Evaluasi Penggunaan Antibiotik Pada Pasien Penyakit Paru Obstruktif Kronik Eksaserbasi Akut Di Instalasi Rawat Inap RSUD Dr. Moewardi Tahun 2016-2017

Chronic Obstructive Pulmonary Disease (COPD) is a disease with limited air flow that is not completely reversible while exacerbation is a condition of a disease worsening. By 2020 the WHO estimates COPD to be the top three most common cause of death. One treatment of acute exacerbation of COPD is using of antibiotics. The inappropriate use of antibiotics can lead to treatment failure and resistance. The purpose of this study was to evaluate the use of antibiotics in patients with acute exacerbation of COPD at Dr. Moewardi Hospital in 2016-2017 based on parameters proper indication, proper patient, proper drug and proper dosage. This study was a non-experimental descriptive research category, retrospectively retrieved data by viewing medical records of patients with acute exacerbation of COPD. Sampling using purposive sampling method and obtained as many as 30 samples. The inclusion criteria of this study were patients with acute exacerbation of COPD who received antibiotics from 2016-2017 with complete medical record data. The exclusion criteria of this study were the patient died and there were other infections. The most commonly used antibiotics were ceftriaxone (33.3%), levofloxacin (16.7%), ciprofloxacin (6.7%), and co-amoxiclav (6.7%). Results of the evaluation of antibiotic drug use in 30 patients with acute exacerbations of COPD at Dr. Moewardi Hospital 2016-2017 was 83.3% proper indication, 80,0 % proper patient, 53,3 % proper drug, and 33,3 % proper dosage

Evaluasi Penggunaan Antibiotik Pada Balita Dengan Diare Akut Di Instalasi Rawat Inap Rsud Dr. Moewardi Periode September-Desember 2015

Diarrhea is one of the most disease with high morbidity and mortality of children under five years in the Worldwide with 3 million death annually. The cause of acute diarrhea is various, it can be caused by viruses, bacterias and pathogens. Antibiotics can used to treatment acute diarrhea but not all of diarrhea should be given with antibiotics. Antibiotics are only useful for patient with blood diarrhea (dysentery), cholera and other infectious diseases. The purpose of this study were to describe and evaluate the use of antibiotics in infant patients with acute diarrhea in Dr.Moewardi Hospital period September until December 2015. This study was a non-experimental study (observational),the data were obtained rFetrospectively from patient’s medical records. Evaluation of the use of antibiotics was seen from right indication, right drug, right patient, right dose and frequency then the right of duration based on Pelayanan Kesehatan Anak di Rumah Sakit 2009 and empirical treatment of acute infectious diarrhea 2006 standart treatment. The results of this research on acute diarrhea with diagnosis dysentery and acute diarrhea at Dr. Moewardi hospital antibiotic that being used is ampicillin (31,43%), amoxicillin (20%), metronidazole (17,14%), cefotaxime (11,43%), Kotrimoksazol (5,71%) and Cefixime (2,86%). The results of evaluation antibiotics is right indication (85,71%), right patient (87,71%), right drug (52,28%), the right dose and frequency (34,28%), right duration (34,28%), and rationality (34,28% )

Evaluasi Penggunaan Obat Analgetik Pada Pasien Osteoartritis di Instalasi Rawat Jalan RSUD Dr. Moewardi Surakarta Tahun 2015

Osteoarthritis (OA) is a chronic rheumatic disease that is a major cause loss of physic function and disability. Osteoarthritis may affect several joints in the neck, hips, knees, five bones in the fingers and toes. Prevalention osteoarthritis in Indonesia reached 36.5 million people in 2007 where the majority patients are elderly. Osteoarthritis patients feel pain that will affect on reduced quality of life’s patients. The purpose of this study are to describe and evaluate analgesic prescription in patients with osteoarthritis at Dr. Moewardi Surakarta Hospital in 2015 based on parameters proper indication, proper patient, proper drug and proper dosage. This study was a non experimental research. Data was obtained retrospectively from medical records of patients with osteoarthritis. Data was descriptively analyzed one hundred patients were included as sample by purposive sampling method. Inclusion criteria of this study was patient’s with osteoarthritis who accept analgesics prescription in 2015 with complete medical record. Exclusion criteria of this study was pregnant patients. An overview of analgesic use in osteoarthritis patients starting from the highest are paracetamol (42%), sodium diclofenac (38%), meloxicam (10%), metampiron (3%), mefenamic acid (4%), ibuprofen (2%) and celecoxib (1%). The result of this study is 100% proper indications, 71% proper patient, 71% proper drug and the 55% proper dosage

