12 research outputs found

    Implantation d'un lactarium à HGPRB UCB: les besoins cliniques et scientifique

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    l'exposé reprend l'intérêt du lait maternel et le besoin d'une banque de lait maternel ou lactarium pour assurer l'alimentation optimale du nouveau-né prématur

    Profil épidémiologique des Cardiopathies congénitales à l’Hôpital Provincial Général de Référence de Bukavu: Epidemiological profile of congenital cardiopathy at General provincial hospital of Bukavu

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    Context and objective. Congenital heart disease (CHD) is one of the leading causes of child mortality worldwide, but the data from sub-Saharan Africa remains paradoxically scarce. The objective of this study was to describe the epidemiological profile and outcome of congenital heart disease in a semi-rural setting. Methods. In a retrospective study, the medical records of patients admitted for congenital heart disease between November 2014 and October 2016 were examined at the Provincial General Reference Hospital of Bukavu. The diagnosis of clinically suspected CHD was confirmed by transthoracic Doppler echocardiography (TDE). Results. Of the 7,397 children studied during the study period, 54 had CHD with a hospital frequency of 0.73% and an average age of 3 years old. The female sex was predominant (53.7%) with sex ratio of 1.24/1. Their average age was 3 years old. The most observed CHD were isolated interventricular communication (38.9%), isolated interauricular communication (31.5%), an atrio-ventricular canal (13%) and a tetralogy of Fallot (11.1%). In the absence of an appropriate technical platform, only three children (5.5%) underwent surgery. 6 deaths (11.1%) were deplored. Conclusion: The CHD with a preponderance of interventricular and interauricular communication accounts for nearly one percent of admissions to this semi-rural hospital. Unfortunately, their surgical management of CHD remains a very serious problem, which explains late diagnosis and high mortality. Contexte et objectif. Les cardiopathies congénitales (CC) constituent l’une des causes majeures de mortalité infantile dans le monde, mais les données y relatives en Afrique subsaharienne restent paradoxalement fragmentaires. L’objectif de la présente étude était de décrire le profil épidémiologique et l’issue vitale des cardiopathies congénitales dans un milieu semi rural. Méthodes. Dans une étude documentaire, les dossiers des patients admis pour CC entre novembre 2014 à octobre 2016, ont été colligés, à l’Hôpital Provincial Général de Référence de Bukavu. Le diagnostic de CC suspecté cliniquement, était confirmé par une échocardiographie Doppler transthoracique. Résultats. Des 7397 enfants suivis pendant la période d’étude, 54 avaient une cardiopathie congénitale soit une fréquence hospitalière de 0,73 %. Le sexe féminin était prépondérant (53,7%) avec sexe ratio de 1,24/1. Leur âge moyen était de 3 ans. Les CC les plus observées étaient : la communication interventriculaire isolée (38,9%), une communication inter auriculaire isolée (31,5%), un canal atrio-ventriculaire (13%) et une tétralogie de Fallot (11,1%). Faute de plateau technique approprié, seuls trois enfants (5,5%) ont bénéficié d’une chirurgie. 6 décès (11.1%) ont été déplorés. Conclusion. La CC avec une prépondérance des communications interventriculaire et inter auriculaire rend compte de près d’un pourcent d’admissions dans cet hôpital semi rural. Malheureusement leur prise en charge chirurgicale reste un très sérieux problème responsable du diagnostic tardif et de la forte mortalité

    The critical need for pooled data on coronavirus disease 2019 in African children : an AFREhealth call for action through multicountry research collaboration

