Citations Driven by Social Connections? A Multi-Layer Representation of Coauthorship Networks

To what extent is the citation rate of new papers influenced by the past social relations of their authors? To answer this question, we present a data-driven analysis of nine different physics journals. Our analysis is based on a two-layer network representation constructed from two large-scale data sets, INSPIREHEP and APS. The social layer contains authors as nodes and coauthorship relations as links. This allows us to quantify the social relations of each author, prior to the publication of a new paper. The publication layer contains papers as nodes and citations between papers as links. This layer allows us to quantify scientific attention as measured by the change of the citation rate over time. We particularly study how this change depends on the social relations of their authors, prior to publication. We find that on average the maximum value of the citation rate is reached sooner for authors who either published more papers, or who had more coauthors in previous papers. We also find that for these authors the decay in the citation rate is faster, meaning that their papers are forgotten sooner

A holistic approach for the selection of forensic DNA swabs.

In the present study, we compared the performance of five different ISO 18385 certified forensic swabs for DNA sampling in practice over a time period of five months. Comparisons were made for DNA profiling success rates, measured as the percentage of CODIS (Combined DNA Index System) suitable profiles as well as for practical suitability during sampling at the scene, measured through a survey among collaborators. More than forty members of our crime scene investigation (CSI) unit took part in the test series and provided structured feedback concerning different aspects of swab handling. A total number of 1094 "touch" DNA samples have been subjected to DNA analysis. Swabs performed significantly different in terms of DNA profiling success rates. We also observed significant differences in DNA extraction efficiency between swabs. The evaluation by the collaborators of various aspects of handling differed significantly between swabs. We can assume that a more convenient handling decreases the risk of contamination or sample mislabelling and increases sampling efficiency and staff satisfaction. Our results demonstrate that the selection of disposable sampling devices such as forensic swabs for DNA sampling should be made based on a holistic approach. To be able to select the best performing swab for a given combination of CSI and DNA laboratory procedures, it might not be sufficient to only perform DNA extraction comparisons and trace sampling under controlled laboratory conditions

Rapid Colonization with Methicillin-Resistant Coagulase-Negative Staphylococci After Surgery

Background: Antimicrobial resistance may compromise the efficacy of antibiotic prophylaxis before surgery. The aim of this study was to measure susceptibility and clonal distribution of coagulase-negative staphylococci (CoNS) colonizing the skin around the surgery access site before and after the procedure. Methods: From March to September 2004, a series of 140 patients undergoing elective major abdominal surgery were screened for CoNS colonization at admission and 5days after surgery. All isolates were tested for antibiotic susceptibility and genotyped by pulsed-field gel electrophoresis (PFGE). Results: Colonization rates with CoNS at admission and after surgery were 85% and 55%, respectively. The methicillin-resistant CoNS rate increased from 20% at admission to 47% after surgery (P=0.001). The PFGE pattern after surgery revealed more patients colonized with identical clones: 8/140 patients (8/119 strains) and 26/140 patients (26/77 strains), respectively (P<0.001). Conclusions: Our results suggest rapid recolonization of disinfected skin by resistant nosocomial CoNS. Larger studies, preferably among orthopedic or cardiovascular patients, are required to clarify whether standard antibiotic prophylaxis with first- or second-generation cephalosporins for CoNS infections may be compromised if the patient requires an additional intervention 5days or more after the initial surger

Quantifying cup overhang after total hip arthroplasty: standardized measurement using reformatted computed tomography and association of overhang distance with iliopsoas impingement

OBJECTIVES Currently, there is no standardized measurement method for evaluating cup overhang (CO) in patients undergoing total hip arthroplasty (THA). We propose a novel, standardized method of measuring overhang distance in patients following primary total hip arthroplasty (THA) on computed tomography (CT) images after multiplanar reformation and compare it to a previously proposed measurement method on sagittal CT images. MATERIALS AND METHODS This retrospective study included patients who underwent primary THA with an anterior approach. Patients with cup overhang (CO) and iliopsoas impingement (IPI) were identified by clinical and imaging data. Uncorrected overhang distance (OD$_{u}$) was evaluated on orthogonal sagittal CT images while corrected overhang distance (OD$_{c}$) was evaluated on reformatted sagittal CT images corrected for pelvic rotation and aligned with the plane of the cup face. RESULTS Out of 220 patients with THA, 23 patients (10.4%) with CO and 16 patients (7.3%) with IPI were identified. CO was significantly associated to IPI (p < 0.001). The inter- and intrareader agreement was almost perfect for OD$_{c}$ (κ = 0.822, κ = 0.850), whereas it was fair and moderate for OD$_{u}$ (κ = 0.391, κ = 0.455), respectively. The discriminative ability of OD$_{c}$ was excellent (area under the curve (AUC) = 0.909 (95% confidence interval (CI) 0.784-1.000)) in the receiver operating characteristic analysis. Conversely, AUC for OD$_{u}$ was poor, measuring 0.677 (95% CI 0.433-0.921). CONCLUSION We implemented a novel measurement method for CT images reformatted at the plane of the cup face to assess overhang distance in patients with CO following THA. CLINICAL RELEVANCE STATEMENT While further validation is necessary, the proposed method is characterized by its high reproducibility and might be used to predict the occurrence of iliopsoas impingement in patients with cup overhang following total hip arthroplasty. KEY POINTS • A novel, standardized method of measuring cup overhang distance in patients following primary total hip arthroplasty on CT images is proposed. • Cup overhang was associated to iliopsoas impingement. The proposed method was reproducible and showed excellent prediction of iliopsoas impingement in patients with cup overhang. • This method can be implemented in clinical practice when assessing CT images of patients with cup overhang for iliopsoas impingement