Hubungan Tingkat Pengetahuan dengan Ketepatan Penggunaan Obat Analgetik pada Swamedikasi Nyeri Gigi di Masyarakat Kabupaten Sukoharjo

Dental pain is a disease that usually affects the pulp or tissue around the teeth. Dental pain includes mild pain that is easily recognizable for signs and symptoms, it encourages a person to do his own treatment without the help of a health professional or often called self care. Self care should be in accordance with the patient's condition and saturate the parameters of right indication, right drug, right dose, and right patient. This study aims to determine the relationship of knowledge level with the accuracy of the use of drugs to self care dental pain conducted by the community. Sampling in this study cluster sampling counted 154 respondents. Non experimental research conducted on Sukoharjo district community with comparatif method. Retrieval of data byretrospectively. Data were analyzed using cross sectional design and tested using SPSS test by chi square test. The results obtained in this study is the result of the level of knowledge of the average society belonging to the category enough value 57.79%, the accuracy of the use of analgesic drugs as much as 39 respondents accurate and inappropriate respondents use analgesic drugs as much as 115 respondents, The use of analgesic drugs on self care tooth pain shows a correlation between the level of knowledge and the use of analgesic drugs on self care tooth pain characterized by p value 0,000. Keyword : Tooth pain, analgesic use drug, knowledge, self car

Analisis Drug Related Problems Terkait Dengan Ketidaktepatan Dosis Dan Interaksi Obat Pada Pasien Penyakit Paru Obstruksi Kronik (PPOK) Di RSUD DR. Moewardi Tahun 2015

Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disorder that the incidence is increasing year by year. It is important to monitor the treatment of COPD in order to achieve optimal therapy. This study aims to determine the description and analyze the incidence of DRPs associated with the inaccuracy of dosage and drug interactions in patients with COPD in Dr. Moewardi Hospital in 2015. This research was non experimental research with retrospective retrieval data which was analyzed descriptively. Samples were collected with purposive sampling method. The inclusion criteria for this study were patients diagnosed with COPD, getting 2 or more of the drugs used together, and having complete medical record data. Data analysis of dosage inaccuracy was evaluated using British National Formulary Edition 61 2011, Drug Information Handbook 17th, Informatorium Obat Nasional Indonesia 2008. Analysis of potential drug interactions was evaluated using Stockley's Drug Interaction in 2008 and drug interaction checker www.drugs.com/druginteractions.html. Based on the results of the study, 40 medical records of patients with DRP incidence were 30 (75%) and those without DRPs were 10 patients (25%). The dosage incompatibility category had 9 patients (10%) consisting of 2 patients (5%) getting high dose and 8 patients (20%) getting low dose. While for drug interaction event category there were 30 patients (75%) 0f 85 cases, covering major severity were 21 cases (24,7%), moderate counted 56 cases (65,9%), and minor were 8 cases (19,4% )

Faktor-Faktor Yang Berpengaruh Terhadap Kepatuhan Minum Obat Pasien Diabetes Mellitus Tipe 2 Di RSUD Dr. Moewardi Periode Oktober 2016–Maret 2017

Type 2 diabetes mellitus is a metabolic disease marked by increased levels of glucose caused by resistance to the hormone insulin. Diabetes mellitus is a disease cronys chronically so that compliance with medication is crucial in the therapeutic treatment of diabetes mellitus and lowers the risk of complications. This research aims to know the factors that influence on patient medication adherence to diabetes mellitus type 2 in the RSUD Dr. Moewardi. The methods used for this research a cross sectional with purposive samplingtechnique. The number of samples in the study of 98 outpatient diabetes mellitus type 2 in the RSUD. Dr. Moewardi that do control in October 2016 to March 2017. The instruments used in this study was a questionnaire. Data analysis in bivariat and multivariate. Bivariat analysis usedchi square test and calculation of value OR (Odd Ratio). While multivariate analysis using logistic regression. The results showed that the factors that influence on patient medication adherence to diabetes mellitus type 2 in the RSUD Dr. Moewardi are the frequency of drug (p-value = 0,04 dan OR = 4,656) and sex(p-value = 0,063 dan OR = 2,803). Factors which do not affect drug compliance of type 2 diabetes mellitus patients in the RSUD Dr. Moewardi are the number of medications(p-value = 0,049 dan OR = 2,448), age(p-value = 1,000 dan OR = 1,169), duration of use of the drug(p-value = 0,375 dan OR = 1,572), and complications(p-value = 0,476 dan OR = 0,669)

