1,280 research outputs found
Exposure to endocrine-disrupting chemicals in the USA: a population-based disease burden and cost analysis
Background Endocrine-disrupting chemicals (EDCs) contribute to disease and dysfunction and incur high associated costs (>1% of the gross domestic product [GDP] in the European Union). Exposure to EDCs varies widely between the USA and Europe because of differences in regulations and, therefore, we aimed to quantify disease burdens and related economic costs to allow comparison. Methods We used existing models for assessing epidemiological and toxicological studies to reach consensus on probabilities of causation for 15 exposure–response relations between substances and disorders. We used Monte Carlo methods to produce realistic probability ranges for costs across the exposure–response relation, taking into account uncertainties. Estimates were made based on population and costs in the USA in 2010. Costs for the European Union were converted to US1·33). Findings The disease costs of EDCs were much higher in the USA than in Europe (217 billion [1·28%]). The difference was driven mainly by intelligence quotient (IQ) points loss and intellectual disability due to polybrominated diphenyl ethers (11 million IQ points lost and 43 000 cases costing 12·6 billion in the European Union). Accounting for probability of causation, in the European Union, organophosphate pesticides were the largest contributor to costs associated with EDC exposure (42 billion). Interpretation EDC exposure in the USA contributes to disease and dysfunction, with annual costs taking up more than 2% of the GDP. Differences from the European Union suggest the need for improved screening for chemical disruption to endocrine systems and proactive prevention. Funding Endocrine Society, Ralph S French Charitable Foundation, and Broad Reach Foundation. © 2016 Elsevier Lt
Correlated /\c-/\cbar production in e+e- annihilations at sqrt{s}~10.5 GeV
Using 13.6/fb of continuum two-jet e+e- -> ccbar events collected with the
CLEO detector, we have searched for baryon number correlations at the primary
quark level. We have measured the likelihood for a /\c+ charmed baryon to be
produced in the hemisphere opposite a /\c- relative to the likelihood for a
/\c+ charmed baryon to be produced opposite an anticharmed meson Dbar; in all
cases, the reconstructed hadrons must have momentum greater than 2.3 GeV/c. We
find that, given a /\c- (reconstructed in five different decay modes), a /\c+
is observed in the opposite hemisphere (0.72+/-0.11)% of the time (not
corrected for efficiency). By contrast, given a Dbar in one hemisphere, a /\c+
is observed in the opposite hemisphere only (0.21+/-0.02)% of the time.
Normalized to the total number of either /\c- or Dbar ``tags'', it is therefore
3.52+/-0.45+/-0.42 times more likely to find a /\c+ opposite a /\c- than a Dbar
meson. This enhancement is not observed in the JETSET 7.3 e+e- -> ccbar Monte
Carlo simulation.Comment: 19 pages, Latex, one figure separat
Rate Measurement of and Constraints on Mixing
We present an observation and rate measurement of the decay D0 -> K+pi-pi0
produced in 9/fb of e+e- collisions near the Upsilon(4S) resonance. The signal
is inconsistent with an upward fluctuation of the background by 4.9 standard
deviations. We measured the rate of D0 -> K+pi-pi0 normalized to the rate of
D0bar -> K+pi-pi0 to be 0.0043 +0.0011 -0.0010 (stat) +/- 0.0007 (syst). This
decay can be produced by doubly-Cabibbo-suppressed decays or by the D0 evolving
into a D0bar through mixing, followed by a Cabibbo-favored decay to K+pi-pi0.
We also found the CP asymmetry A=(8 +25 -22)% to be consistent with zero.Comment: 10 pages postscript, also available through
http://w4.lns.cornell.edu/public/CLN
Study of 3-prong Hadronic Decays with Charged Kaons
Using a sample of 4.7/fb integrated luminosity accumulated with the CLEO-II
detector at the Cornell Electron Storage Ring (CESR), we have measured the
branching fractions of the tau lepton into and relative to and relative to . The relative branching fractions are: (5.16+-0.20+-0.50)*,
(1.52+-0.14+-0.29)*, (2.54+-0.44+-0.39)* and at 95%
C.L., respectively. Coupled with additional experimental information, we use
our results to extract information on the structure of three-prong tau decays
to charged kaons.Comment: 16 pages postscript file also available through
http://w4.lns.cornell.edu/public/CLN
First Observation of
We report on a study of exclusive radiative decays of the Upsilon(1S)
resonance collected with the CLEO-II detector operating at CESR. We present the
first observation of the radiative decays Upsilon(1S)->gamma pi+pi- and
Upsilon(1S)->gamma pi0pi0. For the dipion mass regime m(pipi)>1.0 GeV, we
obtain Br(Upsilon(1S)->gamma pi+pi-=(6.3+/-1.2+/-1.3) x 10^(-5), and
Br(Upsilon(1S)->gamma pi0pi0=(1.7+/-0.6+/-0.3) x 10^(-5). The observed gamma
pipi events are consistent with the hypothesis Upsilon(1S)->gamma f2(1270).Comment: 9 pages, postscript file also available through
http://w4.lns.cornell.edu/public/CLN
Measurement of using Partila Reconstruction of
We present a measurement of the absolute branching fraction for using the reconstruction of the decay chain , where only the lepton and the low-momentum pion from
the are detected. With data collected by the CLEO II detector at the
Cornell Electron Storage Ring, we have determined .Comment: 10 page postscript file, postscript file also available through
http://w4.lns.cornell.edu/public/CLN
Update of the Search for the Neutrinoless Decay
We present an update of the search for the lepton family number violating
decay using a complete CLEO II data sample of 12.6 million
pairs. No evidence of a signal has been found and the
corresponding upper limit is \BR(\tau \to \mu\gamma) < 1.0 \times 10^{-6}
at 90% CL, significantly smaller than previous limits. All quoted results are
preliminary.Comment: 9 pages postscript, also available through
http://w4.lns.cornell.edu/public/CLN
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