Impact of Light Higgs Properties on the Determination of tan⁡β\tan\beta and msusym_{susy}

We examine whether parameters related to the Higgs sector of the minimal supersymmetric standard model can be determined by detailed study of the production cross section and decay branching ratios of the Higgs boson. Assuming that only the light Higgs boson will be observed at a future $e^+e^-$ linear collider with $\sqrt{s}=300\sim500$ GeV, we show that values of $m_{susy}$ and $\tan\beta$ are restricted within a narrow region in the $m_{susy}$ versus $\tan\beta$ plane by the combined analysis of the light Higgs properties. It is also pointed out that, in some case, $\tan\beta$ may be restricted to a relatively small value, $\tan\beta=1\sim5$.Comment: 7 pages with 10 figures, to be published in Prog. Theor. Phy

Prospects of Measuring General Higgs Couplings at e^+e^- Linear Colliders

We examine how accurately the general HZV couplings, with V=Z,gamma, may be determined by studying e^+e^- --> Hff-bar processes at future e^+e^- linear colliders. By using the optimal-observable method, which makes use of all available experimental information, we find out which combinations of the various HZV coupling terms may be constrained most efficiently with high luminosity. We also assess the benefits of measuring the tau-lepton helicities, identifying the bottom-hadron charges, polarizing the electron beam and running at two different collider energies. The HZZ couplings are generally found to be well constrained, even without these options, while the HZ-gamma couplings are not. The constraints on the latter may be significantly improved by beam polarization.Comment: 28 pages (LaTeX), 5 figures (axodraw and eps

Organelle Interplay - Peroxisome Interactions in Health and Disease

This is the author accepted manuscript. The final version is available from Wiley via the DOI in this record.Peroxisomes are multifunctional, dynamic, membrane‐bound organelles with important functions in cellular lipid metabolism, rendering them essential for human health and development. Important roles for peroxisomes in signaling and the fine‐tuning of cellular processes are emerging, which integrate them in a complex network of interacting cellular compartments. Like many other organelles, peroxisomes communicate through membrane contact sites. For example, peroxisomal growth, positioning, and lipid metabolism involves contacts with the endoplasmic reticulum (ER). Here, we discuss the most recent findings on peroxisome‐organelle interactions including peroxisome‐ER interplay at membrane contacts sites, and functional interplay with mitochondria, lysosomes, and lipid droplets in mammalian cells. We address tether proteins, metabolic cooperation, and the impact of peroxisome interactions on human health and disease.Biotechnology & Biological Sciences Research Council (BBSRC)Medical Research Council (MRC)University of ExeterGerman Research FoundationUniversity of Heidelber