319 research outputs found

    Review of The Magical World of the Inklings

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    Review of Gareth Knight, The Magical World of the Inklings (Cheltenham, 2010). $24.99. 304 pages. ISBN: 9781908011015 New and expanded edition, first published in 199

    Tolkien\u27s Cosmology: Divine Beings and Middle-earth (2020) by Sam McBride

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    Book review by Matthew Dickerson of Tolkien\u27s Cosmology: Divine Beings and Middle-earth (2020) by Sam McBrid

    Review of The Magician’s Twin: C. S. Lewis on Science, Scientism, and Society

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    Review of John G. West, ed., The Magician’s Twin: C. S. Lewis on Science, Scientism, and Society (Seattle, 2012). 350 pages. $21.44. ISBN 9781936599059

    PROTEIN BASED BIOMIMETIC APPROACHS TO SURFACE HEMOCOMPATIBILITY AND BIOCOMPATIBILITY ENHANCEMENT

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    T. pallidum can survive a primary immune response and continue growing in the host for an extended period of time. T. pallidum is thought to bind serum fibronectin (FN) through Tp0483 on the surface to obscure antigens. A Tp0483 fragment (rTp0483) was adsorbed onto functionalized self-assembled monolayers (SAMs) with FN. FN capture by adsorbed rTp0483 depended greatly on surface chemistry with COO- groups being best for FN binding. Hemocompatibility was determined by analysis of plasma protein adsorption, intrinsic pathway activation, and platelet activation. rTp0483+FN bound an equal or lesser amount of fibrinogen (Fg), human serum albumin (HSA), and factor XII (FXII) compared to rTp0483 or FN alone and adsorption of rTp0483 prior to FN greatly decreased platelet activation. Inhibition of protein binding and platelet activation suggested an attenuated hematological response. Biocompatibility of rTp0483 and FN coated surfaces was characterized by macrophage uptake of protein coated polystyrene microspheres (PSMs), macrophage adsorption onto protein coated surfaces, cytotoxic effects of adsorbed rTp0483 and FN, and TNF-α and NO2- release in macrophages stimulated with rTp0483 and FN adsorbed and in solution. Addition of FN to rTp0483 on plain and COO- PSMs reduced phagocytosis compared to rTp0483 alone and on plain PSMs compared to FN alone. On plain PSMs addition of FN to adsorbed rTp0483 decreased TNF-α generation. Adsorption of rTp0483 before FN on large, flat COO- surfaces decreased macrophage adsorption and TNF-α and NO2- generation. High concentrations of rTp0483 were mildly cytotoxic to macrophages. FN binding by Tp0483 on T. pallidum likely plays a role in antigenic disguise and rTp0483+FN coatings may potentially inhibit FN and rTp0483 specific interactions with macrophages. Molecularly imprinted polymer coatings were also examined for biomaterial development. Fouling resistant 2-methacryloyloxyethyl phosphorylcholine (MPC) was imprinted with bovine serum albumin (BSA) protein templates to facilitate BSA specific binding. The BSA template was constructed and verified and BSA specific binding quantified using quartz crystal microbalance (QCM) and enzyme linked immunosorbent assay (ELISA). BSA imprinted coatings were determined to bind significantly more BSA than nonfouling MPC controls demonstrating the feasibility of targeted protein capture

    CuAAC for inorganic preceramic polymer synthesis

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    Ents, Elves, and Eriador: The Environmental Vision of J.R.R. Tolkien

