38 research outputs found

    The Anticaries Effect of a Food Extract (Shiitake) in a Short-Term Clinical Study

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    The main objective was to investigate whether low-molecular-weight fraction of edible mushroom shiitake extract (Lentinus edodes) possesses caries-preventive properties. The study was designed as a double-blind, three-leg, cross-over, randomized, controlled clinical trial carried out on two series of volunteers at the University of Gothenburg, and the Academic Centre for Dentistry Amsterdam. Volunteers rinsed twice daily with a solution containing low-molecular-weight fraction of edible mushroom, placebo (negative control without active ingredients), or Meridol (positive control, AmF-SnF2) for two weeks, with a two-week washout period between each rinsing period. Changes in the acidogenicity of dental plaque before and after a sucrose challenge, shifts in microbial composition, and plaque scores were determined. Frequent rinses with shiitake reduced the metabolic activity of dental plaque. No reduction of plaque scores and no inhibition of the production of organic acids in plaque was found. Minor differences in microbial composition between test sessions were found. To conclude, the results indicate that shiitake extract has anticariogenic potential, but not to the same extent as the positive control

    Aerosol in the oral health-care setting:a misty topic

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    Abstract: Studies have shown that mouth and respiratory tract microorganisms can be transported in aerosol and spatter. Due to aerosol-generating procedures, there are potentially various infection risks for patients and those working in health care, especially in oral health care. Dental aerosol can contaminate not only the mucous membranes of the oral health-care professional’s mouth, respiratory passages, and eyes but also exposed surfaces and materials in the environment. As such, preventing disease transmission within oral health-care offices is important issue. Since the start of the COVID-19 pandemic, an innumerable amount of (mis)information and advice on how to stay safe and prevent the spread of coronavirus has been published. What preventive measures can and have been taken to counteract this, and what have we learned during the pandemic? This review summarizes relevant literature that has addressed the presence and dispersal of aerosol and spatter as a concern in health care. It includes the sources of dental aerosol, their potential health threats, and strategies for controlling and mitigating their impact. It shows that further research is needed to better understand the potential health risks of dental aerosol and to develop effective strategies for mitigating them. Clinical relevance: Using personal protective equipment, high-volume evacuation systems and pre-procedural antimicrobial agents can help to reduce the potential for infection in oral health-care settings and protect the well-being of oral health-care workers and their patients.</p

    Can Chemical Mouthwash Agents Achieve Plaque/Gingivitis Control?

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    Can chemical mouthwash agents achieve plaque/gingivitis control? van der Weijden, G.A.; van der Sluijs, E.; Ciancio, S.G.; Slot, D.E. Published in: The Dental Clinics of North America DOI: 10.1016/j.cden.2015.06.002 Link to publication Citation for published version (APA): van der Weijden, F. A., Van der Sluijs, E., Ciancio, S. G., &amp; Slot, D. E. (2015). Can chemical mouthwash agents achieve plaque/gingivitis control? The Dental Clinics of North America, 59(4), 799-829. https://doi.org/10.1016/j.cden.2015.06.002 General rights It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: https://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. KEY POINTS Oral health is important since the mouth is the gateway to the human body. Bacteria are always present in the oral cavity and when not frequently removed the dental plaque biofilm leads to the development of oral disease. Over the past decades, the use of mouthwashes has become customary, usually following mechanical plaque biofilm control. Although people in industrialized countries use various oral hygiene products with the expectation of an oral health benefit, it is important that sufficient scientific evidence exists to support such claims. This meta-review summarized and appraised the current state of evidence that was based on systematic reviews, with respect to the efficacy of various active ingredients of overthe-counter chemotherapeutic mouthwash formulations for plaque control and managing gingivitis. Evidence suggests that a mouthwash containing chlorhexidine (CHX) is the first choice. The most reliable alternative for plaque control is essential oil (EO). No difference between CHX and EO with respect to gingivitis was observed. Dent Clin N Am 59 (2015) 799-829 http://d

    Implant-abutment emergence angle and profile in relation to peri-implantitis: A systematic review

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    Statement: The aim of this systematic review is to analyze literature regarding the relationship between the implant-abutment emergence angle (EA) and implant emergence profile (EP) and the prevalence of peri-implantitis. Methods: PubMed and the Cochrane Library were searched for studies from initiation up to April 2022. Studies describing the EA and EP in association with peri-implantitis were considered eligible for this review and selected for inclusion in this review if implant groups with wide and narrow EA and different EP types were described. Results: Searches in PubMed and the Cochrane Library led to 1116 unique titles and the inclusion of three studies. These concerned 168–349 implants. Two studies presented the mean prevalence of peri-implantitis which was 16.7% and 24.8% at the implant level. Both studies showed a significant relationship between peri-implantitis in bone-level implant groups with an EA above 30° compared to implants with an EA below 30°. A third study presented marginal bone loss which tended to be smaller when the EA was around 20°–40°. In one of the three included studies, the prevalence of peri-implantitis was significantly higher if implants had a convex EP compared to a concave or straight EP. Another study showed a significantly higher prevalence of peri-implantitis in implants with a convex EP compared to other EP types, if combined with an EA above 30°. Conclusions: Three eligible studies were found. Reported associations should therefore be considered with caution. Synthesis suggests an association between a larger EA (>30°) and a higher prevalence of peri-implantitis or marginal bone loss compared to a smaller EA (<30°). A convex EP may also be associated with a higher prevalence of peri-implantitis. However, causality remains a question