Systematic Review: Adverse Drug Reaction Dan Outcome Terapi Antituberculosis Pada Pasien Tb-Mdr

ABSTRACT Systematic Review: Adverse Drug Reaction and Outcome of Antituberculosis Therapy in MDR-TB Patients; TB-MDR is a condition where resistance occurs against two first-line drugs, rifampicin and isoniazid, with or without resistance to other antituberculosis drugs. Adverse Drug Reactions (ADRs) are the body's response to harmful or unwanted drugs occurring at the usual doses used in humans. ADRs often emerge during the treatment of MDR-TB patients. The aim of this study is to provide an overview of adverse drug reactions and the outcomes of antituberculosis therapy in MDR-TB patients. This Study adopts a systematic review design of cohort and cross-sectional studies. Articles used in this study were obtained from various databases, including PubMed and Google Scholar. and were published between 2011 and 2022. Article collection followed the PRISMA flow diagram. A total of 16 articles were identified, with 3 articles from Europe, 9 articles from Asia, and 4 articles from Africa. The results of ADR occurrence search showed that 1430 patients experienced at least one ADR finding, with a total of 3012 ADR findings. The conclusion drawn from this study is that ADRs resulting from MDR-TB therapy are experienced by patients, with the most common ADR occurrence being gastrointestinal disorders (nausea, vomiting, dyspepsia, acute abdomen) in 845 patients (35.82%). The desired outcome was achieved in 55.44% or 1730 patients, with a breakdown of 47.95% (1441 patients) having recovered and 9.62% (289 patients) having completed the treatment. Meanwhile, the undesired outcome constituted 42.49% or 1280 patients

Evaluasi Penggunaan Antibiotik pada Penderita Diabetes Melitus Tipe 2 dengan Komplikasi Ulkus/Gangren di Instalasi Rawat Inap RSUD Dr. Moewardi Surakarta Tahun 2015

Diabetes mellitus is a disease that requires long-term treatment that would otherwise be handled properly can cause complications of ulcer/gangrene. Diabetic ulcers are open sores that contained surface of the skin or mucous membranes that can be invaded by the bacteria causing the infection and need treatment with antibiotics. The need for accuracy in the selection of antibiotics intended to allow the ulcer healed quickly so it does not harm the patient. This study aims to determine the accuracy of the use of antibiotics in patients with type 2 diabetes mellitus with complications of ulcer/gangrene in RSUD Dr. Moewardi. This study is a non-experimental descriptive by observation of the patient record ulcers diabetic who underwent inpatient and get a prescription of antibiotics by comparing the list of drugs in the medical records of patients with the literature based on criteria appropriate indication, right patient, right drug and the right dosage. The study was conducted at RSUD Dr. Moewardi Surakarta. The results of the study in 21 patients with type 2 diabetes mellitus with complications of ulcer/gangrene shows the antibiotics used in RSUD Dr. Moewardi is metronidazole (4.8%), vancomycin (4.8%) and antibioticsmetronidazole combination is ceftriaxone (47 , 6%), ceftriaxone-metronidazoleclindamycin (4.8%), levofloxacin-azithromycin-ceftriaxone (4.8%), cotrimoxazole-ciprofloxacin (4.8%), metronidazole-meropenem (4.8%), ceftriaxone -metronidazol-gentamicin (4.8%), metronidazole-clindamycinciprofloxacin (4.8%), ceftriaxone-levofloxacin (4.8%), and ceftriaxonemetronidazole- ciprofloxacin (9.5%). The results of the evaluation according to criteria appropriate usage of antibiotics that is 100% accurate indication, a 100% appropriate of patient, 42.3% for drug, and 61.9% for dose