271 research outputs found
Study on the One-Proton Halo Structure in Al
The Glauber theory has been used to investigate the reaction cross section of
proton-rich nucleus Al. A core plus a proton structure is assumed for
Al. HO-type density distribution is used for the core while the density
distribution for the valence proton is calculated by solving the eigenvalue
problem of Woods-Saxon potential. The transparency function in an analytical
expression is obtained adopting multi-Gaussian expansion for the density
distribution. Coulomb correction and finite-range interaction are introduced.
This modified Glauber model is apt for halo nuclei. A dominate s-wave is
suggested for the last proton in Al from our analysis which is possible
in the RMF calculation.Comment: 4 pages, 4 figure
Comparison of praziquantel pharmacokinetics and tissue distribution in fresh and brackish water cultured grass carp (ctenopharyngodon idellus) after oral administration of single bolus
Study of and
The decays and have been
investigated with a sample of 225.2 million events collected with the
BESIII detector at the BEPCII collider. The branching fractions are
determined to be and . Distributions of the angle
between the proton or anti-neutron and the beam direction are well
described by the form , and we find
for and
for . Our branching-fraction
results suggest a large phase angle between the strong and electromagnetic
amplitudes describing the decay.Comment: 16 pages, 13 figures, the 2nd version, submitted to PR
First observation of the M1 transition
Using a sample of 106 million \psi(3686) events collected with the BESIII
detector at the BEPCII storage ring, we have made the first measurement of the
M1 transition between the radially excited charmonium S-wave spin-triplet and
the radially excited S-wave spin-singlet states: \psi(3686)\to\gamma\eta_c(2S).
Analyses of the processes \psi(2S)\to \gamma\eta_c(2S) with \eta_c(2S)\to
\K_S^0 K\pi and K^+K^-\pi^0 gave an \eta_c(2S) signal with a statistical
significance of greater than 10 standard deviations under a wide range of
assumptions about the signal and background properties. The data are used to
obtain measurements of the \eta_c(2S) mass (M(\eta_c(2S))=3637.6\pm
2.9_\mathrm{stat}\pm 1.6_\mathrm{sys} MeV/c^2), width
(\Gamma(\eta_c(2S))=16.9\pm 6.4_\mathrm{stat}\pm 4.8_\mathrm{sys} MeV), and the
product branching fraction (\BR(\psi(3686)\to \gamma\eta_c(2S))\times
\BR(\eta_c(2S)\to K\bar K\pi) = (1.30\pm 0.20_\mathrm{stat}\pm
0.30_\mathrm{sys})\times 10^{-5}). Combining our result with a BaBar
measurement of \BR(\eta_c(2S)\to K\bar K \pi), we find the branching fraction
of the M1 transition to be \BR(\psi(3686)\to\gamma\eta_c(2S)) = (6.8\pm
1.1_\mathrm{stat}\pm 4.5_\mathrm{sys})\times 10^{-4}.Comment: 7 pages, 1 figure, 1 tabl
Two-photon widths of the states and helicity analysis for \chi_{c2}\ar\gamma\gamma}
Based on a data sample of 106 M events collected with the
BESIII detector, the decays \psi^{\prime}\ar\gamma\chi_{c0, 2},\chi_{c0,
2}\ar\gamma\gamma are studied to determine the two-photon widths of the
states. The two-photon decay branching fractions are determined
to be {\cal B}(\chi_{c0}\ar\gamma\gamma) = (2.24\pm 0.19\pm 0.12\pm
0.08)\times 10^{-4} and {\cal B}(\chi_{c2}\ar\gamma\gamma) = (3.21\pm 0.18\pm
0.17\pm 0.13)\times 10^{-4}. From these, the two-photon widths are determined
to be keV,
keV, and
, where the uncertainties
are statistical, systematic, and those from the PDG {\cal
B}(\psi^{\prime}\ar\gamma\chi_{c0,2}) and errors,
respectively. The ratio of the two-photon widths for helicity and
helicity components in the decay \chi_{c2}\ar\gamma\gamma is
measured for the first time to be .Comment: 10 pages, 4 figure
ROS release by PPARβ/δ-null fibroblasts reduces tumor load through epithelial antioxidant response.
