The Influence of short-term land use change on soil evolution in the centre-south coastal areas of Sardinia

The land use change in short-term (time and space) in the Mediterranean context can be induced by phenomena like destruction of the autochthonous plant species, land abandonment, overgrazing, fire, urbanization (above all for touristic purpose), etc. These phenomena can lead to soil’s degradation conditions causing a loss of physical and biological productivity and the consequent emphasis in desertification processes. Desertification is considered one of the biggest environmental problems in Mediterranean areas (ICCD, 1994), and Sardinia is one of the most affected regions in Europe (UNEP, 1992; Imeson and Emmer, 1992). In Sardinia changes happened during the last decades (such as industrialization, coastal urban areas expansion, etc.) have often resulted in repercussions on the environmental ecosystems and foremost on soils. An important decrease of fertile lands and a consequent increase of marginal and unproductive areas have been observed; this fact has taken to manifest environmental and economic repercussions. In Sardinia such degradation phenomena are particularly evident in coastal areas, where the uncontrolled urbanization and the natural touristic vocation represent relevant impact types. In fact, in 1897 km of coastal lands (500 km are represented by dunal systems) 40% is subjected to deep erosion phenomena, that often are caused by wrong management actions. For these reasons the knowledge of their nature and expansion is of primary importance to carry out correct choices in land use. This work shows an example of a comparative investigation on coastal ecosystems particularly under human pressure. The investigated areas are located along the Centre–North coast of Sardinia. Particularly they concern: a) soils on limestone formations, forestry live oak cover and pasture land use (goat and swine); b) soils on fixed dunes, reforestation with pine and touristic-recreational land use foremost. In the areas several soil profiles have been realized to investigate the influence of the land use change, occurring in short-term in both places, on the evolution and degradation processes of soils

Cherenkov telescope array extragalactic survey discovery potential and the impact of axion-like particles and secondary gamma rays

The Cherenkov Telescope Array (CTA) is about to enter construction phase and one of its main key science projects is to perform an unbiased survey in search of extragalactic sources. We make use of both the latest blazar gamma--ray luminosity function and spectral energy distribution to derive the expected number of detectable sources for both the planned Northern and Southern arrays of the CTA observatory. We find that a shallow, wide survey of about 0.5 hour per field of view would lead to the highest number of blazar detections. Furthermore, we investigate the effect of axion-like particles and secondary gamma rays from propagating cosmic rays on the source count distribution, since these processes predict different spectral shape from standard extragalactic background light attenuation. We can generally expect more distant objects in the secondary gamma-ray scenario, while axion-like particles do not significantly alter the expected distribution. Yet, we find that, these results strongly depend on the assumed magnetic field strength during the propagation. We also provide source count predictions for the High Altitude Water Cherenkov observatory (HAWC), the Large High Altitude Air Shower Observatory (LHAASO) and a novel proposal of a hybrid detector.Comment: 16 pages, 4 figures, ApJ 2017 in pres

Clinic manifestations in granulomatosis with polyangiitis

Granulomatosis with polyangiitis (GPA), formerly Wegener's granulomatosis (WG), is an uncommon immunologically mediated systemic small-vessel vasculitis that is pathologically characterised by an inflammatory reaction pattern (necrosis, granulomatous inflammation and vasculitis) that occurs in the upper and lower respiratory tracts and kidneys. Although the aetiology of GPA remains largely unknown, it is believed to be autoimmune in origin and triggered by environmental events on a background of genetic susceptibility.In Europe, the prevalence of GPA is five cases per 100,000 population, with greater incidence in Northern Europe. GPA can occur in all racial groups but predominantly affects Caucasians. Both sexes are affected equally. GPA affects a wide age range (age range, 8-99 years).Granulomatosis with polyangiitis is characterised by necrotising granulomatous lesions of the respiratory tract, vasculitis and glomerulonephritis. Classically, the acronym ELK is used to describe the clinical involvement of the ear, nose and throat (ENT); lungs; and kidneys. Because the upper respiratory tract is involved in 70-100% of cases of GPA, classic otorhinolaryngologic symptoms may be the first clinical manifestation of disease. The nasal cavity and the paranasal sinuses are the most common sites of involvement in the head and neck area (85-100%), whereas otological disease is found in approximately 35% (range, 19-61%) of cases.Diagnosis of GPA is achieved through clinical assessment, serological tests for anti-neutrophil cytoplasmic antibodies (ANCA) and histological analysis. The 10-year survival rate is estimated to be 40% when the kidneys are involved and 60-70% when there is no kidney involvement.The standard therapy for GPA is a combination of glucocorticoids and cyclophosphamide. In young patients, cyclophosphamide should be switched to azathioprine in the maintenance phase.A multidisciplinary approach, involving otorhinolaryngologists, oral and maxillofacial surgeons, oral physicians, rheumatologists, renal and respiratory physicians, and ophthalmologists, is necessary for the diagnosis and therapeutic treatment of GPA. ENT physicians have a determining role in recognising the early onset of the disease and starting an appropriate therapy

