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    <p>Gestational-age specific risks<sup><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0155692#t004fn001" target="_blank">*</a></sup> of adverse perinatal outcomes comparing cesarean-section (130,808 infants) vs. vaginal (n = 232,812 infants) deliveries in twin pregnancies.</p

    Maternal, pregnancy and newborn characteristics in diabetic versus non-diabetic twin pregnancies in the study population, U.S. 1995-2000 [16].

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    <p>Data presented are n (%). P values are from Chi-square tests for differences between diabetic and non-diabetic pregnancies.</p>*<p>SGA=Small-for-gestational-age <10<sup>th</sup> percentile, LGA=large-for-gestational-age >90<sup>th</sup> percentile, according to birth weight percentiles in the study cohort.</p>ʃ<p>Anyone or more of the following conditions: chronic hypertension, heart disease, acute or chronic lung disease, renal disease, genital herpes and RH sensitization.</p>ʂ<p>There were significant numbers (>10%) of missing information on smoking (17.8% missing) and mode of delivery (36.6% missing). The percentages of smokers and caesarean section were based on births without missing information.</p

    Neonatal mortality in diabetic versus non-diabetic twin pregnancies, U.S. matched multiple birth data 1995-2000 [16].

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    <p>HR = Hazard ratio; CI = confidence interval</p>*<p>Hazard ratios adjusted for maternal race, age, education, marital status, parity, smoking, other maternal major illnesses, fetal sex, mode of delivery and twin-cluster level dependence in Cox proportional hazard models.</p>ʃ<p>Gestational age group-specific mortality rates and hazard ratios were calculated using the fetuses-at-risk denominator including all fetuses at risk of death (both born and unborn babies).</p>ʂ<p>P value in test for interaction with diabetes in pregnancy in relation to the risk of neonatal mortality.</p

    Perinatal mortality in diabetic versus non-diabetic twin pregnancies, U.S. matched multiple birth data 1995-2000 [16].

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    <p>HR = Hazard ratio; CI = confidence interval</p>*<p>Hazard ratios adjusted for maternal race, age, education, marital status, parity, smoking, other maternal major illnesses, fetal sex, mode of delivery and twin-cluster level dependence in Cox proportional hazard models.</p>ʃ<p>Gestational age group-specific mortality rates and hazard ratios were calculated using the fetuses-at-risk denominator including all fetuses at risk of death (both born and unborn babies).</p>ʂ<p>P value in test for interaction with diabetes in pregnancy in relation to the risk of perinatal mortality </p

    The adjusted hazard ratios of the composite primary outcome (perinatal death or severe neonatal morbidity) comparing cesarean vs vaginal deliveries over gestational age (weeks) in all twins, first twins and second twins.

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    <p>The hazard ratios were from Cox regression models adjusting for the propensity to C-section (through weighting by the inverse of the propensity score), birth weight, birth weight discordance (>25%) in twins, infant sex, same-sex twin or not, and twin cluster-level dependence; the unit of analysis is the infant. The error bars represent the 95% confidence intervals.</p

    Composite adverse perinatal outcome comparing cesarean-section (n = 41,020 infants) vs. vaginal (n = 71,804 infants) deliveries in the analyses restricted to different-sex (dichorionic) twin pregnancies without major maternal pathologies<sup>a</sup>.

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    <p>Composite adverse perinatal outcome comparing cesarean-section (n = 41,020 infants) vs. vaginal (n = 71,804 infants) deliveries in the analyses restricted to different-sex (dichorionic) twin pregnancies without major maternal pathologies<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0155692#t005fn001" target="_blank"><sup>a</sup></a>.</p

    Maternal characteristics by intended mode of delivery * in twin pregnancies without malformations (n = 181,810), U.S. 1995–2000.

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    <p>Maternal characteristics by intended mode of delivery * in twin pregnancies without malformations (n = 181,810), U.S. 1995–2000.</p

    Classifications of intended mode of delivery, based recorded mode of delivery in twin pairs (Twin A-Twin B) and evidence of trial of labor in the twin pregnancy study cohort.

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    <p>Classifications of intended mode of delivery, based recorded mode of delivery in twin pairs (Twin A-Twin B) and evidence of trial of labor in the twin pregnancy study cohort.</p
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