Classification of trochlear dysplasia as predictor of clinical outcome after trochleoplasty

Purpose: Sulcus-deepening trochleoplasty restores the trochlear groove in patients with patellofemoral instability and underlying trochlear dysplasia. There are types of dysplasia both with (B and D) and without (A and C) a supratrochlear spur. The aim of this study was to identify influencing factors for the clinical outcome following trochleoplasty. Methods: Forty-four knees in 38 patients who underwent trochleoplasty for instability (type A in 9, B in 15, C in 9 and D in 11 knees) were assessed clinically with the Kujala score and radiologically with radiographs and MRI. The median follow-up was 4 (2-7.8) years. Results: At follow-up, the median Kujala score had improved from 68 (29-84) to 90 (42-100) points (P<0.001). Instability (P<0.001) and pain (P=0.027) decreased significantly, but in 3 knees, pain was worse postoperatively. Twenty-seven knees were ranked as excellent, 10 as good, 2 as fair and 5 as poor. Overall, dysplasia types B and D benefited more from surgery than types A and C. The postoperative MRI revealed no chondrolysis or subchondral necrosis, but deterioration of cartilage on the lateral trochlear facet was identified. Conclusion: Trochleoplasty is a useful and reliable surgical technique to improve patellofemoral instability in patients with a dysplastic trochlea. While improved stability is predictable, pain is less predictable and may even increase following surgery. The overall results were directly dependent on the type of the dysplasia, with a significantly better clinical outcome in type B and D. The clinical relevance of this study is that severe dysplasia can successfully be treated with trochleoplasty. Level of evidence: II

Influence of thoracic epidural analgesia on postoperative pain relief and ileus after laparoscopic colorectal resection: Benefit with epidural analgesia

Background: Thoracic epidural analgesia (TEA) provides superior analgesia with a lower incidence of postoperative ileus when compared with systemic opiate analgesia in open colorectal surgery. However, in laparoscopic colorectal surgery the role of TEA is not well defined. This prospective observational study investigates the influence of TEA in laparoscopic colorectal resections. Methods: All patients undergoing colorectal resection between November 2004 and February 2007 were assessed for inclusion into a prospective randomized trial investigating the influence of bisacodyl on postoperative ileus. All patients treated by laparoscopic resection from this collective were eligible for the present study. Primary endpoints were use of analgesics and visual analogue scale (VAS) pain scores. Secondary endpoint concerned full gastrointestinal recovery, defined as the mean time to the occurrence of the following three events (GI-3): first flatus passed, first defecation, and first solid food tolerated. Results: 75 patients underwent laparoscopic colorectal resection, 39 in the TEA group and 36 in the non-TEA group. Patients with TEA required significantly less analgesics (metamizol median 3.0g [0-32g] versus 13.8g [0-28g] (p<0.001); opioids mean 12mg [±2.8mg standard error of mean, SEM] versus 103mg [±18.2mg SEM] (p<0.001). VAS scores were significantly lower in the TEA group (overall mean 1.67 [± 0.2 SEM] versus 2.58 [±0.2 SEM]; p=0.004). Mean time to gastrointestinal recovery (GI-3) was significantly shorter (2.96 [±0.2 SEM] days versus 3.81 [±0.3 SEM] days; p=0.025). Analysis of the subgroup of patients with laparoscopically completed resections showed corresponding results. Conclusion: TEA provides a significant benefit in terms of less analgesic consumption, better postoperative pain relief, and faster recovery of gastrointestinal function in patients undergoing laparoscopic colorectal resectio

Modeling social resilience: Questions, answers, open problems

Resilience denotes the capacity of a system to withstand shocks and its ability to recover from them. We develop a framework to quantify the resilience of highly volatile, non-equilibrium social organizations, such as collectives or collaborating teams. It consists of four steps: (i) \emph{delimitation}, i.e., narrowing down the target systems, (ii) \emph{conceptualization}, .e., identifying how to approach social organizations, (iii) formal \emph{representation} using a combination of agent-based and network models, (iv) \emph{operationalization}, i.e. specifying measures and demonstrating how they enter the calculation of resilience. Our framework quantifies two dimensions of resilience, the \emph{robustness} of social organizations and their \emph{adaptivity}, and combines them in a novel resilience measure. It allows monitoring resilience instantaneously using longitudinal data instead of an ex-post evaluation

Locating Community Smells in Software Development Processes Using Higher-Order Network Centralities

Community smells are negative patterns in software development teams' interactions that impede their ability to successfully create software. Examples are team members working in isolation, lack of communication and collaboration across departments or sub-teams, or areas of the codebase where only a few team members can work on. Current approaches aim to detect community smells by analysing static network representations of software teams' interaction structures. In doing so, they are insufficient to locate community smells within development processes. Extending beyond the capabilities of traditional social network analysis, we show that higher-order network models provide a robust means of revealing such hidden patterns and complex relationships. To this end, we develop a set of centrality measures based on the MOGen higher-order network model and show their effectiveness in predicting influential nodes using five empirical datasets. We then employ these measures for a comprehensive analysis of a product team at the German IT security company genua GmbH, showcasing our method's success in identifying and locating community smells. Specifically, we uncover critical community smells in two areas of the team's development process. Semi-structured interviews with five team members validate our findings: while the team was aware of one community smell and employed measures to address it, it was not aware of the second. This highlights the potential of our approach as a robust tool for identifying and addressing community smells in software development teams. More generally, our work contributes to the social network analysis field with a powerful set of higher-order network centralities that effectively capture community dynamics and indirect relationships.Comment: 48 pages, 19 figures, 4 tables; accepted at Social Network Analysis and Mining (SNAM