Case study on economic return on investments for safety and emergency lighting in road tunnels

While planning a double-hole road tunnel with a length higher than one km, it is important to pay attention to the safety factor if an accident occurs. If there is a power outage, in order to avoid critical situations that could jeopardize the safety of the people present (facilitating the stream coming out from the tunnel and the arrival of the emergency personnel), it is really important to guarantee uninterrupted lighting of roadways, mandatory emergency lay-bys, and ways of escape. Uninterrupted service of the lighting systems supply must be guaranteed, in accordance with the current regulations, through the exertion of UPS (Uninterruptible Power Supply) and power units. During tunnel construction, such devices represent a cost that must be amortized. In this case study, which takes into consideration a section of a road tunnel characterized by emergency lay-bys and ways of escape, emergency and security lighting were planned and installation and management costs were evaluated. The goal of this research was the creation of a cash flow thanks to the energy generated by photovoltaic panels, in a way that the service life of the system (25 years) coincided with the amortization of the costs of the backup electrical equipment installation (complying with the regulations). The possibility of over-dimensioning the UPS and providing it with a proper photovoltaic panel surface (235 kWp) to generate and exchange electric energy with the grid was taken into consideration

Nanoparticles modified screen printed electrode for electrochemical determination of COD

The Chemical Oxygen Demand (COD) is a parameter widely used to determine organic pollutants in water and is defined as the number of oxygen equivalents necessary to oxidize the organic compounds. The standard method for COD measurement (the dichromate titration) suffers from several inherent drawbacks such as the long time of the process and the consumption of toxic chemicals. Hence, interest is growing towards those methods employing electrochemical oxidation of organic compounds, as they allow to dispense with toxic reagents and above all to perform a continuous determination. In this work a new electrochemical method for COD measurement has been developed based on direct oxidation of organic molecules on suitably modified electrodic surfaces. In particular, we have developed various sensors based on modified working electrode surfaces obtained by electrodepositing copper and/or nickel oxide nanoparticles onto several commercial screen printed electrodes. Glucose was used as the standard compound for COD measurements: C6H12O6 + 6O2 → 6CO2 + 6H2O The metallic nanoparticles catalyze the oxidation of the glucose, as well as of different organic pollutants, and make the detection possible at relatively low potential, also in presence of chloride as interferent. The analytical parameters were optimized and the results obtained highlight how the electrodeposition of different metallic nanoparticles onto several screen printed electrode surfaces can influence the selectivity and sensitivity towards the COD detection in real matrices, via electrochemical method. The results were compared with those obtained by the standard method and showed a good agreement. These findings provide an interesting strategy to obtain a simple, cheap, portable and eventually continuous sensor for COD measurement

A methodological comparison between energy and environmental performance evaluation

The European Union is working on strategies in order to increase the energy efficiency of buildings. A useful solution is to identify the energy performance of buildings through the Energy Performance Certificate (EPC), as it provides information for the comparison of buildings with different architectural typology, shape, design technology and geographic location. However, this tool does not assess the real energy consumption of the building and does not always take into account its impact on the environment. In this work, two different types of analysis were carried out: one based only on the energy efficiency and the other one based on the environmental impact. Those analyses were applied on a standard building, set in three different Italian locations, with the purpose of obtaining cross-related information. After the evaluation of the results, interventions on some parameters (walls insulation, windows frame, filler gas in the insulated glazing) have been identified in order to improve the energy behavior of the building with an acceptable environmental impact. The aim of this paper is to propose a methodology that integrates the EPC with green building rating systems, leading to a more conscious choice of retrofit interventions as a compromise between energy performances and environmental impact