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    Globally, there are prevailing knowledge gaps in the epidemiology, clinical manifestations, and outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among children and adolescents; and these gaps are especially wide in African countries. The availability of robust age-disaggregated data is a critical first step in improving knowledge on disease burden and manifestations of coronavirus disease 2019 (COVID-19) among children. Furthermore, it is essential to improve understanding of SARS-CoV-2 interactions with comorbidities and coinfections such as human immunodeficiency virus (HIV), tuberculosis, malaria, sickle cell disease, and malnutrition, which are highly prevalent among children in sub-Saharan Africa. The African Forum for Research and Education in Health (AFREhealth) COVID-19 Research Collaboration on Children and Adolescents is conducting studies across Western, Central, Eastern, and Southern Africa to address existing knowledge gaps. This consortium is expected to generate key evidence to inform clinical practice and public health policy-making for COVID-19 while concurrently addressing other major diseases affecting children in African countries.The US National Institutes of Health (NIH)/ Fogarty International Centre (FIC) to the African Forum for Research and Education in Health (AFREhealth).https://academic.oup.com/cidam2022Paediatrics and Child Healt

    L'asthme ou le spectre asthmatique chez l'enfant

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    ce travail présente les aspects cliniques, investigationnels, thérapeutiques et éducatifs du spectre asthmatique chez l'enfan

    Biomarkers of neonatal stress assessment: A prospective study.

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    INTRODUCTION: Early diagnosis of perinatal asphyxia, the major cause of neonatal mortality and morbidity, might be improved by the detection of neonatal stress biomarkers such as cardiac troponin (CTn)T, CTnI, NT-Terminal-pro-Brain Natriuretic Peptide (NT-pro-BNP), copeptin, and high sensitivity C-reactive protein (hs-CRP). However, reference values in neonates are lacking. The objective of our study was therefore to establish a reference range of these biomarkers in healthy full term newborns and to analyze the influence of delivery mode on their cord blood concentrations. PATIENTS AND METHODS: CTnT, CTnI, NT-pro-BNP, Copeptin and hs-CRP levels were determined in 201 neonates enrolled in this prospective study and correlated to the delivery mode and post-natal outcome. RESULTS: Using the 99th percentile, the upper reference limit in healthy newborns was established for all biomarkers. Neonates born after complicated delivery had significantly higher values of CTnT, CTnI and Copeptin than those born after uncomplicated delivery. In the multiple regression models with CTnT as dependent variable, the delivery mode was the statistically significant independent variable. CONCLUSION: In this study, we established reference values of cord blood concentrations of cardiac stress biomarkers in healthy newborns. We showed that cardiac-related birth stress is dependent on delivery mode

    Nutritional and health status of a cohort of school-age children born to mothers treated for severe acute malnutrition in their childhood in The Democratic Republic of Congo

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    Background Malnutrition is a public health problem, but outside the theoretical framework, little is known about the concrete intergenerational effects of malnutrition. Objective The objective of this study is to compare the nutritional status and health indicators of school children born to mothers who were treated for severe acute malnutrition (SAM). Methodology The study took place in Miti-Murhesa health zone in the Democratic Republic of Congo. This is a cohort study assessing the nutritional and health status of school children born to mothers who had been treated for SAM, based on WHZ or edema, in Lwiro hospital between 1988–2002 compared to children born to mothers who were not exposed to SAM. Stunting and thinness were evaluated by Height for Age Z-score (HAZ) and Body Mass Index by Age criteria (BMIAZ) respectively. On admission, blood samples were taken to assess anemia, HIV serology, hemogram and others biological indicators. Stool’s examinations were conducted by using Olympus optical microscope. Parametric and non-parametric tests were applied to compare the different variables in two groups. Results We identified 106 children aged 5–16 years (103 exposed and 58 unexposed) and we received 83.5% and 91.4% children respectively for anthropometric parameters. The mean of age was 7.9 ± 2.4 year in exposed group and 7.4 ± 2.1 year in unexposed group (p = 0.26). The prevalence of stunting was 68.3% in the exposed group and 67.3% in the unexposed group (p = 0.90). The prevalence of thinness was 12.8% in the exposed group and 9.6% in the unexposed group (p = 0.57). The biological profile (glycemia, urea, creatinine and hemogram) and the prevalence of intestinal parasites were similar in the two groups. Conclusion In this sample, in a malnutrition-endemic area, there was no statistically significant difference in nutrition and health indicators between school children born to mothers exposed to SAM and their community controls.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
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