The Effect of Statins and Other Cardiovascular Medication on Ischemia-Reperfusion Damage in a Human DIEP Flap Model: Theoretical and Epidemiological Considerations

Background. Statins and other cardiovascular medication possess antioxidant capacity. It was examined whether chronic use of these medications protects from the development of ischemia-reperfusion (I/R) related complications after DIEP (Deep Inferior Epigastric Perforator Free Flap) surgery. This paper contains a literature study on the antioxidant working mechanisms of these drugs. Methods. Medical information of 134 DIEP patients (173 flaps) was studied from their medical files. Patient and operative characteristics were registered, as well as I/R related complications. Results. Of the group that didnot use statins, 16.3% developed complications versus 30.8% amongst patients that did use these drugs (P = 0.29). Amongst patients that chronically use other cardiovascular medication, 26.8% developed I/R related complications versus 14.4% of the patients without medication (P = 0.10). Conclusions. Chronic use of statins or other cardiovascular medication didnot decrease the occurrence of I/R related complications after DIEP surgery. Therefore, research should be aimed at evaluating short-term pre-treatment with statins

Patrick-Murray Administration Celebrates Grand Opening of Old Colony Housing Development

<p>This case report presents the use of near-infrared fluorescence (NIRF) imaging using indocyanine green (ICG) and its potential for the evaluation of soft tissue viability in a traumatic case. Standard implementation of this novel imaging modality might decrease the number of surgical debridement procedures in complex traumatic wounds.</p

BUDH IES V:The baryonic Tully-Fisher relation at z = 0.2 based on direct H I detections

We present H I-based B- and R-band Tully-Fisher relations (TFRs) and the Baryonic TFR (BTFR) at z = 0.2 using direct H I detections from the Blind Ultra-Deep H I Environmental Survey (BUDH IES). Deep photometry from the Isaac Newton Telescope was used for 36 out of 166 H I sources, matching the quality criteria required for a robust TFR analysis. Two velocity definitions at 20 and 50 per cent of the peak flux were measured from the global H I profiles and adopted as proxies for the circular velocities. We compare our results with an identically constructed z= 0 TFR from the Ursa Major association (UMa) of galaxies. To ensure an unbiased comparison of the TFR, all the samples were treated identically regarding sample selection and applied corrections. We provide catalogues and an atlas showcasing the properties of the galaxies. Our analysis is focused on the zero points of the TFR and BTFR with their slopes fixed to the z = 0 relation. Our main results are: (1) The BUDH IES galaxies show more asymmetric H I profiles with shallower wings compared to the UMa galaxies, which is likely due to the environment in which they reside, (2) The luminosity-based z= 0.2 TFRs are brighter and bluer than the z = 0 TFRs, even when cluster galaxies are excluded from the BUDH IES sample, (3) The BTFR shows no evolution in its zero point over the past 2.5 billion yr and does not significantly change on the inclusion of cluster galaxies, and (4) proper sample selection and consistent corrections are crucial for an unbiased analysis of the evolution of the TFR

Deep sternal wound infection after open heart surgery: current treatment insights. A retrospective study of 36 cases

The aim of this study was to retrospectively evaluate the results of reconstructing infected post-sternotomy wounds, with either sternal plating and/or pectoralis major flap transposition or pedicled omentoplasty after previous vacuum-assisted closure (VAC) therapy. Between January 2005 and December 2010, 36 patients, suffering from deep sternal wound infection (DSWI) after coronary artery bypass grafting procedure, received (plastic) reconstructive surgery. All patients, treated in the Maastricht University Medical Centre (Departments of Plastic Surgery and Cardiothoracic Surgery), were selected for this study. For 22 patients, sternal refixation and reconstruction were obtained by sternal internal plate fixation combined with bilateral pectoralis major advancement flap. In 11 patients, a pedicled omentoplasty was performed, with or without split-skin graft and additional VAC therapy. Three patients only received a pectoralis plasty. We evaluated preoperative characteristics and post-operative course. Twenty-four patients (66.7%) had an uneventful post-operative course. Complications in the other patients included wound dehiscence, herniation of the donor site and infection of sternal plating material. Average sternal wound healing after sternal plating plus pectoralis plasty, pectoralis plasty and omentoplasty respectively accounted 7.7, 8.0 and 11.6 weeks. From our experience, we recommend VAC therapy plus delayed sternal plating and additional bilateral pectoralis major flap advancement as first repair option in case of DSWI. However, individual clinical conditions need to be taken into account when making a decision between the different available reconstructive options. Omentoplasty should be reserved for cases in which the sternum has recurrently fallen open after previous sternal plate refixation, or for cases in which the sternum defect is too extended

The Ursa Major association of galaxies - VI: a relative dearth of gas-rich dwarf galaxies