Tumor stroma has an active role in the initiation, growth, and propagation of many tumor types by secreting growth factors and modulating redox status of the microenvironment. Although PPARβ/δ in fibroblasts was shown to modulate oxidative stress in the wound microenvironment, there has been no evidence of a similar effect in the tumor stroma. Here, we present evidence of oxidative stress modulation by intestinal stromal PPARβ/δ, using a FSPCre-Pparb/d <sup>-/-</sup> mouse model and validated it with immortalized cell lines. The FSPCre-Pparb/d <sup>-/-</sup> mice developed fewer intestinal polyps and survived longer when compared with Pparb/d <sup>fl/fl</sup> mice. The pre-treatment of FSPCre-Pparb/d <sup>-/-</sup> and Pparb/d <sup>fl/fl</sup> with antioxidant N-acetyl-cysteine prior DSS-induced tumorigenesis resulted in lower tumor load. Gene expression analyses implicated an altered oxidative stress processes. Indeed, the FSPCre-Pparb/d <sup>-/-</sup> intestinal tumors have reduced oxidative stress than Pparb/d <sup>fl/fl</sup> tumors. Similarly, the colorectal cancer cells and human colon epithelial cells also experienced lower oxidative stress when co-cultured with fibroblasts depleted of PPARβ/δ expression. Therefore, our results establish a role for fibroblast PPARβ/δ in epithelial-mesenchymal communication for ROS homeostasis
Theoretical characterization of single-electron iodine-bond weak interactions in CH3…I-Y(Y = BH2, H, CH3, C2H3, C2H, CN, NC) systems
Psoriasis Regression Analysis of MHC Loci Identifies Shared Genetic Variants with Vitiligo
Psoriasis is a common inflammatory skin disease with genetic components of both immune system and the epidermis. PSOR1 locus (6q21) has been strongly associated with psoriasis; however, it is difficult to identify additional independent association due to strong linkage disequilibrium in the MHC region. We performed stepwise regression analyses of more than 3,000 SNPs in the MHC region genotyped using Human 610-Quad (Illumina) in 1,139 cases with psoriasis and 1,132 controls of Han Chinese population to search for additional independent association. With four regression models obtained, two SNPs rs9468925 in HLA-C/HLA-B and rs2858881 in HLA-DQA2 were repeatedly selected in all models, suggesting that multiple loci outside PSOR1 locus were associated with psoriasis. More importantly we find that rs9468925 in HLA-C/HLA-B is associated with both psoriasis and vitiligo, providing first important evidence that two major skin diseases share a common genetic locus in the MHC, and a basis for elucidating the molecular mechanism of skin disorders
The association between hantavirus infection and selenium deficiency in mainland China
Hemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses and transmitted by rodents is a significant public health problem in China, and occurs more frequently in selenium-deficient regions. To study the role of selenium concentration in HFRS incidence we used a multidisciplinary approach combining ecological analysis with preliminary experimental data. The incidence of HFRS in humans was about six times higher in severe selenium-deficient and double in moderate deficient areas compared to non-deficient areas. This association became statistically stronger after correction for other significant environment-related factors (low elevation, few grasslands, or an abundance of forests) and was independent of geographical scale by separate analyses for different climate regions. A case-control study of HFRS patients admitted to the hospital revealed increased activity and plasma levels of selenium binding proteins while selenium supplementation in vitro decreased viral replication in an endothelial cell model after infection with a low multiplicity of infection (MOI). Viral replication with a higher MOI was not affected by selenium supplementation. Our findings indicate that selenium deficiency may contribute to an increased prevalence of hantavirus infections in both humans and rodents. Future studies are needed to further examine the exact mechanism behind this observation before selenium supplementation in deficient areas could be implemented for HFRS prevention
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