ADD3 (adducin 3)

Review on ADD3 (adducin 3), with data on DNA, on the protein encoded, and where the gene is implicated

t(10;11)(q25;p15)

Review on t(10;11)(q25;p15), with data on clinics, and the genes involved

PDGFRB (platelet-derived growth factor receptor, beta polypeptide)

Review on PDGFRB (platelet-derived growth factor receptor, beta polypeptide), with data on DNA, on the protein encoded, and where the gene is implicated

Congreso Eucarístico Nacional

Del 17 al 23 de junio se celebró en Sevilla el séptimo Congreso Eucarístico Nacional de España y el primero después del Concilio Vaticano II. La siguiente nota señala los principales momentos y contenidos de dicha celebración

t(6;8)(q27;p12)

Review on t(6;8)(q27;p12), with data on clinics, and the genes involved

TICdb: a collection of gene-mapped translocation breakpoints in cancer

BACKGROUND: Despite the importance of chromosomal translocations in the initiation and/or progression of cancer, a comprehensive catalog of translocation breakpoints in which these are precisely located on the reference sequence of the human genome is not available at present. DESCRIPTION: We have created a database that describes the genomic location of 1,225 translocation breakpoints in human tumors, corresponding to 247 different genes, using information from publicly available sources. Junction sequences from reciprocal translocations were obtained from 655 different references (either from the literature or from nucleotide databases), and were mapped onto the reference sequence of the human genome using BLAST. All translocation breakpoints were thus referred to precise nucleotide positions (949 breakpoints) or gene fragments (introns or exons, 276 breakpoints) within specific Ensembl transcripts. CONCLUSION: TICdb is a comprehensive collection of finely mapped translocation breakpoints, freely available at . It should facilitate the analysis of sequences encompassing translocation breakpoints and the identification of factors driving translocation events in human tumors

Brave New World, una visión arquitectónica

El trabajo consiste en un análisis de la arquitectura y el urbanismo en "Un mundo feliz" (Brave New World) y de la investigación de las principales ideas sobre los mismos de su autor, Aldous Huxley.  Uno de los objetivos principales es pensar y proponer localizaciones existentes que pudieran transmitir las sensaciones y la reflexión que transmite la novela, aportando mediante la arquitectura actual una dosis de realismo y cercanía a ese Brave New World que anticipaba Huxley en su obra. Por lo tanto, se finaliza  el trabajo con un pequeño documento audiovisual en forma de corto como síntesis y refuerzo de lo aportado en el trabajo teórico