Role of medial premotor areas in action language processing in relation to motor skills

The literature reports that the supplementary motor area (SMA) and pre-supplementary motor area (pre-SMA) are involved in motor planning and execution, and in motor-related cognitive functions such as motor imagery. However, their specific role in action language processing remains unclear. In the present study, we investigated the impact of repetitive transcranial magnetic stimulation (rTMS) over SMA and pre-SMA during an action semantic analogy task (SAT) in relation with fine motor skills (i.e., manual dexterity) and motor imagery abilities in healthy non-expert adults. The impact of rTMS over SMA (but not pre-SMA) on reaction times (RT) during SAT was correlated with manual dexterity. Specifically, results show that rTMS over SMA modulated RT for those with lower dexterity skills. Our results therefore demonstrate a causal involvement of SMA in action language processing, as well as the existence of inter-individual differences in this involvement. We discuss these findings in light of neurolinguistic theories of language processing

The use of executive fluency tasks to detect cognitive impairment in individuals with subjective cognitive decline

Objective: Although evidence has indicated that subjective cognitive decline (SCD) may be an early sign of Alzheimer’s disease (AD), the objectification of cognitive impairment in SCD is challenging, mainly due to the lack of sensitivity in assessment tools. The present study investigated the potential contribution of two verbal fluency tasks with high executive processing loads to the identification of cognitive impairment in SCD. Methods: A total of 60 adults with SCD and 60 healthy controls (HCs) performed one free action (verb) fluency task and two fluency tasks with more executive processing load—an alternating fluency task and an orthographic constraint fluency task—and the results were compared. Result: In the free action fluency task, the performance of the participants with SCD and the HCs was similar. However, HCs performed significantly better than SCD in the alternating fluency task, which required mental flexibility, and the orthographic constraint fluency task, which required inhibition. Discussion: The study findings suggest that verbal fluency tasks with high executive processing load could be useful in detecting cognitive deficits at the preclinical stage of AD. The inclusion of such tests in assessment batteries should be considered in order to improve the detection of subtle cognitive impairment in preclinical major neurocognitive disorder populations

Experimental evaluation of UWB indoor positioning for indoor track cycling

Accurate radio frequency (RF)-based indoor localization systems are more and more applied during sports. The most accurate RF-based localization systems use ultra-wideband (UWB) technology; this is why this technology is the most prevalent. UWB positioning systems allow for an in-depth analysis of the performance of athletes during training and competition. There is no research available that investigates the feasibility of UWB technology for indoor track cycling. In this paper, we investigate the optimal position to mount the UWB hardware for that specific use case. Different positions on the bicycle and cyclist were evaluated based on accuracy, received power level, line-of-sight, maximum communication range, and comfort. Next to this, the energy consumption of our UWB system was evaluated. We found that the optimal hardware position was the lower back, with a median ranging error of 22 cm (infrastructure hardware placed at 2.3 m). The energy consumption of our UWB system is also taken into account. Applied to our setup with the hardware mounted at the lower back, the maximum communication range varies between 32.6 m and 43.8 m. This shows that UWB localization systems are suitable for indoor positioning of track cyclists

Wi-PoS : a low-cost, open source ultra-wideband (UWB) hardware platform with long range sub-GHz backbone

Ultra-wideband (UWB) localization is one of the most promising approaches for indoor localization due to its accurate positioning capabilities, immunity against multipath fading, and excellent resilience against narrowband interference. However, UWB researchers are currently limited by the small amount of feasible open source hardware that is publicly available. We developed a new open source hardware platform, Wi-PoS, for precise UWB localization based on Decawave’s DW1000 UWB transceiver with several unique features: support of both long-range sub-GHz and 2.4 GHz back-end communication between nodes, flexible interfacing with external UWB antennas, and an easy implementation of the MAC layer with the Time-Annotated Instruction Set Computer (TAISC) framework. Both hardware and software are open source and all parameters of the UWB ranging can be adjusted, calibrated, and analyzed. This paper explains the main specifications of the hardware platform, illustrates design decisions, and evaluates the performance of the board in terms of range, accuracy, and energy consumption. The accuracy of the ranging system was below 10 cm in an indoor lab environment at distances up to 5 m, and accuracy smaller than 5 cm was obtained at 50 and 75 m in an outdoor environment. A theoretical model was derived for predicting the path loss and the influence of the most important ground reflection. At the same time, the average energy consumption of the hardware was very low with only 81 mA for a tag node and 63 mA for the active anchor nodes, permitting the system to run for several days on a mobile battery pack and allowing easy and fast deployment on sites without an accessible power supply or backbone network. The UWB hardware platform demonstrated flexibility, easy installation, and low power consumption

Normative data for phonemic and semantic verbal fluency test in the adult french-Quebec population and validation study in Alzheimer's disease and depression

Objective: Verbal fluency tasks are principally used to assess lexical access and have shown usefulness for differential diagnosis. The purpose of Study 1 was to provide normative data in the adult French–Quebec population (Canada) for semantic verbal fluency (animals), for two sets of phonemic verbal fluency (TNP and PFL), and for letter P alone (60 seconds per category/letter). The objectives of Study 2 were to establish the diagnostic and predictive validity of the present tasks and normative data in Alzheimer’s disease (AD) and major depressive episode (MDE). Method: The normative sample consisted of 932 participants aged 19–91 years. Based on multiple linear regressions, equations to calculate Z-scores were provided. To assess validity, performance of 62 healthy participants was compared to 62 participants with AD and 41 with MDE aged over 50. Results: Age and education, but not gender, predicted performance on each verbal fluency task. Healthy adults aged 50 and younger had a better performance on semantic than phonemic verbal fluency. In comparison to MDE, AD participants had lower performance on animals and TNP, but not on letter P. Ninety percent of people with a Z-score ≤ −1.50 on semantic verbal fluency had AD and the global accuracy was 76.6%. Test–retest reliability over one year was high for both animals (r = .711) and TNP (r = .790) in healthy older participants, but dropped for animals in people with AD (r = .493). Conclusions: These data will strengthen accurate detection of verbal fluency deficits in French–Quebec adults