Relying on storage or ICT? How to maintain low voltage grids' stability with an increasing feed-in of fluctuating renewable energy sources

Since the beginning of the new century our electricity system is changing rapidly. Distributed energy resources, such as wind or solar energies are becoming more and more important. These energies are producing fluctuating electricity, which is fed into low voltage distribution grids. The resulting volatility complicates the exact balancing of demand and supply. These changes can lead to distribution grid instabilities, damages of electronic devices or even power outages and might therefore end in deadweight losses affecting all electricity users. A concept to tackle this challenge is matching demand with supply in real-time, which is known as smart grids. In this study, we focus on two smart grids' key components: decentralized electricity storages and smart meters. The aim of this study is to provide new insights concerning the low diffusion of smart meters and decentralized electricity storages and to examine whether we are facing situations of positive externalities. During our study we conducted eight in-depth expert interviews. Our findings show that the diffusion of smart meters as well as decentralized electricity storages is widely seen as beneficial to society. This study identifies the most important stakeholders and various related private costs and benefits. As private benefits are numerous but widely distributed among distinct players, we argue that we face situations of positive externalities and thus societal desirable actions are omitted. We identify and discuss measures to foster diffusion of the two studied smart grid key components. Surprisingly, we find that direct interventions like subsidies are mostly not seen as appropriate even by experts from industries that would directly benefit from them. As the most important point, we identified well-designed and clearly defined regulatory and legal frameworks that are free of contradictions. --smart meter,decentralized electricity storage,smart grid,externality

The Effects of Teaching Text Structures Through Social Studies Content on Second Graders\u27 Expository Reading Comprehension

The purpose of the study was to determine the effect of explicitly teaching expository text structure on second graders\u27 social studies reading comprehension. Participants were 18 second graders from a small Midwestern town. All students were part of the same treatment group. The researcher instructed students on how to identify and comprehend compare/contrast and cause/effect expository text structure. The instruction for the text structures occurred for three weeks each for a total of a six week study. The researcher instructed students with modeling, guided practice and independent practice through the use of graphic organizers. Findings suggested very little effect of treatment. Several strengths and limitations of the study are discussed, as well as implications for future research

IST Austria Thesis

The aim of this thesis was the development of new strategies for optical and optogenetic control of proliferative and pro-survival signaling, and characterizing them from the molecular mechanism up to cellular effects. These new light-based methods have unique features, such as red light as an activator, or the avoidance of gene delivery, which enable to overcome current limitations, such as light delivery to target tissues and feasibility as therapeutic approach. A special focus was placed on implementing these new light-based approaches in pancreatic β-cells, as β-cells are the key players in diabetes and especially their loss in number negatively affects disease progression. Currently no treatment options are available to compensate the lack of functional β-cells in diabetic patients. In a first approach, red-light-activated growth factor receptors, in particular receptor tyrosine kinases were engineered and characterized. Receptor activation with light allows spatio-temporal control compared to ligand-based activation, and especially red light exhibits deeper tissue penetration than other wavelengths of the visible spectrum. Red-light-activated receptor tyrosine kinases robustly activated major growth factor related signaling pathways with a high temporal resolution. Moreover, the remote activation of the proliferative MAPK/Erk pathway by red-light-activated receptor tyrosine kinases in a pancreatic β-cell line was also achieved, through one centimeter thick mouse tissue. Although red-light-activated receptor tyrosine kinases are particularly attractive for applications in animal models due to the deep tissue penetration of red light, a drawback, especially with regard to translation into humans, is the requirement of gene therapy. In a second approach an endogenous light-sensitive mechanism was identified and its potential to promote proliferative and pro-survival signals was explored, towards light-based tissue regeneration without the need for gene transfer. Blue-green light illumination was found to be sufficient for the activation of proliferation and survival promoting signaling pathways in primary pancreatic murine and human islets. Blue-green light also led to an increase in proliferation of primary islet cells, an effect which was shown to be mostly β-cell specific in human islets. Moreover, it was demonstrated that this approach of pancreatic β-cell expansion did not have any negative effect on the β-cell function, in particular on their insulin secretion capacity. In contrast, a trend for enhanced insulin secretion under high glucose conditions after illumination was detected. In order to unravel the detailed characteristics of this endogenous light-sensitive mechanism, the precise light requirements were determined. In addition, the expression of light sensing proteins, OPN3 and rhodopsin, was detected. The observed effects were found to be independent of handling effects such as temperature differences and cytochrome c oxidase dependent ATP increase, but they were found to be enhanced through the knockout of OPN3. The exact mechanism of how islets cells sense light and the identity of the photoreceptor remains unknown. Summarized two new light-based systems with unique features were established that enable the activation of proliferative and pro-survival signaling pathways. While red-light-activated receptor tyrosine kinases open a new avenue for optogenetics research, by allowing non-invasive control of signaling in vivo, the identified endogenous light-sensitive mechanism has the potential to be the basis of a gene therapy-free therapeutical approach for light-based β-cell expansion

