The Fermi Gamma-ray Burst Monitor: Results from the first two years

In the first two years since the launch of the Fermi Observatory, the Gamma-ray Burst Monitor (GBM) has detected over 500 Gamma-Ray Bursts (GRBs), of which 18 were confidently detected by the Large Area Telescope (LAT) above 100 MeV. Besides GRBs, GBM has triggered on other transient sources, such as Soft Gamma Repeaters (SGRs), Terrestrial Gamma-ray Flashes (TGFs) and solar flares. Here we present the science highlights of the GBM observations.Comment: 4 pages, 1 figure, Proceedings of the 8th Workshop on Science with the New Generation of High Energy Gamma-ray Experiments (SciNeGHE 2010), Nuovo Cimento C, in pres

A Profile of Third-Grade Proficiency in Erie County

Produced by the United Way of Buffalo and Erie County, this report details information about why it is important for third graders in Erie County to be proficient in reading and math. Children below grade-level proficiency in third grade are much less likely to graduate from high school.Without mastering early reading and math skills, a child will fall further and further behind their peers. Without a high school degree, our children will face a future in which they are less likely to be able to support themselves through employment, and are more likely to live in poverty

Project Retrosight. Understanding the returns from cardiovascular and stroke research: Policy Report

Copyright @ 2011 RAND Europe. All rights reserved. The full text article and the summary of the article are both available via the links below.This project explores the impacts arising from cardiovascular and stroke research funded 15-20 years ago and attempts to draw out aspects of the research, researcher or environment that are associated with high or low impact. The project is a case study-based review of 29 cardiovascular and stroke research grants, funded in Australia, Canada and UK between 1989 and 1993. The case studies focused on the individual grants but considered the development of the investigators and ideas involved in the research projects from initiation to the present day. Grants were selected through a stratified random selection approach that aimed to include both high- and low-impact grants. The key messages are as follows: 1) The cases reveal that a large and diverse range of impacts arose from the 29 grants studied. 2) There are variations between the impacts derived from basic biomedical and clinical research. 3) There is no correlation between knowledge production and wider impacts 4) The majority of economic impacts identified come from a minority of projects. 5) We identified factors that appear to be associated with high and low impact. This report presents the key observations of the study and an overview of the methods involved. It has been written for funders of biomedical and health research and health services, health researchers, and policy makers in those fields. It will also be of interest to those involved in research and impact evaluation.This study was initiated with internal funding from RAND Europe and HERG, with continuing funding from the UK National Institute for Health Research, the Canadian Institutes of Health Research, the Heart and Stroke Foundation of Canada and the National Heart Foundation of Australia. The UK Stroke Association and the British Heart Foundation provided support in kind through access to their archives

New walking and cycling infrastructure and modal shift in the UK: A quasi-experimental panel study

Heavy dependency on car use leads to traffic congestion, pollution, and physical inactivity, which impose high direct and indirect costs on society. Promoting walking and cycling has been recognised as one of the means of mitigating such negative effects. Various approaches have been taken to enhance walking and cycling levels and to reduce the use of automobiles. This paper examines the effectiveness of infrastructure interventions in promoting walking and cycling for transport. Two related sets of panel data, covering elapsed time periods of one and two years, were analysed to track changes in travel behaviour following provision of new walking and cycling infrastructure so that modal shift from private car use to walking and cycling can be investigated. Two types of exposure measures were tested: distance from the infrastructure (a measure of potential usage), and actual usage of the infrastructure. Only the latter measure was statistically significantly associated with modal shift. This in turn suggested that infrastructure provision was not a sufficient condition for modal shift, but may have been a necessary condition. Along with the use of new infrastructure, the loss of employment, higher education, being male and being part of the ethnic majority were consistently found to be significantly and positively associated with modal shift towards walking and cycling. The findings of this study support the construction of walking and cycling routes, but also suggest that such infrastructure alone may not be enough to promote active travel.This paper was written on behalf of the iConnect consortium (www.iconnect.ac.uk; Christian Brand, Fiona Bull, Ashley Cooper, Andy Day, Nanette Mutrie, David Ogilvie, Jane Powell, John Preston and Harry Rutter). The iConnect consortium was funded by the Engineering and Physical Sciences Research Council (Grant reference EP/G00059X/1) and David Ogilvie is also supported by the Medical Research Council [Unit Programme number MC_UP_12015/6] and the Centre for Diet and Activity Research (CEDAR), a UKCRC Public Health Research Centre of Excellence. We thank the survey participants for their time and the consortium manager Karen Ghali for managing data collection

