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    Extending the Nested Parallel Model to the Nested Dataflow Model with Provably Efficient Schedulers

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    The nested parallel (a.k.a. fork-join) model is widely used for writing parallel programs. However, the two composition constructs, i.e. "βˆ₯\parallel" (parallel) and ";;" (serial), are insufficient in expressing "partial dependencies" or "partial parallelism" in a program. We propose a new dataflow composition construct "⇝\leadsto" to express partial dependencies in algorithms in a processor- and cache-oblivious way, thus extending the Nested Parallel (NP) model to the \emph{Nested Dataflow} (ND) model. We redesign several divide-and-conquer algorithms ranging from dense linear algebra to dynamic-programming in the ND model and prove that they all have optimal span while retaining optimal cache complexity. We propose the design of runtime schedulers that map ND programs to multicore processors with multiple levels of possibly shared caches (i.e, Parallel Memory Hierarchies) and provide theoretical guarantees on their ability to preserve locality and load balance. For this, we adapt space-bounded (SB) schedulers for the ND model. We show that our algorithms have increased "parallelizability" in the ND model, and that SB schedulers can use the extra parallelizability to achieve asymptotically optimal bounds on cache misses and running time on a greater number of processors than in the NP model. The running time for the algorithms in this paper is O(βˆ‘i=0hβˆ’1Qβˆ—(t;Οƒβ‹…Mi)β‹…Cip)O\left(\frac{\sum_{i=0}^{h-1} Q^{*}({\mathsf t};\sigma\cdot M_i)\cdot C_i}{p}\right), where Qβˆ—Q^{*} is the cache complexity of task t{\mathsf t}, CiC_i is the cost of cache miss at level-ii cache which is of size MiM_i, Οƒβˆˆ(0,1)\sigma\in(0,1) is a constant, and pp is the number of processors in an hh-level cache hierarchy

    Dynamic surface: An Extrapolation of biodesign

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    Doctor of Philosophy

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    dissertationMagnetic Resonance (MR) is a relatively risk-free and flexible imaging modality that is widely used for studying the brain. Biophysical and chemical properties of brain tissue are captured by intensity measurements in T1W (T1-Weighted) and T2W (T2-Weighted) MR scans. Rapid maturational processes taking place in the infant brain manifest as changes in co{\tiny }ntrast between white matter and gray matter tissue classes in these scans. However, studies based on MR image appearance face severe limitations due to the uncalibrated nature of MR intensity and its variability with respect to changing conditions of scan. In this work, we develop a method for studying the intensity variations between brain white matter and gray matter that are observed during infant brain development. This method is referred to by the acronym WIVID (White-gray Intensity Variation in Infant Development). WIVID is computed by measuring the Hellinger Distance of separation between intensity distributions of WM (White Matter) and GM (Gray Matter) tissue classes. The WIVID measure is shown to be relatively stable to interscan variations compared with raw signal intensity and does not require intensity normalization. In addition to quantification of tissue appearance changes using the WIVID measure, we test and implement a statistical framework for modeling temporal changes in this measure. WIVID contrast values are extracted from MR scans belonging to large-scale, longitudinal, infant brain imaging studies and modeled using the NLME (Nonlinear Mixed Effects) method. This framework generates a normative model of WIVID contrast changes with time, which captures brain appearance changes during neurodevelopment. Parameters from the estimated trajectories of WIVID contrast change are analyzed across brain lobes and image modalities. Parameters associated with the normative model of WIVID contrast change reflect established patterns of region-specific and modality-specific maturational sequences. We also detect differences in WIVID contrast change trajectories between distinct population groups. These groups are categorized based on sex and risk/diagnosis for ASD (Autism Spectrum Disorder). As a result of this work, the usage of the proposed WIVID contrast measure as a novel neuroimaging biomarker for characterizing tissue appearance is validated, and the clinical potential of the developed framework is demonstrated

    Mass-produced handmade ceramics

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