P16INK4a as a progression/regression tumour marker in LSIL cervix lesions: Our clinical experience

Purpose of investigation: The aim of this prospective study was the evaluation of low-grade intraepithelial lesion (LSIL) lesions evolvement in woman with evidence of high risk HPV infection and p16 INK4a negative expression. Materials and Methods: 150 women with cytological diagnosis of LSIL were selected to be underwent to three years of follow-up consisting in smear test, colposcopy, and protein p16 INK4a investigation every six months and HPV-test every 12 months. Result: Final follow-up showed 45 cases of spontaneous lesion regression and 42 cases of persistence with absence of protein p16 INK4a in all of them. There were three cases of disease progression to CIN2, two at 18-month follow-up and one at last follow-up. Disease progression was characterized of p16 INK4a expression. Conclusion: p16 INK4a should help to identify which LSIL cases are inclined to the progression of the disease and focalize which patients are eligible for specific treatment

Dispute resolution mechanisms and teacher bargaining outcomes

This study investigates the impact of dispute resolution mechanisms on the wages and hours of public school teachers. The 43-state analysis presents evidence that (1) a permissible right to strike increases teacher wages by 11.5 percent and reduces class hours by 37 minutes per day; (2) a de facto right to strike increases salaries by 5.7 percent and reduces class hours by 44 minutes per day; (3) arbitration availability is associated with a wage effect of 3.6 percent and 70 fewer class minutes per day; and (4) factfinding and voluntary arbitration have no significant influences on outcomes. A direct comparison of the right to strike and the right to arbitrate indicates that a legal right to strike affords teachers greater power to increase the dollar value of their work

“Just” Markets from the Perspective of Catholic Social Teaching

Catholic Social Teaching, economic development, impoverished market segments, inclusive capitalism, justice in the marketplace, marketing and society,

Strategy content and organizational performance: An empirical analysis

This study presents the first empirical test of the proposition that strategy content is a key determinant of organizational performance in the public sector. Strategy content comprises two dimensions: strategic stance (the extent to which an organization is a prospector, defender, or reactor) and strategic actions (the relative emphasis on changes in markets, services, revenues, external relationships, and internal characteristics). Data were drawn from a multiple-informant survey of 119 English local authorities. Measures of strategy content are included in a multivariate model of interauthority variations in performance. The statistical results show that strategy content matters. Organizational performance is positively associated with a prospector stance and negatively with a reactor stance. Furthermore, local authorities that seek new markets for their services are more likely to perform well. These results suggest that measures of strategy content must be included in valid theoretical and empirical models of organizational performance in the public sector.link_to_subscribed_fulltex