Ballistic Coalescence Model

We study statistical properties of a one dimensional infinite system of coalescing particles. Each particle moves with constant velocity $\pm v$ towards its closest neighbor and merges with it upon collision. We propose a mean-field theory that confirms a $t^{-1}$ concentration decay obtained in simulations and provides qualitative description for the densities of growing, constant, and shrinking inter-particle gaps.Comment: 4 pages, 2 column Revtex, 5 figures include

Lattice Boltzmann method for viscoelastic fluids

Lattice Boltzmann model for viscoelastic flow simulation is proposed; elastic effects are taken into account in the framework of Maxwell model. The following three examples are studied using the proposed approach: a transverse velocity autocorrelation function for free evolving system with random initial velocities, a boundary-driven propagating shear waves, and a resonant enhancement of oscillations in a periodically driven fluid in a capillary. The measured shear wave dispersion relation is found to be in a good agreement with the theoretical one derived for the Navier-Stokes equation with the Maxwell viscoelastic term.Comment: 4 pages, 5 figure

A model for the self-organization of vesicular flux and protein distributions in the Golgi apparatus

The generation of two non-identical membrane compartments via exchange of vesicles is considered to require two types of vesicles specified by distinct cytosolic coats that selectively recruit cargo and two membrane-bound SNARE pairs that specify fusion and differ in their affinities for each type of vesicles. The mammalian Golgi complex is composed of 6-8 non-identical cisternae that undergo gradual maturation and replacement yet features only two SNARE pairs. We present a model that explains how the distinct composition of Golgi cisternae can be generated with two and even a single SNARE pair and one vesicle coat. A decay of active SNARE concentration in aging cisternae provides the seed for a cis > trans SNARE gradient that generates the predominantly retrograde vesicle flux which further enhances the gradient. This flux in turn yields the observed inhomogeneous steady-state distribution of Golgi enzymes, which compete with each other and with the SNAREs for incorporation into transport vesicles. We show analytically that the steady state SNARE concentration decays exponentially with the cisterna number. Numerical solutions of rate equations reproduce the experimentally observed SNARE gradients, overlapping enzyme peaks in cis, medial and trans and the reported change in vesicle nature across Golgi: Vesicles originating from younger cisternae mostly contain Golgi enzymes and SNAREs enriched in these cisternae and extensively recycle through the Endoplasmic Reticulum (ER), while the other subpopulation of vesicles contains Golgi proteins prevalent in older cisternae and hardly reaches the ER.Comment: 15 pages, 6 figure