Accumulation of F-18 FDG in the infected pulmonary cyst in a patient with hydatid disease

Echinococcosis is endemic in certain parts of the world, including Turkey. When the pulmonary cyst has characteristic features, it can be easily diagnosed, but when the appearance changes as a result of complications, the cyst may resemble a malignant lesion. We presented a complicated pulmonary hydatid disease patient who was referred to our department for PET-CT, after the detection of 2 lung lesions

Imaging of Chemokine Receptor CXCR4 in Mycosis Fungoides Using 68Ga-Pentixafor PET/CT

A 52-year-old woman diagnosed with mycosis fungoides was referred for F-18-FDG PET/CT before treatment for the evaluation of disease severity. The patient also underwent Ga-68-pentixafor PET/CT for further evaluation. FDG uptake was observed in cervical, axillary, and pelvic lymph nodes and multiple widespread skin lesions throughout the body, suggestive of extensive involvement of mycosis fungoides. All lesions were visually identifiable with high target-to-background ratio on Ga-68-pentixafor PET/CT which demonstrated marked CXCR4 expression in all lesions that were detected using F-18-FDG PET/CT

THE ROLE OF 18F-FDG PET-CT IN DIAGNOSIS AND PREDICTION OF PROGNOSIS IN MALIGNANT PLEURAL MESOTHELIOMA

Objective: The purpose of this study is to evaluate the performance of 18F-FDG PET/CT in the differential diagnosis of malignant and benign pleural disease as well as its prognostic value in the malignant pleural mesothelioma (MPM)

Favorable Survival Time Provided with Radioembolization in Hepatocellular Carcinoma Patients with and Without Portal Vein Thrombosis

WOS: 000352954500005PubMed ID: 25760644Purpose: Although some algorithms are defined for the treatment of advanced hepatocellular carcinoma (HCC), the expected survival cannot be prolonged as it is intended. Treatment options for this group of patients are limited. Radioembolization with yttrium-90 (Y-90) microspheres is a new treatment modality, which has also been used in advanced HCC patients. In this study, the authors aimed to assess the efficiency of radioembolization with Y-90 microspheres and evaluate prognostic factors that influence the survival in HCC patients. Patients and Methods: The authors retrospectively evaluated data of 29 HCC patients who had radioembolization with Y-90 resin or glass microspheres between May 2009 and January 2014. Patient survival was evaluated by using the Kaplan-Meier method. Subgroup comparisons in terms of age, sex, prior treatment status before radioembolization, tumor burden, time between HCC diagnosis and radioembolization, alpha fetoprotein (AFP) level before radioembolization, presence of portal vein thrombosis (PVT), hepatopulmonary shunt ratio, extrahepatic disease burden, multifocality, bilaterality, Eastern Cooperative Oncology Group (ECOG), Child-Pugh, and Barcelona Clinic Liver Cancer (BCLC) status were performed to evaluate prognostic factors that affected survival. Results: There were 29 HCC patients (mean age: 59.9 +/- 12 years) in the patient group. Grade <= 1 and 2 ECOG performance status was present in 19 and 10 patients, respectively. Twenty-six patients were classified as Child A and 3 patients as Child B. According to the BCLC staging system, 18 patients were in stage B and 11 patients were in stage C. PVT was diagnosed in 12 patients. The median follow-up was 15 months. The median overall survival was 17 +/- 2.5 months. BCLC disease stage was a significant prognostic variable associated with survival, but other parameters, even the presence of PVT, were found to be not significantly affecting survival. Conclusion: Radioembolization provides favorable survival time in advanced HCC patients. Even patients who are not eligible for transarterial chemoembolization due to PVT can have radioembolization without a decrease in the median survival time

Role of red blood cell scintigraphy for determining the localization of gastrointestinal bleeding

BACKGROUN

Hepatic Adenomatosis May Mimic Metastatic Lesions of Liver With F-18-FDG PET/CT

Hepatic adenomatosis is an uncommon benign neoplasm, with the presence of multiple adenomas (generally more than 4) within the liver. A 52-yearold woman presented with multiple (>10) solid liver lesions detected with abdominal ultrasonography and verified with magnetic resonance imaging (MRI). Subsequently, F-18 FDG PET/CT demonstrated increased uptake in these lesions. Histology revealed hepatic adenomatosis. F-18 FDG PET/CT cannot reliably differentiate hepatic adenomas from malignant processes on the basis of uptake

Role of red blood cell scintigraphy for determining the localization of gastrointestinal bleeding

BACKGROUN

Comparison of 2D planar and 3D volumetric methods for estimation of split renal function by ^99mTc-DMSA scintigraphy.

© 2022 Associazione Italiana di Fisica Medica e SanitariaPurpose: Split renal function (SRF) can be measured by using several methods in 99mTc-DMSA scintigraphy. Geometric mean (GM) based methods derived from planar images(2D) have been used for several years, besides; 3D-methods were also reported as an option for assessment of SRF. The purpose of this study to compare 2D and 3D methods for calculation of SRF in pediatric and adult patients. Methods: We evaluated 212 patients, underwent both planar and SPECT 99mTc-DMSA scintigraphy.2D-SRFs were calculated by GM without background correction (SRFnobcg), GM with background correction in crescent formation from lower lateral borders (SRFcres), and GM with background correction in circumferential formation, including the whole kidney surroundings (SRFcirc). In 3D settings, SRF was measured with SPECT (SRFspect). Paired t-test was used to compare the mean SRFs of each group. Bland-Altman method was used as an agreement method for each method. Analyses were performed based on left kidney SRFs. Results: In comparison of 2D and 3D methods, SRFspect was significantly different from SRFnobcg and SRFcres (p=<0.001) but not from SRFcirc (p = 0.155) in all patients. Similar results were found for patients with high creatinine level, SRFcirc and SRFspect were not significantly different (p = 0.317), while significant differences were found between SRFspect and SRFnobcg/SRFcres (p=<0.001).On the other hand, all 2D-methods showed statistical differences (p=<0.001–0.026) from 3D-method in pediatric patients. Bland-Altman-plot demonstrated that SRFcirc underestimated the poor functioning kidneys. Conclusion: SRFcirc can be used in measurement of SRF in adult patients with normal functioning kidneys in busy clinics. However, SRFspect provides more accurate results and suggested particularly for pediatric patients and poor functioning kidneys