101 research outputs found

    Microstructure development during thermomechanical treatment of Al-Mg-Si alloy

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    The effect of natural aging and 95% cold deformation on the microstructure evolution and aging characteristics in commercial Al - 1 mass % Mg2Si alloy subjected to thermomechanical treatment (TMT) was examined. Transmission electron microscopy observations, tensile tests and electrical conductivity measurements were carried out in order to correlate microstructural features to properties on each TMT step. It was established that pre-aging at room temperature affected the morphology of dislocation structure induced by next cold deformation. The observed transition from cellular to homogenous dislocation distribution was explained by the different stability of zones produced by pre-aging of different duration. Natural aging suppressed recovery processes during post-deformation artificial aging, especially after prolonged storage after quenching and at lower aging temperature. It influenced the morphology of precipitates produced by post deformation artificial aging also. The overall effect of TMT involving prior-deformation natural aging in the scheme, on hardness, tensile properties and electrical conductivity is discussed based on experimental microstruture observations

    CLINICAL, ELECTROENCEPHALOGRAPHIC AND RHEOENCEPHALOGRAPHIC CORRELATIONS IN RELATIVES OF STROKE PATIENTS

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    OR1 EXAMINING ASSOCIATION BETWEEN PATIENT-REPORTED OUTCOMES AND CLINICAL OUTCOMES USING PROBIT REGRESSION ANALYSIS

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    Optimal Cutting Problem

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    One of the tasks of the Construction office of company STOBET Ltd is to create large sheets of paper containing a lot of objects describing a building construction as tables, charts, drawings, etc. For this reason it is necessary to arrange the small patterns in a given long sheet of paper with a minimum wastage. Another task of the company is to provide a way of cutting a stock material, e.g. given standard steel rods, into different number of smaller sized details in a way that minimizes the wasted material

    Relationships between changes in pain severity and other patient-reported outcomes: an analysis in patients with posttraumatic peripheral neuropathic pain

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    <p>Abstract</p> <p>Background</p> <p>The objective of this study is to use the pain numeric rating scale (NRS) to evaluate associations between change in pain severity and changes in sleep, function, and mood assessed via patient-reported outcomes (PROs) in patients with posttraumatic pain.</p> <p>Methods</p> <p>This is a secondary analysis of a clinical trial evaluating pregabalin in patients with posttraumatic peripheral neuropathic pain (N = 254). Regression models were used to determine associations between changes in pain (0-10 NRS) as the predictor and scores on the following PRO measures as the outcome: Pain Interference Index; Hospital Anxiety and Depression Scale anxiety and depression subscales; Medical Outcomes Study-Sleep Scale 9-item Sleep Problems Index and Sleep Disturbance subscale; and Daily Sleep Interference Scale (0-10 NRS).</p> <p>Results</p> <p>Change in pain severity showed clear, direct relationships with changes in function, anxiety, depression, and sleep PROs, all of which were statistically significant (<it>P </it><.001). Results from subgroup analyses (≥30% or ≥50% pain responders, pregabalin or placebo treatment, age ≤ 51 years or > 51 years) tended to be consistent with results from the overall sample.</p> <p>Conclusions</p> <p>Overall, a direct relationship exists between pain and various aspects of patient's well-being and functioning, which can provide a quantitative assessment of how improvements in pain may be expected to relate to other patient outcomes. (<url>http://ClinicalTrials.gov</url> Identifier number NCT00292188; EudraCT #2005-003048-78).</p

    Genetic relatedness of infecting and reinfecting respiratory syncytial virus strains identified in a birth cohort from rural Kenya

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    Background: Respiratory syncytial virus (RSV) reinfects individuals repeatedly. The extent to which this is a consequence of RSV antigenic diversity is unclear. Methods: Six-hundred thirty-five children from rural Kenya were closely monitored for RSV infection from birth through 3 consecutive RSV epidemics. RSV infections were identified by immunofluorescence testing of nasal washing samples collected during acute respiratory illnesses, typed into group A and B, and sequenced in the attachment (G) protein. A positive sample separated from a previous positive by ≥14 days was defined as a reinfection a priori. Results: Phylogenetic analysis was undertaken for 325 (80%) of 409 identified infections, including 53 (64%) of 83 reinfections. Heterologous group reinfections were observed in 28 episodes, and homologous group reinfections were observed in 25 episodes; 10 involved homologous genotypes, 5 showed no amino acid changes, and 3 were separated by 21–24 days and were potentially persistent infections. The temporal distribution of genotypes among reinfections did not differ from that of single infections. Conclusions: The vast majority of infection and reinfection pairs differed by group, genotype, or G amino acid sequence (ie, comprised distinct viruses). The extent to which this is a consequence of immune memory of infection history or prevalent diversity remains unclear
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