Pheochromocytoma multisystem crisis treated with emergency surgery: a case report and literature review

Background: Pheochromocytoma is a neuroendocrine tumor that predominantly presents with hypertension, palpitations, and tachycardia due to excessive catecholamine excretion. Although pheochromocytoma multisystem crisis (PMC) is relatively rare, urologists and clinicians should focus on early diagnosis as delay in initiating the appropriate treatment can lead to mortality Case presentation: A 70-year-old man developed ileus after a few days of medication for hypertension. Computed tomography incidentally revealed a left adrenal mass. This finding together with his clinical course was compatible with pheochromocytoma. An α-blocker was administered immediately, and his blood pressure was well controlled. However, his general condition and laboratory data deteriorated rapidly, and the patient was diagnosed with PMC with lethal status. Thus, emergency adrenalectomy was performed without confirmation of catecholamine levels. From the resected specimen, his tumor was judged as pheochromocytoma. On immunohistochemical analysis, the proliferation index evaluated by Ki-67 staining was 9.7 %. This case report was approved by the Human Ethics Review Committee of the Nagasaki University Hospital. Conclusion: The present case of PMC was successfully treated with emergency surgery. The benign pheochromocytoma also presented with high cell proliferation potential, which may be a cause of the extreme aggressiveness of PMC

La substitution des images aux reliques, et ses limites, dans la diffusion de la virtus des saints (Espace FranÇais, fin XIIIe-XVe S.)

After an earlier study regarding the Italian corpus, this article continues for the French territory an ample research started from the pioneering views of André Vauchez regarding the substitution of images for relics in the employment of the virtus of saints away from their tomb. - The article does not deal with images of the Virgin. - On the chronological level, the French corpus fits these views much better than the Italian, since the phenomenon is only really observed there from the 14th cent. In addition, a series of new data confirm that various images became “focal points” of the cult of saints far away from their tomb. But, as for the Italian corpus, in the texts studied it is more often contact relics and tiny first-class relics that appear as efficacious carriers of virtus. The last pages of the article underline how much the presentation, in spite of everything, only gives a very partial picture of a particularly complex reality.SCOPUS: re.jinfo:eu-repo/semantics/publishe