Additional file 3: of DNA methylation patterns associated with oxidative stress in an ageing population

Supplemental Tables. Table S1. Methylation sites associated with TGSH (FDR <0.05). Table S2. Methylation sites associated with GSH (FDR <0.05. Table S3. Methylation sites associated with GSSG (FDR <0.05). Table S4. Methylation sites associated with ratio of GSSG-to-GSH (FDR <0.05). Table S5. Methylation sites associated with levels of HCY (FDR <0.05). Table S6. Methylation sites associated with levels of oxLDL (FDR <0.05). Table S7. Methylation sites associated with levels of CD (FDR <0.05). Table S8: Methylation sites associated with BCD-LDL (FDR <0.05). (XLS 185 kb

Additional file 1: of DNA methylation patterns associated with oxidative stress in an ageing population

Supplementary Data. Figure S1. Plot showing the first two PC components of the PIVUS genotype data with the 1000G multi population reference panel. Figure S3. Comparison of regression coefficients from the primary and secondary models (additionally adjusted for BMI) for oxidative marker BCD-LDL. Table S9. Enrichment in JASPAR transcription factor binding site motifs in genes annotated to oxidative stress associated CpGs (Bonferroni-adjusted p-value < 0.05). Table S10. Enriched biological process among genes annotated to oxidative marker associated CpGs (adjusted p-value < 0.05). Table S11. Enriched annotation clusters among genes annotated to oxidative marker CpGs (enrichment score > 1). Table S12. Significant lead cis-meQTL SNPs of oxidative marker CpGs (FDR <0.05). Table S13. Overlap across genotype-CpG (FDR <0.05), genotype-phenotype (p-value <0.001), and CpG-phenotype (FDR <0.05) results. (DOCX 135 kb