2,303 research outputs found
File compression using typogenetic computation
Typogenetic algorithms are a break from classical approaches to computation. Based on gene expression and intercellular processes, typo-genetic computation can offer a new approach to the algorithmic problems of system security, data compression and encryption. The method has a potential of much higher compression ratios at the limited computational costs i.e. processing time. This paper presents a formal system based on typogenetics for the purposes of compression. Lossless data compression is an important part of computer science. While the ability to reduce consumption of hard disk space or transmission bandwidth through statistical redundancy has served well in the past, the explosive growth in high quality media content (*.mp3, *.mpg) on the internet in the past few years have highlighted the limitations of traditional statistical techniques for compression. © 2008 IEEE
Novel Observation of Isospin Structure of Short-Range Correlations in Calcium Isotopes
Short-range correlations (SRCs) have been identified as being responsible for the high-momentum tail of the nucleon momentum distribution, n(k). Hard, short-range interactions of nucleon pairs generate the high-momentum tail and imprint a universal character on n(k) for all nuclei at large momentum. Triple coincidence experiments have shown a strong dominance of np pairs, but these measurements involve large final-state interactions. This paper presents the results from Jefferson Lab experiment E08014 which measured inclusive electron scattering cross section from Ca isotopes. By comparing the inclusive cross section from 48Ca to 40Ca in a kinematic region dominated by SRCs we provide a new way to study the isospin structure of SRCs
Compressive Sensing of Signals Generated in Plastic Scintillators in a Novel J-PET Instrument
The J-PET scanner, which allows for single bed imaging of the whole human
body, is currently under development at the Jagiellonian University. The dis-
cussed detector offers improvement of the Time of Flight (TOF) resolution due
to the use of fast plastic scintillators and dedicated electronics allowing for
sam- pling in the voltage domain of signals with durations of few nanoseconds.
In this paper we show that recovery of the whole signal, based on only a few
samples, is possible. In order to do that, we incorporate the training signals
into the Tikhonov regularization framework and we perform the Principal
Component Analysis decomposition, which is well known for its compaction
properties. The method yields a simple closed form analytical solution that
does not require iter- ative processing. Moreover, from the Bayes theory the
properties of regularized solution, especially its covariance matrix, may be
easily derived. This is the key to introduce and prove the formula for
calculations of the signal recovery error. In this paper we show that an
average recovery error is approximately inversely proportional to the number of
acquired samples
Application of the Compress Sensing Theory for Improvement of the TOF Resolution in a Novel J-PET Instrument
Nowadays, in Positron Emission Tomography (PET) systems, a Time of Flight
information is used to improve the image reconstruction process. In Time of
Flight PET (TOF-PET), fast detectors are able to measure the difference in the
arrival time of the two gamma rays, with the precision enabling to shorten
significantly a range along the line-of-response (LOR) where the annihilation
occurred. In the new concept, called J-PET scanner, gamma rays are detected in
plastic scintillators. In a single strip of J-PET system, time values are
obtained by probing signals in the amplitude domain. Owing to Compress Sensing
theory, information about the shape and amplitude of the signals is recovered.
In this paper we demonstrate that based on the acquired signals parameters, a
better signal normalization may be provided in order to improve the TOF
resolution. The procedure was tested using large sample of data registered by a
dedicated detection setup enabling sampling of signals with 50 ps intervals.
Experimental setup provided irradiation of a chosen position in the plastic
scintillator strip with annihilation gamma quanta
Eliashberg-type equations for correlated superconductors
The derivation of the Eliashberg -- type equations for a superconductor with
strong correlations and electron--phonon interaction has been presented. The
proper account of short range Coulomb interactions results in a strongly
anisotropic equations. Possible symmetries of the order parameter include s, p
and d wave. We found the carrier concentration dependence of the coupling
constants corresponding to these symmetries. At low hole doping the d-wave
component is the largest one.Comment: RevTeX, 18 pages, 5 ps figures added at the end of source file, to be
published in Phys.Rev. B, contact: [email protected]
Novel method for hit-position reconstruction using voltage signals in plastic scintillators and its application to Positron Emission Tomography
Currently inorganic scintillator detectors are used in all commercial Time of
Flight Positron Emission Tomograph (TOF-PET) devices. The J-PET collaboration
investigates a possibility of construction of a PET scanner from plastic
scintillators which would allow for single bed imaging of the whole human body.
