226 research outputs found

    Unlocking the Potential of Public Libraries in Supporting Distance Learning

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    This paper examines the place of public libraries in supporting distance learners in Makerere University, exploring the factors which affect utilisation of their services. The study adopted a survey design with 300 B.Ed. students, collecting data through focus group discussions, structured questionnaires and individual interviews

    Assuring the Quality of Teaching at Makerere University in Uganda: Practices and Experiences of Academics and Students

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    Quality is an ethos in academia and assuring it is top of the agenda at many universities. Since the 1990s, substantial research has been conducted on the quality assurance systems of developed countries with advanced higher education systems. However, literature on quality assurance systems in the context of Sub-Saharan Africa is limited. The study examined the practices and experiences of stakeholders at the student-academic interface in assuring the quality of teaching at Makerere University. A case study design was employed and respondents included academics and final-year students. Data was collected through documents review, interviews and focus group discussions. Thematic analysis and content analysis were used to analyse the data. The findings demonstrate that the university employs five practices to assure the quality of teaching, namely, recognition of teaching, student evaluation of teaching, pedagogical training, monitoring and supervision of teaching, competence-based deployment and interfacing. The findings further show that stakeholders had varying experiences of teaching quality assurance practices

    The progress of AAV-mediated gene therapy in neuromuscular disorders

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    INTRODUCTION: The well-defined genetic causes and monogenetic nature of many neuromuscular disorders, including Duchenne muscular dystrophy (DMD) and spinal muscular atrophy (SMA), present gene therapy as a prominent therapeutic approach. The novel variants of adeno-associated virus (AAV) can achieve satisfactory transduction efficiency of exogenous genes through the central nervous system and body-wide in skeletal muscle. AREAS COVERED: In this review, we summarize the strategies of AAV gene therapy that are currently under preclinical and clinical evaluation for the treatment of degenerative neuromuscular disorders, with a focus on diseases such as DMD and SMA. In addition to gene replacement strategy, we provide an overview of other approaches such as AAV-mediated RNA therapy and gene editing in the treatment of muscular dystrophies. EXPERT OPINION: AAV gene therapy has achieved striking therapeutic efficacy in clinical trials in infants with SMA. Promising results have also come from the preclinical studies in small and large animal models of DMD and several clinical trials are now on the way. This strategy shows great potential as a therapy for various neuromuscular disorders. Further studies are still required to confirm its long-term safety and improve the efficacy

    Il dialogo interreligioso e la questione della verità

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    In this article, I approach the question of truth in the interreligious dialogue. The contribution is divided into three sections. In the first, I clarify what I mean by “dialogue” and by “interreligious dialogue” from a philosophical point of view. In the second, I address some problems relating to religious disagreement and reflect on what allows the question of truth to be maintained within the interreligious dialogue. In the third, I argue that, given certain conditions, an apologetic attitude is not only possible but necessary within the interreligious dialogue. The general thesis that I intend to support is that the question of truth is crucial to interreligious dialogue
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