Staphylinidae and Carabidae overwintering in wheat and sown wildflower areas of different age

Species richness and abundance of staphylinid and carabid beetles overwintering in winter wheat fields and 1- to 3-year-old wildflower areas were investigated during 2000/2001 on 16 study sites in Switzerland. Abundance and species richness of overwintering staphylinids significantly increased with successional age of the wildflower areas and were always higher in older wildflower areas than in winter wheat. A similar but less distinct pattern was observed for the abundance and species richness of carabid beetles. The influence of habitat parameters (vegetation cover, fine sand content, organic matter, pH, soil pore volume, surrounding landscape structure, habitat area) on the staphylinid and carabid assemblages based on the number of individuals per species and site was analysed using canonical correspondence analysis. Vegetation cover was the most significant parameter significantly characterizing both staphylinid and carabid assemblages. The amount of vegetation cover explained 15.7% of the variance, fine sand content accounted for 13.3% and surrounding landscape structure for 10.9% of the variance in the staphylinid assemblage. In the carabid assemblage, vegetation cover was the only significant factor, explaining 24.7% of the variance. This study showed for the first time that the significance of wildflower areas as a reservoir for hibernation for generalist predatory beetles increases with progressing successional ag

Cytochromes P450: a success story

Cytochrome P450 proteins, named for the absorption band at 450 nm of their carbon-monoxide-bound form, are one of the largest superfamilies of enzyme proteins. The P450 genes (also called CYP) are found in the genomes of virtually all organisms, but their number has exploded in plants. Their amino-acid sequences are extremely diverse, with levels of identity as low as 16% in some cases, but their structural fold has remained the same throughout evolution. P450s are heme-thiolate proteins; their most conserved structural features are related to heme binding and common catalytic properties, the major feature being a completely conserved cysteine serving as fifth (axial) ligand to the heme iron. Canonical P450s use electrons from NAD(P)H to catalyze activation of molecular oxygen, leading to regiospecific and stereospecific oxidative attack of a plethora of substrates. The reactions carried out by P450s, though often hydroxylation, can be extremely diverse and sometimes surprising. They contribute to vital processes such as carbon source assimilation, biosynthesis of hormones and of structural components of living organisms, and also carcinogenesis and degradation of xenobiotics. In plants, chemical defense seems to be a major reason for P450 diversification. In prokaryotes, P450s are soluble proteins. In eukaryotes, they are usually bound to the endoplasmic reticulum or inner mitochondrial membranes. The electron carrier proteins used for conveying reducing equivalents from NAD(P)H differ with subcellular localization. P450 enzymes catalyze many reactions that are important in drug metabolism or that have practical applications in industry; their economic impact is therefore considerable

Conservation and diversity of gene families explored using the CODEHOP strategy in higher plants

BACKGROUND: Availability of genomewide information on an increasing but still limited number of plants offers the possibility of identifying orthologues, or related genes, in species with major economical impact and complex genomes. In this paper we exploit the recently described CODEHOP primer design and PCR strategy for targeted isolation of homologues in large gene families. RESULTS: The method was tested with two different objectives. The first was to analyze the evolution of the CYP98 family of cytochrome P450 genes involved in 3-hydroxylation of phenolic compounds and lignification in a broad range of plant species. The second was to isolate an orthologue of the sorghum glucosyl transferase UGT85B1 and to determine the complexity of the UGT85 family in wheat. P450s of the CYP98 family or closely related sequences were found in all vascular plants. No related sequence was found in moss. Neither extensive duplication of the CYP98 genes nor an orthologue of UGT85B1 were found in wheat. The UGT85A subfamily was however found to be highly variable in wheat. CONCLUSIONS: Our data are in agreement with the implication of CYP98s in lignification and the evolution of 3-hydroxylation of lignin precursors with vascular plants. High conservation of the CYP98 family strongly argues in favour of an essential function in plant development. Conversely, high duplication and diversification of the UGT85A gene family in wheat suggests its involvement in adaptative response and provides a valuable pool of genes for biotechnological applications. This work demonstrates the high potential of the CODEHOP strategy for the exploration of large gene families in plants

