15 research outputs found

    An Investigation into the Implications of Islamic Work Ethic (IWE) in the Workplace

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    There has been an increasing interest on the work ethics and its various aspects among the academicians and practitioners. This is partly because of the ethical scandals that have occurred in the recent years and got attention from media and public and therefore raised the questions regarding ethical standards of companies and its practical use in the business life. This interest has prompted several research into the topic both theoretical and practical levels. Although the studies have accumulated in the Western World, the studies coming from the developing countries are limited and thus call for the studies to further investigate the dynamics and implications of the work ethics. This study particularly pays attention to Islamic work ethic and aims to identify whether Islamic work ethic values differ across various demographic variables and firm characteristics. The study also investigates the relationship between the Islamic work ethic and innovation capability and firm performance. The study is supported with a field study conducted on the firms operating in KahramanmaraÅŸ in Turkey. The obtained data was analyzed by using Correlation, ANOVA, T-test and Regression in SPSS. The results showed that IWE values differ across some characteristic of the respondents and firms. The results also indicate the positive influence of IWE values on innovation capability and firm performance

    Can propolis be protective against ethanol-impaired anxiety and unconditional fear?

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    Alcohol metabolism produces acetaldehyde and free radicals which are source of an oxidatif stress. The oxidatif stress causes oxidatif damage on area of learning and memory thus depresses learning and memory processes. Propolis is a component of honeybee that has been used extensively for folk medicine for centuries due to its several biological and pharmacological properties. This work is carried out in order to investigate whether propolis treatment could reverse metabolic alterations on anxiety induced by alcohol. [Med-Science 2015; 4(1.000): 1885-94

    Unilateral Ectopic Kidney in the Pelvis and Right Undescended Testicle: A Case Report

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    Urinary system anomalies are cases that can be encountered in the clinic. In the anatomy laboratory, we observed that a different vessel was separated from the aortic bifurcation during routine dissection. As a result of the vascular follow-up, we determined that the male cadaver had a pelvic localized ectopic kidney. As a result of the vascularization, we found that there is an ectopic kidney with pelvic location in the male cadaver. One of the most common forms of congenital renal ectopia is pelvic localized ectopic kidney. When the dissection was detailed, the right undescended testicle accompanying the right ectopic kidney was detected. In conclusion we are of the opinion that knowing such anomalies and variations will guide physicians before surgical procedures

    Protective Effect of Quercetin Against Oxidative Stressinduced Toxicity Associated With Doxorubicin and Cyclophosphamide in Rat Kidney and Liver Tissue

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    WOS: 000397993100006PubMed ID: 28270644Introduction. Doxorubicin and cyclophosphamide are widely used anticancer drugs with substantial toxicity in noncancerous tissue resulting from oxidative damage. Quercetin is a potent antioxidant compound. We hypothesized that quercetin administration would ameliorate the toxic effects of doxorubicin and cyclophosphamide prior to pregnancy. Materials and Methods. Cyclophosphamide, 27 mg/kg, and doxorubicin, 1.8 mg/kg, were administered to rats as intraperitoneal doses once every 3 weeks for a total of 10 weeks with or without concurrent treatment with quercetin, 10 mg/kg/d. Oxidative stress parameters were evaluated in maternal kidney and liver tissues after gestation. Results. Doxorubicin was associated with elevated kidney tissue malondialdehyde relative to the controls and quercetin only treatment (P < .05). Both cyclophosphamide and doxorubicin were associated with elevated malondialdehyde levels in the liver tissue (P < .05). Doxorubicin treatment was associated with decreased liver glutathione peroxidase (P < .05). Quercetin treatment suppressed the accumulation of malondialdehyde and increased glutathione peroxidase levels during doxorubicin and cyclophosphamide treatment (P < . 05) Conclusions. Treatment with quercetin in patients receiving doxorubicin and cyclophosphamide results in therapeutic restoration of homeostatic expression of the antioxidant parameters, reducing oxidative damage to the liver and kidney

    EFFECTS OF ACUTE MODERATE AND STRENUOUS EXERCISE BOUTS ON IL-17 PRODUCTION AND INFLAMMATORY RESPONSE IN TRAINED RATS

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    In this study, we aimed to compare the effects of a single bout of acute moderate and strenuous running exercise on the production of interleukin-17 (IL-17), interleukin-6 (IL-6), interleukin-1 receptor antagonist (IL-1ra) and inflammatory response of skeletal muscles in regularly trained rats. Eight week old rats were trained by treadmill running 5 days per week for 13 weeks at the durations of 30 min (moderate) and 60 min (strenuous). Two days after the last training session, the animals were subjected to a single bout of moderate or strenuous exercise and serum samples were analyzed for IL-17, IL-6, IL-1ra levels and myeloperoxidase (MPO) activity of gastrocnemius muscle were determined. IL-17 level significantly increased in strenuous exercise group when compared to that of sedentary controls (p < 0.01), On the other hand, only in the moderate exercise group, there was a negative correlation between IL-6 and IL-17 levels (r = - 0.857 and p = 0.014). In conclusion, acute single bout of strenuous exercise increased IL-17 production in trained rats and, this cytokine may be involved in inflammatory process of skeletal muscle

