Stability and Hopf bifurcation of a ratio-dependent predator-prey model with time delay and stage structure

In this paper, a ratio-dependent predator-prey model described by Holling type II functional response with time delay and stage structure for the prey is investigated. By analyzing the corresponding characteristic equations, the local stability of the coexistence equilibrium of the model is discussed and the existence of Hopf bifurcations at the coexistence equilibrium is established. By using the persistence theory on infinite dimensional systems, it is proven that the system is permanent if the coexistence equilibrium exists. By introducing some new lemmas and the comparison theorem, sufficient conditions are obtained for the global stability of the coexistence equilibrium. Numerical simulations are carried out to illustrate the main results

Pilot Investigation of Coal Chemical Wastewater Containing Phenol by Pervaporation Process

Coal chemical wastewater contains a large number of industrial raw materials, such as phenol, resulting in difficulty as target to be treated and the resource waste as industrial raw materials. A pilot pervaporation process is investigated to separate and recycle phenols from coal chemical wastewater to reduce the follow-up biochemical processing load. Operation parameters which affect removing and recovering efficiency are studied, such as temperature, flow rate and downstream pressure. Phenol removal efficiency could reach 50% under the conditions of 70o C, 210 L/h and 3000 Pa. The system could continuously run for 20 cycles. Furthermore, the pervaporation procedure could be enhanced when pumped with gas which made the removal efficiency up to 66%

Boron neutron capture therapy induces cell cycle arrest and cell apoptosis of glioma stem/progenitor cells in vitro

BACKGROUND: Glioma stem cells in the quiescent state are resistant to clinical radiation therapy. An almost inevitable glioma recurrence is due to the persistence of these cells. The high linear energy transfer associated with boron neutron capture therapy (BNCT) could kill quiescent and proliferative cells. METHODS: The present study aimed to evaluate the effects of BNCT on glioma stem/progenitor cells in vitro. The damage induced by BNCT was assessed using cell cycle progression, apoptotic cell ratio and apoptosis-associated proteins expression. RESULTS: The surviving fraction and cell viability of glioma stem/progenitor cells were decreased compared with differentiated glioma cells using the same boronophenylalanine pretreatment and the same dose of neutron flux. BNCT induced cell cycle arrest in the G2/M phase and cell apoptosis via the mitochondrial pathway, with changes in the expression of associated proteins. CONCLUSIONS: Glioma stem/progenitor cells, which are resistant to current clinical radiotherapy, could be effectively killed by BNCT in vitro via cell cycle arrest and apoptosis using a prolonged neutron irradiation, although radiosensitivity of glioma stem/progenitor cells was decreased compared with differentiated glioma cells when using the same dose of thermal neutron exposure and boronophenylalanine pretreatment. Thus, BNCT could offer an appreciable therapeutic advantage to prevent tumor recurrence, and may become a promising treatment in recurrent glioma

A method to monitor IGBT module bond wire failure using on-state voltage separation strategy

On-state voltage is an important thermal parameter for insulated gate bipolar transistor (IGBT) modules. It is employed widely to predict failure in IGBT module bond wires. However, due to restrictions in work environments and measurement methods, it is difficult to ensure the measurement accuracy for the on-state voltage under practical working conditions. To address this problem, an on-state voltage separation strategy is proposed for the IGBT modules with respect to the influence of collector current (Ic) and junction temperature (Tj). This method involves the separation of the on-state voltage into a dependent part and two independent parts during the IGBT module bond wire prediction. Based on the proposed separation strategy, the independent parts in the failure prediction can be removed, making it possible to directly monitor the voltage variations caused by bond wire failure. The experimental results demonstrate that the proposed diagnosis strategy can accurately predict the bond wire failure stage in an IGBT module under different conditions

Operating Conditions of Hollow Fiber Supported Liquid Membrane for Phenol Extraction from Coal Gasification Wastewater

The extraction and recycling of phenol from high concentration coal gasification wastewater has been studied using polypropylene (PP) hollow fiber membrane and polyvinylidene fluoride (PVDF) hollow fiber membrane as liquid membrane support, the mixture of tributyl phosphate (TBP) and kerosene as liquid membrane phase, and sodium hydroxide as stripping agent in the process of extraction. The experiments investigated the effect of the operating conditions of the hollow fiber supported liquid membrane, such as aqueous phase temperature and the connection forms of membrane modules, on the extraction efficiency of phenol from high concentration coal gasification wastewater. The conclusions obtained from lab scale experiments provided guidance for scale-up experiments. So, in the scale-up experiments, three membrane modules connected in parallel, then three membrane modules connected in series were used to increase the treatment capacity and improve the treatment effect, under the operating conditions of wastewater temperature 20 ˚C, PH 7.5~8.1, flow rate 100 L/h and the concentration of stripping phase 0.1 mol/L, stripping phase flow rate 50 L/h, the extraction efficiency of the PP-TBP supported liquid membrane system was 87.02% and the phenol concentration of effluent was 218.14mg/L. And the phenol concentration of effluent met the requirements of further biodegradation treatment

The Prevalence and Risk Factors of Diabetic Retinopathy: Screening and Prophylaxis Project in 6 Provinces of China.

Purpose: To investigate the prevalence and associated factors of diabetic retinopathy (DR) and advanced DR in Chinese adults with diabetes mellitus (DM). Patients and Methods: A cross-sectional study was performed on 4831 diabetic patients from 24 hospitals from April 2018 to July 2020. Non-mydriatic fundus of patients were interpreted by an artificial intelligence (AI) system. Fundus photos that were unsuitable for AI interpretation were interpreted by two ophthalmologists trained by one expert ophthalmologist at Beijing Tongren Hospital. Medical history, height, weight, body mass index (BMI), glycosylated hemoglobin (HbA1c), blood pressure, and laboratory examinations were recorded. Results: A total of 4831 DM patients were included in this study. The prevalence of DR and advanced DR in the diabetic population was 31.8% and 6.6%, respectively. In multiple logistic regression analysis, male (odds ratio [OR], 1.39), duration of diabetes (OR, 1.05), HbA1c (OR, 1.11), farmer (OR, 1.39), insulin treatment (OR, 1.61), region (northern, OR, 1.78; rural, OR, 6.96), and presence of other diabetic complications (OR: 2.03) were associated with increased odds of DR. The factors associated with increased odds of advanced DR included poor glycemic control (HbA1c > 7.0%) (OR, 2.58), insulin treatment (OR, 1.73), longer duration of diabetes (OR, 3.66), rural region (OR, 4.84), and presence of other diabetic complications (OR, 2.36), but overweight (BMI > 25 kg/m2) (OR, 0.61) was associated with reduced odds of advanced DR. Conclusion: This study shows that the prevalence of DR is very high in Chinese adults with DM, highlighting the necessity of early diabetic retinal screening