptors, and Human Epidermal Growth Factor Receptor 2 Expression in Invasive Breast Carcinomas

Y OBJECTIV

Adjuvant Treatment Modalities, Prognostic Factors, and Outcome of the Uterine Carcinosarcoma

Objective: To determine the impact of adjuvant therapy and other factors associated with the recurrence and survival of patients with uterine carcinosarcoma (UCS)