Strategic evaluation study on child-centred community development - Synthesis report

This strategic formative evaluation was carried out by Wageningen International Capacity Development & Institutional Change (CD&IC) programme from May to September 2009. The evaluation aims to obtain insight into the understanding of CCCD within Plan, and to learn more about the factors that favour or obstruct the implementation of Child Centred Community Development (CCCD) in practice. Suggestions on improving CCCD as an approach to development are provided, as well as an analysis of capacity development needs for CCCD implementation. This evaluation report is a product of Phase I of the complete anticipated evaluation trajectory. Phase II will most likely include an international workshop around the findings of Phase I. The findings of Phase I will contribute to the track record for the MFS II application to the Dutch Ministry of Foreign Affairs which Plan Netherlands is currently preparing. The study comprised a desk research stage, which reviewed relevant Plan documentation as well as consultations with key stakeholders within Plan worldwide. During this stage face to face interviews were conducted in Plan IH office in Woking, and at NLNO in Amsterdam. Other interviews with stakeholders in ROs and NOs were done using Skype. Furthermore two field studies were conducted in Kenya and Bangladesh. Given the fact that the topic of the study is broad, it is limited to analysis of the wider issues pertaining to CCCD rather than in-depth detailed analysis of these issues

A novel platform for the production of nonhydroxylated gelatins based on the methylotrophic yeast Hansenula polymorpha

The use of yeast as a host for heterologous expression of proteins that are normally derived from animal tissue is a promising way to ensure defined products that are devoid of potential harmful animal side products. Here we report on the production and secretion of a custom-designed gelatin, Hu3–His8, by the yeast Hansenula polymorpha. We observed that Hu3–His8 was poorly secreted by the heterologous Saccharomyces cerevisiae invertase secretion signal. In contrast, the S. cerevisiae mating factor α prepro sequence efficiently directed secretion into the culture medium. However, at higher copy numbers, intracellular accumulation of Hu3–His8 precursors occurred. Overproduction of Erv29p, a protein required for packaging of the glycosylated pro-α factor into COPII vesicles, did not improve gelatin secretion in the multicopy strain. Previously, H. polymorpha was reported to hydroxylate proline residues in gelatinous sequences. In contrast, we were unable to detect hydroxyprolines in the secreted Hu3–His8. Also, we failed to identify a gene encoding prolyl-4-hydroxylase in the H. polymorpha genome.

A high‐throughput Raman notch filter set

A chevron‐type Raman notch filter (RNF) set is described. lt combines a high signal throughput (up to 90% around 1600 cm−1 and ≳80% between and 700 and 2700 cm−1) with a laser line suppression of 108–109. The filter set can be used to replace the first two dispersion stages in triple‐stage Raman monochromators commonly employed in multichannel detection systems. This yields a gain in intensity of the detected Raman signal of a factor of 4. It is shown that in Raman spectrometers with a backscatter geometry, the filter set can also be used to optically couple the microscope and the spectrometer. This leads to a further increase in signal intensity of a factor of 3–4 as compared to the situation where a beam splitter is used. Additional advantages of the RNF set are the fact that signal throughput is almost polarization independent over a large spectral interval and that it offers the possibility to simultaneously record Stokes and anti‐Stokes spectra

Compositional dependence of the giant magnoresistance in FexRh1-x thin films

In this article we report on the magnetic and transport properties of FexRh1-x thin films, prepared by evaporation in high vacuum, in the composition range 0.4

Mechanisms controlling the intra-annual mesoscale variability of SST and SPM in the southern North Sea

Thermal and optical remote sensing data were used to investigate the spatial and temporal distribution of sea surface temperature (SST) and of suspended particulate matter (SPM) in the southern North Sea. Monthly SST composites showed pronounced seasonal warming of the southern North Sea and delineated the English coastal and continental coastal waters. The East-Anglia Plume is the dominant feature of the English coastal waters in the winter and autumn SPM composites, and the Rhine region of freshwater influence (ROFI), including the Flemish Banks, is the dominant feature of the continental waters. These mesoscale spatial structures are also influenced by the evolution of fronts, such as the seasonal front separating well-mixed water in the southern Bight, from the seasonally stratified central North Sea waters. A harmonic analysis of the SST and SPM images showed pronounced seasonal variability, as well as spring-neap variations in the level of tidal mixing in the East Anglia Plume, the Rhine ROFI and central North Sea. The harmonic analysis indicates the important role played by the local meteorology and tides in governing the SST and near-surface SPM concentrations in the southern North Sea. In the summer, thermal stratification affects the visibility of SPM to satellite sensors in the waters to the north of the Flamborough and Frisian Fronts. Haline stratification plays an important role in the visibility of SPM in the Rhine ROFI throughout the year. When stratified, both regions typically exhibit low surface SPM values. A numerical model study, together with the harmonic analysis, highlights the importance of tides and waves in controlling the stratification in the southern North Sea and hence the visibility of SPM. © 2011 Elsevier Ltd

Climate adaptive building shells for the future – optimization with an inverse modelling approach

Most of currently designed and constructed building shells are fairly static systems which limits the possibilities for optimal energy performance and/or optimal indoor comfort. Solar shading is often only regulated by hand with (indoor) lamellas. This static behaviour of the shell often leads to discomfort and a high energy use for the various installations which are needed to climatise the building. In common design practice energy performance calculation programs or, in the best case, dynamic building simulation programs are used as a tool to improve the building shell performance. Different options for façade constructions are compared to retrieve the best result in energy use. In the ongoing FACET project (Dutch acronym: ‘Adaptive future façade technology for increased comfort and low energy use’) a completely new, inverse modelling approach is chosen by asking the question: "What would be the ideal, dynamic properties of a building shell to get the desired indoor climate at variable outdoor climate conditions?" By reversing the design approach, a set of ideal, but realistic building shell parameters is computed for different climate conditions, at various time scales (seasons, day-night, instantaneous). The ‘ideal’ adaptive behaviour makes it possible to maximize comfort and to minimize energy demand. Technologies to reach this ‘ideal’ behaviour are partly already available, in low or high tech solutions, such as smart glazing, variable vacuum insulation, insulating window covering, etc. However, further technology development is desired to fully meet the requirements. This paper describes results of the inverse thermal modelling for a climate adaptive building shell. It shows that ideally adaptive building shells have the potential to practically eliminate the heat demand and to reduce the total heating and cooling demand by a factor 10, compared to state of the art new built offices under the Dutch climate. This is even a factor 2–3 lower compared to the very energy efficient passive house technology. The extremely low energy demand facilitates new technologies like compact heat/cold storages and the practical realisation of zero energy, or energy producing buildings in the near future

Micromachining of buried micro channels in silicon

A new method for the fabrication of micro structures for fluidic applications, such as channels, cavities, and connector holes in the bulk of silicon wafers, called buried channel technology (BCT), is presented in this paper. The micro structures are constructed by trench etching, coating of the sidewalls of the trench, removal of the coating at the bottom of the trench, and etching into the bulk of the silicon substrate. The structures can be sealed by deposition of a suitable layer that closes the trench. BCT is a process that can be used to fabricate complete micro channels in a single wafer with only one lithographic mask and processing on one side of the wafer, without the need for assembly and bonding. The process leaves a substrate surface with little topography, which easily allows further processing, such as the integration of electronic circuits or solid-state sensors. The essential features of the technology, as well as design rules and feasible process schemes, will be demonstrated on examples from the field of ¿-fluidic