Reactions of 1-amino-5-benzoyl-4-phenyl-1H-pyrimidine-2-thione with carbonyl reactives

The 1-amino-5-benzoyl-4-phenyl-1H-pyrimidine-2-thione (1) was obtained by starting from 4-benzoyl-5-phenyl-2,3-furandione and acetophenonthiosemicarbazone. In this study, the investigations were extended to reactions of the compound 1 with ethylacetoacetate, benzalacetophenone, cyanoacetic acid, benzyl and acetylchloride (2a-e). Thus, some new pyrimidine derivatives (3a-e) were synthesized. The structures of these compounds were determined by elemental analysis, IR, H-1 NMR spectroscopic measurements.</p

“Synthesis of Spectral Studies of Some 2-Oxopyrimidine-1(2H)-yl]-pyrrolidine-2,5-dione Derivatives”

1-Amino-5-(4-methylbenzoyl)-4-(4-methylphenyl)pyrimidine-2(1H)-one/-thione (1a,b) reacted with various carboxylic anhydrides (2a-d) under different conditions and given the new amide and imide derivatives (3a-h). The newly synthesized compounds were characterized by elemental analysis, IR, 1H and 13C NMR spectral data. All compounds were compared with their previous analogues

Reactions of 1-amino-5-benzoyl-4-phenyl-1H-pyrimidine-2-one/thione compounds with unsymmetrically 1,3-substituted diketones

1-Amino-5-benzoyl-4-phenyI-1H-pyrimidine-2-one/thione (1) react with several unsymmetrically 1,3-substituted diketones (2a-f) under different conditions to give the new imine derivatives (3a-f). Unsymmetrically 1,3-substituted diketones derivatives (2a-f) were obtained from 1,5-di-(4-aryl)-4,5-dibromo-1-pentene-3-one and sodium methoxide. All newly synthesized compounds were characterized by elemental analysis, IR and H-1 NMR spectral data

Ulein’in Total Sentezine Giriş

In this part of the study of total synthesis ulein, 3-ethyl-1,2,3,4-tetrahydrocarbazole (1) has been obtained from phenylhydrazinium hycrochloride with 4-ethylcyclohexanon in the atmosphere of nitrogen. 3-Ethyl-1-oxo-1,2,3,4-tetrahydrocarbazole (2) has been synthesized from the reaction of oxidation of 3-ethyl-1,2,3,4-tetrahydrocarbazole (1). The structures of these compounds were determined by IR-, 1H-NMR spectroscopic data and elemental analysis

Reactions of N-Aminopyrimidine derivatives with 1,3-dicarbonyl compounds

The reactions of 1-Amino-pyrimidine derivatives (1) and some 1,3-dicarbonyl compounds (2) were realized in the presence of p-toluensulfonic acid catalyst to give convenient enamine (3) and/or imine derivatives (4). In the same way, the enamine (5) and/or imine derivatives (6) were synthesized using (1) and 1,3-indanedione which is one of the different 1,3-dicarbonyl compounds. The molecular structures of all the prepared compounds were determined by H-1-nmr, C-13-nmr, i.r. spectra and elemental analyses, and were drawn by taking imine-enamine tautomerism into account

Reactions of 1-amino-5-benzoyl-4-phenyl-1H-pyrimidine-2-thione with various carboxylic anhydrides

l-Amino-5-benzoyl-4-phenyl-lH-pyrimidine-2-thione (1) reacts with various carboxylic anhydrides (2a-e) under different conditions and gives the new amide and imide derivatives. Reaction of (1) with maleic anhydride (2b) resulted in acid derivative (3b). The structures of these compounds (3a-f) were determined by H-1 NMR, C-13 NMR, IR spectra and elemental analysis

1-Amino-5-benzoil-4-fenil-1H-pirimidin-2-on Bileşiğinin Bazı Karbonil Reaktifleriyle Reaksiyonlarının İncelenmesi

The 1-amino-5-benzoyl-4-phenyl-1H-pyrimidine-2-thione 1 was obtained by starting from 4-benzoyl-5-phenyl-2,3-furandione and acetophenonthiosemicarbazone. In this study, the investigations were extended to reactions of 1 with ethylacetoacetate, benzalacetophenon, cyanoaceticacid, benzyl, benzoin and acetylchloride. Thus, some new pyrimidine derivatives (1a-e) were synthesized. The structures of these compounds were determined by the IR-, 1H-NMR spectroscopic data and elemental analysis