Cg-Rel, the first Rel/NF-κB homolog characterized in a mollusk, the Pacific oyster Crassostrea gigas

AbstractWe report here the identification and functional characterization of Cg-Rel, a gene encoding the Crassostrea gigas homolog of Rel/NF-κB transcription factors found in insects and mammals. Sequence and phylogenetic analysis showed that Cg-Rel shares the structural organization of Rel/NF-κB transcription factors of class II. It includes a Rel homology domain as well as a C-terminal transactivation domain (TD). Overexpression of Cg-Rel in the Drosophila S2 cell line activated the expression of a NF-κB-dependent reporter gene, whereas transfection with a Cg-Rel construct containing a C-terminal deletion of the TD or using a reporter gene with mutated κB binding sites failed to activate expression. These results suggest that Cg-Rel is a functional member of the Rel family of transcription factors, making this the sixth structurally homologous component of the Rel/NF-κB pathway characterized in C. gigas. Based on homology to other invertebrates’ Rel/NF-κB cascade, the function of the oyster pathway may serve to regulate genes involved in innate defense and/or development. These findings serve to highlight a potentially important regulatory pathway to the study of oyster immunology, hence allowing comparison of the immune system in vertebrates and invertebrates, an important key issue to understand its evolution

ZEPLIN-III direct dark matter search : final results and measurements in support of next generation instruments

Astrophysical observations give convincing evidence for a vast non-baryonic component, the so-called dark matter, accounting for over 20% of the overall content of our Universe. Direct dark matter search experiments explore the possibility of interactions of these dark matter particles with ordinary baryonic matter via elastic scattering resulting in single nuclear recoils. The ZEPLIN-III detector operated on the basis of a dualphase (liquid/gas) xenon target, recording events in two separate response channels { scintillation and ionisation. These allow discrimination between electron recoils (from background radiation) and the signal expected from Weakly Interacting Massive Particle (WIMP) elastic scatters. Following a productive first exposure, the detector was upgraded with a new array of ultra-low background photomultiplier tubes, reducing the electron recoil background by over an order of magnitude. A second major upgrade to the detector was the incorporation of a tonne-scale active veto detector system, surrounding the WIMP target. Calibration and science data taken in coincidence with ZEPLIN-III showed rejection of up to 30% of the dominant electron recoil background and over 60% of neutron induced nuclear recoils. Data taking for the second science run finished in May 2011 with a total accrued raw fiducial exposure of 1,344 kg days. With this extensive data set, from over 300 days of run time, a limit on the spin-independent WIMP-nucleon cross-section of 4.8 10-8 pb near 50 GeV/c2 WIMP mass with 90% confidence was set. This result combined with the first science run of ZEPLIN-III excludes the scalar cross-section above 3.9 10-8 pb. Studying the background data taken by the veto detector allowed a calculation of the neutron yield induced by high energy cosmic-ray muons in lead of (5.8 0.2) 10-3 neutrons/muon/(g/cm2) for a mean muon energy of 260 GeV. Measurements of this kind are of great importance for large scale direct dark matter search experiments and future rare event searches in general. Finally, this work includes a comprehensive measurement of the energy dependent quenching factor for low energy nuclear recoils in a plastic scintillator, such as from the ZEPLIN-III veto detector, increasing accuracy for future simulation packages featuring large scale plastic scintillator detector systems

Les interactions sociales au sein d’un atelier théâtre

Les activités proposées aux personnes déficientes subissent des transformations structurelles : longtemps cloisonnées, elles étaient pensées et organisées dans une logique différentielle. Elles se conçoivent et se déroulent désormais dans un contexte de mixité réunissant personnes déficientes et non déficientes. À partir d’observations et d’entretiens réalisés auprès d’une jeune adolescente trisomique participant à un atelier théâtre, nous tentons d’analyser cette mixité pour mettre en lumière sa valeur d’intégration.Activities for people with disabilities are undergoing structural changes. For a long time they were compartmentalised, and were conceived and organised on differential lines. Now they are conceived and take place in a mixed context bringing together people with and without disabilities. Based on observations and interviews conducted with a young adolescent with Down’s Syndrome who was participating in a theatre workshop, we try to analyse the nature of this mixing in order highlight its integrative value