A Method to Evaluate the Stimulation of a Real World Field of View by Means of a Spectroradiometric Analysis

Stimulation elicited by a real world field of view is related to the color, the intensity and the direction of the information reaching the eye: different spectral power distributions of light trigger different responses. An evaluation of the stimulation provided by the field of view can be performed by measuring the spectral radiance with a spectroradiometer and weighting this data with an efficiency curve. Different weights (physical, physiological and psychological) can lead to different analyses and consequently to different results. The proposed method allows an overall and simplified evaluation of the field of view based on spectral and luminance measures and a script that processes the luminous information. The final aim of this approach is to provide further information about the light stimulation reaching the retina and to supply a qualitative evaluation of the field of view, allowing to know how much stimulation is coming from a certain area within the visual field depending on the type of surface, basing on spectral and directional information. This approach can have practical implications, allowing technicians and designers to take into consideration the possible visual fields, in order to properly shape the features of stimulation throughout the day, hence following a field of view-based dynamic design

A Method to Evaluate the Stimulation of a Real World Field of View by Means of a Spectroradiometric Analysis

Stimulation elicited by a real world field of view is related to the color, the intensity and the direction of the information reaching the eye: different spectral power distributions of light trigger different responses. An evaluation of the stimulation provided by the field of view can be performed by measuring the spectral radiance with a spectroradiometer and weighting this data with an efficiency curve. Different weights (physical, physiological and psychological) can lead to different analyses and consequently to different results. The proposed method allows an overall and simplified evaluation of the field of view based on spectral and luminance measures and a script that processes the luminous information. The final aim of this approach is to provide further information about the light stimulation reaching the retina and to supply a qualitative evaluation of the field of view, allowing to know how much stimulation is coming from a certain area within the visual field depending on the type of surface, basing on spectral and directional information. This approach can have practical implications, allowing technicians and designers to take into consideration the possible visual fields, in order to properly shape the features of stimulation throughout the day, hence following a field of view-based dynamic design

Urban lighting project for a small town: comparing citizens and authority benefits

The smart and resilient city evolves by slow procedures of mutation without radical changes, increasing the livability of its territory. The value of the city center in a Smart City can increase through urban lighting systems: its elements on the territory can collect and convey data to increase services to city users; the electrical system becomes the so-called Smart Grid. This paper presents a study of smart lighting for a small town, a touristic location inside a nature reserve on the Italian coast. Three different approaches have been proposed, from minimal to more invasive interventions, and their effect on the territory has been investigated. Based on street typology and its surroundings, the work analyzes the opportunity to introduce smart and useful services for the citizens starting from a retrofitting intervention. Smart city capabilities are examined, showing how it is possible to provide new services to the cities through ICT (Information and Communication Technology) without deep changes and simplifying the control of basic city functions. The results evidence an important impact on annual energy costs, suggesting smart grid planning not only for metropolis applications, but also in smaller towns, such as the examined one

Numb Isoforms Deregulation in Medulloblastoma and Role of p66 Isoform in Cancer and Neural Stem Cells

Numb is an intracellular protein with multiple functions. The two prevalent isoforms, Numb p66 and Numb p72, are regulators of differentiation and proliferation in neuronal development. Additionally, Numb functions as cell fate determinant of stem cells and cancer stem cells and its abnormal expression has been described in several types of cancer. Involvement of deregulated Numb expression has been described in the malignant childhood brain tumor medulloblastoma, while Numb isoforms in these tumors and in cancer stem-like cells derived from them, have not been studied to date. Here we show that medulloblastoma stem-like cells and cerebellar neuronal stem cells (NSCs) express Numb p66 where its expression tampers stemness features. Furthermore, medulloblastoma samples evaluated in this study express decreased levels of Numb p66 while overexpressed Numb p72 compared with normal tissues. Our results uncover different roles for the two major Numb isoforms examined in medulloblastoma and a critical role for Numb p66 in regulating stem-like cells and NSCs maintenance