The Role of Aeromonas in Diarrhea: a Review

Abstract : The evidence for an enteropathogenic role of Aeromonas spp. is still controversial. This review examines various parameters related to a causative role of Aeromonas and concludes that infraspecific subsets of strains with a particular array of enterotoxin genes are potential enteropathogens. The consequences for stool bacteriology are discusse

Endocarditis due to nonfermentative gram-negative rods. An updated review

This review covers endocarditis due to Pseudomonas aeruginosa, P. maltophilia (9 cases), P. cepacia (16 cases), Acinetobacter calcoaceticus (20 cases), Moraxella spp. (6 cases), and other nonfermenters. Such endocarditis cases are very rare and occur chiefly in the setting of drug addiction, on prosthetic or on previously damaged valve

How to measure patent thickets – a novel approach

The existing literature identifies patent thickets indirectly. In this paper we propose a novel measure based on patent citations which allows us to measure the density of patent thickets directly. We discuss the algorithm which generates the measure and present descriptive results validating it. Moreover, we identify technology areas which are particularly impacted by patent thickets

Fleroxacin (Ro 23-6240): activity in virtro against 355 enteropathogenic and non-fermentative Gram-negative bacilli and Legionella pneumophila

The antibacterial activity of fleroxacin (Ro 23-6240, AM-833), a new 6-fluoroquinolone, was determined against 149 strains of enteropathogenic bacteria (17 species) and 191 strains (28 species) of glucose non-fermentative Gram-negative rods (excluding Pseudomonas aeruginosa), and against 15 strains of Legionella pneumophila. The cumulative susceptibility of these groups of bacteria to Ro 23-6240 at the 2 mg/l level were 99.2% 80.1 and 100% of tested strains, respectivel

The European Patent System: A Descriptive Analysis

The European Patent System consists of national patent offices (NPOs) and the supranational European Patent Office (EPO). EPO and the NPOs have granted patents in Europe side-by-side since 1980. The resulting patent system is complicated and less coordinated than might be expected. Firms must consider a number of variables when selecting the route of patenting they take within this system: price, rigour of examination, duration of examination, quality of legal redress. To date there is little descriptive evidence on how firms choose between EPO and national offices. This paper provides a rich descriptive analysis of patenting in Europe. We analyze how origin, size and technological focus of companies, affect how they choose among patent offices within the EPS and report differences in examination durations and grant rates across patent offices

Turicella otitidis and Corynebacterium auris: 20years on

Turicella otitidis and Corynebacterium auris, described as new species 20years ago, have been isolated mainly from the external ear canal and middle ear fluid. While their taxonomic position has been clearly established, their diagnosis in the routine laboratory is difficult. The question of their pathogenic potential in otitis is still open but might be elucidated better if corynebacteria are speciated more often