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    Many readers drawn into the heroic tales of J. R. R. Tolkien’s imaginary world of Middle-earth have given little conscious thought to the importance of the land itself in his stories or to the vital roles played by the flora and fauna of that land. As a result, The Hobbit, The Lord of the Rings, and The Silmarillion are rarely considered to be works of environmental literature or mentioned together with such authors as John Muir, Rachel Carson, or Aldo Leopold. Tolkien’s works do not express an activist agenda; instead, his environmentalism is expressed in the form of literary fiction. Nonetheless, Tolkien’s vision of nature is as passionate and has had as profound an influence on his readers as that of many contemporary environmental writers. The burgeoning field of agrarianism provides new insights into Tolkien’s view of the natural world and environmental responsibility. In Ents, Elves, and Eriador, Matthew Dickerson and Jonathan Evans show how Tolkien anticipated some of the tenets of modern environmentalism in the imagined world of Middle-earth and the races with which it is peopled. The philosophical foundations that define Tolkien’s environmentalism, as well as the practical outworking of these philosophies, are found throughout his work. Agrarianism is evident in the pastoral lifestyle and sustainable agriculture of the Hobbits, as they harmoniously cultivate the land for food and goods. The Elves practice aesthetic, sustainable horticulture as they shape their forest environs into an elaborate garden. To complete Tolkien’s vision, the Ents of Fangorn Forest represent what Dickerson and Evans label feraculture, which seeks to preserve wilderness in its natural form. Unlike the Entwives, who are described as cultivating food in tame gardens, the Ents risk eventual extinction for their beliefs. These ecological philosophies reflect an aspect of Christian stewardship rooted in Tolkien’s Catholic faith. Dickerson and Evans define it as “stewardship of the kind modeled by Gandalf,” a stewardship that nurtures the land rather than exploiting its life-sustaining capacities to the point of exhaustion. Gandalfian stewardship is at odds with the forces of greed exemplified by Sauron and Saruman, who, with their lust for power, ruin the land they inhabit, serving as a dire warning of what comes to pass when stewardly care is corrupted or ignored. Dickerson and Evans examine Tolkien’s major works as well as his lesser-known stories and essays, comparing his writing to that of the most important naturalists of the past century. A vital contribution to environmental literature and an essential addition to Tolkien scholarship, Ents, Elves, and Eriador offers both Tolkien fans and environmentalists an understanding of Middle-earth that has profound implications for environmental stewardship in the present and the future of our own world. Matthew Dickerson, professor and member of the environmental studies program at Middlebury College, is the author or coauthor of several books, including Following Gandalf: Epic Battles and Moral Victory in The Lord of the Rings and From Homer to Harry Potter: A Handbook on Myth and Fantasy. Jonathan Evans, associate professor of English and director of the medieval studies program at the University of Georgia, is a member of the Environmental Ethics Certificate Program faculty. His essays on J. R. R. Tolkien have been published in J. R. R. Tolkien and His Literary Resonances, Tolkien the Medievalist, and The J. R. R. Tolkien Encyclopedia. Anyone who ever thrilled to Tolkien\u27s fighting trees, or to the earthy Tom Bombadil, or to the novel charm of the Shire will want to read this important and lovely book. --Bill McKibben, Scholar in Residence in Environmental Studies, Middlebury College The writing style is engaging, and the book presents the first fully developed study of Tolkien and the environment at the same time that it offers insights into a range of Tolkien\u27s major and minor works. --Choice A fascinating ecocritical evaluation of the writings of J.R.R. Tolkien. Valuable for both Tolkien fans and those interested in ecocriticism and environmental literature. Especially useful given the popularity of the subject matter. --Northeastern Naturalist This book is a major new contribution to the subject of Tolkien\u27s work in relation to the natural world and environmentalism. . . . The authors have devised an ingenious and useful distinction between agriculture for food (the domain of the Hobbits), horticulture for aesthetic beauty (that of Elves), and feraculture . . . for wilderness preservation (Ents). --Tolkien Studies Dickerson and Evans\u27s ecological thesis has one outstanding merit, which is that Tolkien himself would have recognized and thoroughly approved of what they have to say. --Tom Shippey, from the Afterword Reading a non-fiction book about Tolkien\u27s environmental vision may seem like a way to spoil the sheer fun of reading The Lord of the Rings and his other books. What I found as I read this book was that I wanted to reread every word of Tolkien to see for myself what the authors have given a glimpse of. This book is for everyone who loves the work of J.R..R. Tolkien, and who loves the world around them. --Armchair Interviews “The two authors are unabashed in their effort to use the lure of Tolkien to draw readers to the Green movement. The book constitutes an unorthodox yet largely successful combination of scholarly reading and political manifesto. Dickerson and Evans seek to rouse Tolkien fans to scour their own Shires before it is too late and Mordor triumphs.”--Seven “A well-researched, readable, and relevant study of Tolkien’s ecological principles and concerns. And, as Tom Shippey comments in the afterword, Tolkien, no doubt, would approve.”—Journal of the Fantastic in the Arts This volume is a thorough and welcome explication of Tolkien’s vision of the natural world, and of the ways in which that vision is applicable to our own lives today. --Interdisciplinary Studies in Literature & the Environment Ents, Elves, and Eriador should...be praised for drawing attention to the multifaceted portrayal of the natural world in Tolkien’s work. --Folklore It is an enjoyable and intellectually valuable read for its detailed examination of the landscape cultures of Middle-earth and their liminal overlapping of one another. --Studies in Medieval & Renaissnace Teaching “Does much to show why Tolkein should be recognized as one of those who laid the foundations for and formed the environmental movement as we know it today.”--Mallorn Dickerson and Evans provide a valuable discussion of concepts of stewardship as figured by Gandalf, Treebeard, Sam, Galadriel, and various kings and leaders, and how such examples bridge our inner world of fantasy and what we think of as the outer world of reality. --Studies in Medieval and Renaissance Teaching A fine introduction to Tolkein\u27s environmental achievement. --Flourish Book Reviewhttps://uknowledge.uky.edu/upk_environmental_sciences/1005/thumbnail.jp

    Phase-Field Model of Silicon Carbide Growth During Isothermal Condition

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    Silicon carbide (SiC) emerges as a promising ceramic material for high-temperature structural applications, especially within the aerospace sector. The utilization of SiC-based ceramic matrix composites (CMCs) instead of superalloys in components like engine shrouds, combustors, and nozzles offers notable advantages, including a 25% improvement in fuel efficiency, over 10% enhanced thrust, and the capability to withstand up to 500∘^{\circ}C higher operating temperatures. Employing a CALPHAD-reinforced multi-phase-field model, our study delves into the evolution of the SiC layer under isothermal solidification conditions. By modeling the growth of SiC between liquid Si and solid C at 1450∘^{\circ}C, we compared results with experimental microstructures and quantitatively examined the evolution of SiC thickness over time. Efficient sampling across the entire model space mitigated uncertainty in high-temperature kinetic parameters, allowing us to predict a range of growth rates and morphologies for the SiC layer. The model accounts for parameter uncertainty stemming from limited experimental knowledge and successfully predicts relevant morphologies for the system. Experimental results validated the kinetic parameters of the simulations, offering valuable insights and potential constraints on the reaction kinetics. We further explored the significance of multi-phase-field model parameters on two key outputs, and found that the diffusion coefficient of liquid Si emerges as the most crucial parameter significantly impacting the SiC average layer thickness and grain count over time. This study provides valuable insights into the microstructure evolution of the Si-C binary system, offering pertinent information for the engineering of CMCs in industrial applications
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