    Hepatoprotective effect of royal jelly, grape seed extract, and Lycium barbarum against diethylnitrosamine-induced liver toxicity in rats

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    Aim: We aimed to investigate, the effects of royal jelly (RJ), grape seed extract (GSE), and Lycium barbarum extract (LBAE) against diethylnitrosamine (DEN) induced hepatotoxicity, in experimental animal model. Material and Methods: Fifty female Sprague Dawley rats were divided into five groups (n=10): Control, DEN, DEN+RJ, DEN+GSE, DEN+LBAE. DEN administrated groups were intraperitoneally (i.p.) injected with three separate administration of DEN (200 mg/kg), on the zero, fifteenth and thirtieth treatment day. Then 100 mg/kg of RJ was given to DEN+RJ group, 100 mg/kg of GSE was given to DEN+GSE group, and 400 mg/kg LBAE was given to DEN+LBAE group with the daily drinking water from day 0 for 16 weeks. Histopathologic alterations including apoptotic changes of liver were evaluated. Results: RJ, GSE, and LBAE treatments significantly reduced weight loss induced by DEN. DEN administrated rats significantly increases malondialdehyde (MDA) level. It also efficiently decreases glutathione (GSH) level and catalase (CAT), superoxide dismutase (SOD) activity. These results were significantly ameliorated by dietary supplements (p GSE > LBAE. Our results indicated that RJ, GSE and LBAE might be useful for prevention of hepatotoxicity induced by DEN via ameliorative effects on biochemical and oxidative stress indices

    The Effect of Sterilization Methods of Endoscopic Instruments on the Body: A Study on Rat Model

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    Purpose: Laparoscopy is widely used in many surgical areas for diagnosis and treatment. The need for sterilization of reusable instruments is an important issue. Ensuring patient safety, preventing infection, and protecting the functionality of the instruments are the most important points to be considered. We aimed to investigate two sterilization methods and their effects generated by their distribution into intra-abdominal tissues during insufflation. Materials and Methods: 21 rats were used in the study. The Control Group (Group 1) received anesthesia for 1 hour; Group 2 (Glutaraldehyde (GA)-Pneumoperitoneum Group) received anesthesia for 1 hour; Group 3 (Ethylene Oxide (EO)-Pneumoperitoneum Group) received anesthesia for 1 hour. After 24 hours, the animals were sacrificed, and the kidneys and omentum of the animals were analyzed in a histopathological manner. Blood samples were analyzed at preoperative 24th hour and at postoperative 24th hour. Results: There was a statistically significant difference in omentum, endothelium, and glomerular scores between the groups (p < 0.001 for all groups). Endothelial and glomerular scores were different at a statistically significant level in the EO and GA groups compared to the Control Group. The total score was higher at a statistically significant level in the EO and GA groups compared to the Control Group (p < 0.001 for both groups). Conclusion: It was determined in our study that sterilization methods such as EO and GA cause damage in intra-abdominal tissues. In the light of these results, we consider that the most ideal laparoscopic surgery set is the single-use laparoscopy set. However, this does not seem possible especially in developing countries in practice

    The effects of prolonged CO 2 insufflation on kidney function in a rat pneumoperitoneum model

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    Introduction : Pneumoperitoneum (PP) is known to cause ischemia in kidneys and other intra-abdominal organs because of decreased splanchnic blood flow. Aim : We aimed to determine the degree of renal injury that occurs due to a PP and prolonged PP. We measured renal injury biomarkers and made a histopathological evaluation to estimate the degree of injury and assessed the correlation of biomarkers with histopathological findings. Material and methods : Twenty-one female Sprague Dawley rats were separated randomly into three groups. Group 1 was the control group and was given anesthesia for 3 h. In group 2, a PP was administered under anesthesia for 1 h. A pneumoperitoneum was administered under anesthesia to animals in group 3 for 3 h. Results : Pathological analysis showed a significant statistical difference between the 3 groups. In particular, neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C (Cys C) levels at the 24th h and preoperative mean urea levels showed a significant difference between the groups. The 24th-hour NGAL level in group 3 was significantly higher than that of group 1. The preoperative Cys C level was higher in group 1 than in either group 2 or 3. Cys C was decreased significantly in group 1 and increased significantly in both groups 2 and 3. Conclusions : The increase in NGAL and Cys C levels directly correlated with the duration of PP and intra-abdominal pressure, and they are therefore good biomarkers in diagnosing acute renal injury in the early phase. Serum creatinine level is not a good biomarker in the early phase of renal injury
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