921 research outputs found
FAA versus the Magnuson - Moss Warranty Act: Which Warrants Precedence, The
These questions have proven to be a formidable foe for the judiciary. Moreover, courts and commentators have been divided as to what answer will produce the best policy. In 2002, the discussion seemed to be headed toward conclusion after the Fifth and Eleventh Circuits found that the FAA should trump the MMWA in the event of statutory conflict. However, with the Ninth Circuit’s decision in Kolev v. Euromotors West/The Auto Gallery, this polarizing issue has once again become a focus in American jurisprudence. While the Ninth Circuit has recently withdrawn Kolev sua sponte, it is doubtful that the Ninth Circuit is abandoning the issue as it has delayed subsequent submissions of Kolev until the California Supreme Court delivers its decision in Sanchez v. Valencia Holding Co., LLC. Thus, an understanding of Kolev is vital to grasping both the current and future landscape of MMWA arbitrability. This paper asserts that not only is Kolev’s legal reasoning inaccurate, but its policy manifestations would have been flawed as well
Adhesion plaque protein, talin, is phosphorylated in vivo in chicken embryo fibroblasts exposed to the tumor-promoting phorbol ester
Journal ArticleTalin is a high molecular weight phosphoprotein that is localized at adhesion plaques. We have found that talin phosphorylation increases 3.0-fold upon exposure of chicken embryo fibroblasts to the tumor-promoting phorbol ester, phorbol 12-myristate 13-acetate
The Lifetime Experiences of Being Labeled “Gifted”: Case Studies of Adults Who Participated in a 1959 Public School Gifted Program
The purpose of the study was to explore the current perceptions of adults who were enrolled in the gifted program of the St. Louis Public Schools in the fall of 1959 or spring of 1960. At this time in history the Cold War was a reality and the U.S. enacted the National Defense Education Act (NDEA) to find talented young people and give them the opportunity to excel academically. The program in this research was already in place when the NDEA was put into effect. A pool of 62 potential subjects was identified and 33 accepted the invitation to participate. The research question was, “How did the St. Louis Public Schools gifted program contribute to the lived experience of the students who started in the program in 1959 and 1960?” A multiple case study method was determined to be the best fit for this study. Interviews were conducted in person, by telephone or by e-mail. From the interview transcriptions, the story of each case contributed to a bigger story of all the cases. After completing the interviews and data analysis, seven themes emerged: expectations, social, label, spiritual/religious, impact, lack of high school support, and lifetime well-being. Another significant finding was that approximately 90% graduated college with at least a two-year degree at a time when less than 52% of high school graduates even attended college, albeit the enriching primary school pull-out program experience was followed by a less-than-enriching secondary school experience that lacked academic and college advising. The participants had an overall positive opinion of their lived experience of being labeled gifted. The most salient finding was their life satisfaction, with an implication that positive labeling and a subsequent self-fulfilling prophesy contributed to it. Further iii research should be conducted on the relationship between positive labeling and life satisfaction with students not identified as gifted
Low-cost Sensor Glove with Force Feedback for Learning from Demonstrations using Probabilistic Trajectory Representations
Sensor gloves are popular input devices for a large variety of applications
including health monitoring, control of music instruments, learning sign
language, dexterous computer interfaces, and tele-operating robot hands. Many
commercial products as well as low-cost open source projects have been
developed. We discuss here how low-cost (approx. 250 EUROs) sensor gloves with
force feedback can be build, provide an open source software interface for
Matlab and present first results in learning object manipulation skills through
imitation learning on the humanoid robot iCub.Comment: 3 pages, 3 figures. Workshop paper of the International Conference on
Robotics and Automation (ICRA 2015
CRP1, a LIM domain protein implicated in muscle differentiation, interacts with α-actinin
Journal ArticleMembers of the cysteine-rich protein (CRP) family are LIM domain proteins that have been implicated in muscle differentiation. One strategy for defining the mechanism by which CRPs potentiate myogenesis is to characterize the repertoire of CRP binding partners
Conserved LIM protein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegans
Journal ArticleWe describe here the molecular and functional characterization of the Caenorhabditis elegans unc-97 gene, whose gene product constitutes a novel component of muscular adherens junctions. UNC-97 and homologues from several other species define the PINCH family, a family of LIM proteins whose modular composition of five LIM domains implicates them as potential adapter molecules
Characterization of the interaction between zyxin and members of the Ena/Vasodilator-stimulated Phosphoprotein family of proteins
Journal ArticleZyxin contains a proline-rich N-terminal domain that is similar to the C-terminal domain in the ActA protein of the bacteria, Listeria monocytogenes. We screened the entire amino acid sequence of human zyxin for Menainteracting peptides and found that, as with ActA, proline-rich sequences were the sole zyxin sequences capable of binding to Ena/vasodilator-stimulated phosphoprotein (VASP) family members in vitro
Molecular characterization of human zyxin
Journal ArticleZyxin is a component of adhesion plaques that has been suggested to perform regulatory functions at these specialized regions of the plasma membrane. Here we describe the isolation and characterization of cDNAs encoding human and mouse zyxin
Cytoskeleton-associated PDZ-LIM protein, ALP, acts on serum response factor activity to regulate muscle differentiation
Journal ArticleIn this report, an antisense RNA strategy has allowed us to show that disruption of ALP expression affects the expression of the muscle transcription factors myogenin and MyoD, resulting in the inhibition of muscle differentiation. Introduction of a MyoD expression construct into ALP-antisense cells is sufficient to restore the capacity of the cells to differentiate, illustrating that ALP function occurs upstream of MyoD
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