    Bone remodeling around dental implants after 1–1.5 years of functional loading: A retrospective analysis of two-stage implants

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    Objectives: This study aims to retrospectively assess to what extent peri-implant bone level changes occur from exposing the implant to the oral environment at the second stage of surgery (SSS) to the baseline assessment and, additionally, after 1–1.5 years of functional loading. Further, this study aims to examine the role of the emergence angle in marginal bone changes. Material and Methods: This retrospective study included 46 patients treated between 2012 and 2019. These patients received 64 bone-level dental implants. After implant placement, SSS, and baseline assessment, relevant clinical peri-implant conditions and radiographical data were collected. A radiographic examination of the marginal bone level was performed after SSS, the baseline assessment, and 1–1.5 years of follow-up. Results: The peri-implant periodontal probing depth increased significantly from 3.08 ± 0.7 mm at the baseline to 3.27 ± 0.81 mm at the 1–1.5-year follow-up. The mean marginal bone level at the implant level was 0.12 ± 0.23, 0.35 ± 0.43, and 0.47 ± 0.47 mm at the SSS, baseline, and the 1–1.5-year follow-up, respectively. Most changes occurred at the implant's distal site. A significant relationship was found between the emergence angle and the extent of change in the marginal bone level between the SSS and baseline (r =.430, p ≤.001). Conclusions: Most changes in the marginal bone level occurred between SSS and baseline assessments. For diagnostic purposes, it is advised to obtain a standardized radiograph after SSS to monitor peri-implant bone-level alterations

    The effect on clinical parameters of periodontal inflammation following non-surgical periodontal therapy with ultrasonics and chemotherapeutic cooling solutions: a systematic review

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    Aim: To establish the added effect of a chemotherapeutic cooling solution in an ultrasonic device on clinical parameters of periodontal inflammation following non-surgical periodontal therapy. Methods: The MEDLINE-PubMed, Cochrane-CENTRAL, and the EMBASE databases were searched. Probing pocket depth (PPD) and clinical attachment level (CAL) and their changes were selected as outcome variables. Subgroup analyses were performed according to the following active ingredients: essential oils (EO), povidone–iodine (PVP), and chlorhexidine (CHX). Results: Screening of 100 unique papers resulted in 14 eligible publications, including 16 comparisons. The meta-analysis (MA) showed that when the ultrasonic cooling solution had adjuvant chemotherapeutic properties, the difference of means (DiffM) for end value PPD-0.12 (95% CI: −0.42; 0.18) and for CAL the DiffM+-0.13 (95% CI: −0.39; 0.14). None of these were statistically significant, and the findings were supported by the overall descriptive analysis. Subgroup analysis only revealed a small effect for PVP on the difference (DiffM = −0.23, 95% CI: −0.43; −0.02) with respect to CAL (p = 0.03). Conclusions: The collective evidence indicates that overall, no additional effects were observed. There is a “very weak” recommendation based on the sub-analysis showing that in conjunction with PVP, a very small gain in CAL may be expected. For the use of CHX or EO, the added effect can be considered to be “zero.” Therefore, the strength and direction of the recommendation emerging from this review is against their use

    The efficacy of powered toothbrushes: A systematic review and network meta-analysis

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    Aim: This systematic review and network meta-analysis synthesizes the available clinical evidence concerning efficacy with respect to plaque scores following a brushing action with oscillating-rotating (OR) or high-frequency sonic (HFS) powered toothbrushes (PTB) compared with a manual toothbrush (MTB) as control. Material and methods: Databases were searched up to 1 August 2021, for clinical trials that evaluated the efficacy of a PTB with OR or HFS technology compared with an MTB on plaque removal after a single-brushing action and conducted with healthy adult patients. Meta-analysis (MA) and a network meta-analysis (NMA) were performed. Results: Twenty-eight eligible publications, including 56 relevant comparisons, were retrieved. The overall NMA results for the mean post-brushing score showed a statistically significant difference for the comparison between an OR PTB and an MTB (SMD = −0.43; 95% CI [−0.696;−0.171]). The change in plaque score data showed a significant effect of a PTB over an MTB and OR over HFS. Based on ranking, the OR PTB was highest, followed by the HFS PTB and the MTB. Conclusion: Within the limitations of the present study design, based on the outcome following a single-brushing action, it can be concluded that for dental plaque removal, there is a high certainty for a small effect of a PTB over an MTB. This supports the recommendation to use a powered toothbrush for daily plaque removal. There is moderate certainty for a very small benefit for the use of a powered toothbrush with an OR over an HFS mode of action
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