The FEeding Support Team (FEST) randomised, controlled feasibility trial of proactive and reactive telephone support for breastfeeding women living in disadvantaged areas

Peer reviewedPublisher PD

Constraining the Dark Matter decay lifetime with very deep observations of the Perseus cluster with the MAGIC telescopes

We present preliminary results on Dark Matter searches from observations of the Perseus galaxy cluster with the MAGIC Telescopes. MAGIC is a system of two Imaging Atmospheric Cherenkov Telescopes located in the Canary island of La Palma, Spain. Galaxy clusters are the largest known gravitationally bound structures in the Universe, with masses of ~10^15 Solar masses. There is strong evidence that galaxy clusters are Dark Matter dominated objects, and therefore promising targets for Dark Matter searches, particularly for decay signals. MAGIC has taken almost 300 hours of data on the Perseus Cluster between 2009 and 2015, the deepest observational campaign on any galaxy cluster performed so far in the very high energy range of the electromagnetic spectrum. We analyze here a small sample of this data and search for signs of dark matter in the mass range between 100 GeV and 20 TeV. We apply a likelihood analysis optimized for the spectral and morphological features expected in the dark matter decay signals. This is the first time that a dedicated Dark Matter optimization is applied in a MAGIC analysis, taking into account the inferred Dark Matter distribution of the source. The results with the full dataset analysis will be published soon by the MAGIC Collaboration

Determining Ratios of WIMP-Nucleon Cross Sections from Direct Dark Matter Detection Data

Weakly Interacting Massive Particles (WIMPs) are one of the leading candidates for Dark Matter. So far the usual procedure for constraining the WIMP-nucleon cross sections in direct Dark Matter detection experiments have been to fit the predicted event rate based on some model(s) of the Galactic halo and of WIMPs to experimental data. One has to assume whether the spin-independent (SI) or the spin-dependent (SD) WIMP-nucleus interaction dominates, and results of such data analyses are also expressed as functions of the as yet unknown WIMP mass. In this article, I introduce methods for extracting information on the WIMP-nucleon cross sections by considering a general combination of the SI and SD interactions. Neither prior knowledge about the local density and the velocity distribution of halo WIMPs nor about their mass is needed. Assuming that an exponential-like shape of the recoil spectrum is confirmed from experimental data, the required information are only the measured recoil energies (in low energy ranges) and the number of events in the first energy bin from two or more experiments.Comment: 33 pages, 20 eps figures; v2: typos fixed, references added and updated, revised version for publicatio

Process evaluation for the FEeding Support Team (FEST) randomised controlled feasibility trial of proactive and reactive telephone support for breastfeeding women living in disadvantaged areas

PMID: 22535794 [PubMed] PMCID: PMC3341595 Free PMC ArticlePeer reviewe

Community-based post-stroke service provision and challenges: a national survey of managers and inter-disciplinary healthcare staff in Ireland.

ABSTRACT: BACKGROUND: The extent of stroke-related disability typically becomes most apparent after patient discharge to the community. Maximising rehabilitation input at this point can minimise the impact of disability. As part of the Irish National Audit of Stroke Care (INASC), a national survey of community-based allied health professionals and public health nurses was conducted. The aim was to document the challenges to service availability for patients with stroke in the community and to identify priorities for service improvement. METHODS: The study was a cross-sectional tailored interview survey with key managerial and service delivery staff. As comprehensive listings of community-based health professionals involved in stroke care were not available, a cascade approach to information gathering was adopted. Representative regional managers for services incorporating stroke care (N=7) and disciplinary allied health professional and public health nurse managers (N=25) were interviewed (94% response rate). RESULTS: Results indicated a lack of formal, structured community-based services for stroke, with no designated clinical posts for stroke care across disciplines nationally. There was significant regional variation in availability of allied health professionals. Considerable inequity was identified in patient access to stroke services, with greater access, where available, for older patients (\u3e65 years). The absence of a stroke strategy and stroke prevalence statistics were identified as significant impediments to service planning, alongside organisational barriers limiting the recruitment of additional allied health professional staff, and lack of sharing of discipline-specific information on patients. CONCLUSIONS: This study highlighted major gaps in the provision of inter-disciplinary team community-based services for people with stroke in one country. Where services existed, they were generic in nature, rarely inter-disciplinary in function and deficient in input from salient disciplines. Challenges to optimal care included the need for strategic planning; increased funding of healthcare staff; increased team resources and teamwork; and removal of service provision barriers based on age. There were notably many challenges beyond funding. Similar evaluations in other healthcare systems would serve to provide comparative lessons to serve to tackle this underserved aspect of care for patients with stroke and their families