We determined the HI mass function of galaxies in the Ursa Major association of galaxies using a blind VLA-D array survey, consisting of 54 pointings in a cross pattern, covering the centre as well as the outskirts of the Ursa Major volume. The calculated HI mass function has best-fitting Schechter parameters {\theta}^* = 0.19+/-0.11 Mpc^{-3}, log(M^*_{HI}/M_{\odot}) = 9.8+/-0.8 and {\alpha} = -0.92+/-0.16. The high-mass end is determined by a complementary, targeted WSRT survey, the low-mass end is determined by the blind VLA survey. The slope is significantly shallower than the slopes of the HIPASS ({\alpha} = -1.37+/-0.03+/-0.05) and ALFALFA ({\alpha} = -1.33+/-0.02) HI mass functions, which are measured over much larger volumes and cover a wider range of cosmic environments: There is a relative lack of low HI mass galaxies in the Ursa Major region. This difference in the slope strongly hints at an environmental dependence of the HI mass function slope.Comment: 19 pages, 15 figures. Accepted for publication in MNRA

APERTIF, a focal plane array for the WSRT

In this paper we describe a focal plane array (FPA) prototype, based on Vivaldi elements, developed for the Westerbork Synthesis Radio Telescope (WSRT) to increase its instantaneous field of view by a factor 25 and double its current bandwidth. This prototype is the first step in a project that has the ambition to equip most of the WSRT antennas with FPAs to improve the survey speed of the telescope. Examples of scientific applications are surveys of the northern sky in polarised continuum and HI emission, and efficient searches for pulsars and transients.Comment: 7 pages, 6 figures. Presented at "The Evolution of Galaxies through the Neutral Hydrogen Window", Feb 1-3, 2008, Arecibo Observatory, Puerto Rico. High resolution versions of figures available in jpg-forma

A possible radio supernova in the outer part of NGC 3310

As part of an on-going radio supernova monitoring program, we have discovered a variable, compact steep spectrum radio source ~65 arcsec (~4 kpc) from the centre of the starburst galaxy NGC 3310. If the source is at the distance of NGC 3310, then its 5 GHz luminosity is ~3 x 10^{19} WHz^-1. The source luminosity, together with its variability characteristics, compact structure (<17 mas) and its association with a group of HII regions, leads us to propose that it is a previously uncatalogued type II radio supernova. A search of archival data also shows an associated X-ray source with a luminosity similar to known radio supernova.Comment: 5 pages, 3 figures. Accepted by MNRA

Star Formation Thresholds in Galactic Disks

We report the first results of a detailed study of the star formation law in a sample of 32 nearby spiral galaxies with well-measured rotation curves, HI and H$_2$ (as traced by CO) surface density profiles, and new \Ha CCD photometry. Our results strongly support the view that the formation of gravitationally bound interstellar clouds regulates the onset of widespread star formation -- at least in the outer regions of galactic disks.Comment: Will appear in July 1 ApJ. Abbreviated abstract. Postscript version available at http://www.astro.caltech.edu/~clm

BUDHIES IV:Deep 21-cm neutral Hydrogen, optical, and UV imaging data of Abell 963 and Abell 2192 at z ≃ 0.2

In this paper, we present data from the Blind Ultra-Deep H I Environmental Survey (BUDHIES), which is a blind 21-cm H I spectral line imaging survey undertaken with the Westerbork Synthesis Radio Telescope. Two volumes were surveyed, each with a single pointing and covering a redshift range of 0.164 < z < 0.224. Within these two volumes, this survey targeted the clusters Abell 963 and Abell 2192, which are dynamically different and offer unique environments to study the process of galaxy evolution within clusters. With an integration time of 117 × 12 h on Abell 963 and 72 × 12 h on Abell 2192, a total of 166 galaxies were detected and imaged in H I. While the clusters themselves occupy only 4 per cent of the 73 400 Mpc3 surveyed by BUDHIES, most of the volume consists of large-scale structures in which the clusters are embedded, including foreground and background overdensities and voids. We present the data processing and source detection techniques and counterpart identification based on a wide-field optical imaging survey using the Isaac Newton Telescope and deep ultraviolet (UV) Galaxy Evolution Explorer (GALEX) imaging. Finally, we present H I and optical catalogues of the detected sources as well as atlases of their global H I properties, which include integrated column density maps, position-velocity diagrams, global H I profiles, and optical and UV images of the H I sources

GMRT Detection of HI 21 cm-line Absorption from the Peculiar Galaxy in Abell 2125

Using the recently completed Giant Meterwave Radio Telescope, we have detected the HI 21 cm-line absorption from the peculiar galaxy C153 in the galaxy cluster Abell 2125. The HI absorption is at a redshift of 0.2533, with a peak optical depth of 0.36. The full width at half minimum of the absorption line is 100 km/s. The estimated column density of atomic Hydrogen is 0.7e22(Ts/100K) per sq. cm. The HI absorption is redshifted by ~ 400 km/s compared to the [OIII] emission line from this system. We attribute this to an in-falling cold gas, or to an out-flowing ionised gas, or to a combination of both as a consequence of tidal interactions of C153 with either a cluster galaxy or the cluster potential.Comment: 9 pages, 2 figures, uses jaa.sty (included