This paper describes a novel method of hit-position reconstruction based on
sampled signals and an example of an application of the method for a single
module with a 30 cm long plastic strip, read out on both ends by Hamamatsu
R4998 photomultipliers. The sampling scheme to generate a vector with samples
of a PET event waveform with respect to four user-defined amplitudes is
introduced. The experimental setup provides irradiation of a chosen position in
the plastic scintillator strip with an annihilation gamma quanta of energy
511~keV. The statistical test for a multivariate normal (MVN) distribution of
measured vectors at a given position is developed, and it is shown that signals
sampled at four thresholds in a voltage domain are approximately normally
distributed variables. With the presented method of a vector analysis made out
of waveform samples acquired with four thresholds, we obtain a spatial
resolution of about 1 cm and a timing resolution of about 80 p
Safety, tolerability, and impact on allergic inflammation of autologous E.coli autovaccine in the treatment of house dust mite asthma - a prospective open clinical trial
Background: Asthma is increasing worldwide and results from a complex immunological interaction between genetic susceptibility and environmental factors. Autovaccination with E. coli induces a strong TH-1 immune response, thus offering an option for the treatment of allergic diseases. Methods: Prospective open trial on safety, tolerability, and impact on allergic inflammation of an autologous E.coli autovaccine in intermittent or mild persistent house dust mite asthma. Determination of exhaled nitric monoxide (eNO) before and after bronchial mite challenge initially and after nine months of autovaccination. Results: Median eNO increase after autovaccination was significantly smaller (from 27.3 to 33.8 ppb; p=0.334) compared to initial values (from 32.6 to 42.2 ppb; p=0.046) (p=0.034). In nine subjects and a total of 306 injections, we observed 101 episodes of local erythema (33.3%; median of maximal diameter 2.5 cm), 95 episodes of local swelling (31.1%; median of maximal diameter 3 cm), and 27 episodes of local pain (8.8%). Four subjects reported itching at the injection site with a total of 30 episodes (9.8%). We observed no serious adverse events. All organ functions (inclusive electrocardiogramm) and laboratory testing of the blood (clinical chemistry, hematology) and the urine (screening test, B-microglobuline) were within normal limits. Vital signs undulated within the physiological variability. Conclusion: The administration of autologous autovacine for the treatment of house dust mite asthma resulted in a reduction of the eNO increase upon bronchial mite challenge. In nine subjects and 306 injections, only a few mild local reactions and no systemic severe adverse events were observed. EudraCT Nr. 2005-005534-12 ClinicalTrials.gov ID NCT0067720
Molecular Mechanism of Thymidylate Synthase Inhibition by N 4 Hydroxy dCMP in View of Spectrophotometric and Crystallographic Studies
Novel evidence is presented allowing further clarification of the mechanism of the slow binding thymidylate synthase TS inhibition by N4 hydroxy dCMP N4 OH dCMP . Spectrophotometric monitoring documented time and temperature , and N4 OH dCMP dependent TS catalyzed dihydrofolate production, accompanying the mouse enzyme incubation with N4 OH dCMP and N5,10 methylenetetrahydrofolate, known to inactivate the enzyme by the covalent binding of the inhibitor, suggesting the demonstrated reaction to be uncoupled from the pyrimidine C 5 methylation. The latter was in accord with the hypothesis based on the previously presented structure of mouse TS cf. PDB ID 4EZ8 , and with conclusions based on the present structure of the parasitic nematode Trichinella spiralis, both co crystallized with N4 OH dCMP and N5,10 methylenetetrahdrofolate. The crystal structure of the mouse TS N4 OH dCMP complex soaked with N5,10 methylenetetrahydrofolate revealed the reaction to run via a unique imidazolidine ring opening, leaving the one carbon group bound to the N 10 atom, thus too distant from the pyrimidine C 5 atom to enable the electrophilic attack and methylene group transfe
Tevatron-for-LHC Report of the QCD Working Group
The experiments at Run 2 of the Tevatron have each accumulated over 1 inverse
femtobarn of high-transverse momentum data. Such a dataset allows for the first
precision (i.e. comparisons between theory and experiment at the few percent
level) tests of QCD at a hadron collider. While the Large Hadron Collider has
been designed as a discovery machine, basic QCD analyses will still need to be
performed to understand the working environment. The Tevatron-for-LHC workshop
was conceived as a communication link to pass on the expertise of the Tevatron
and to test new analysis ideas coming from the LHC community. The TeV4LHC QCD
Working Group focussed on important aspects of QCD at hadron colliders: jet
definitions, extraction and use of Parton Distribution Functions, the
underlying event, Monte Carlo tunes, and diffractive physics. This report
summarizes some of the results achieved during this workshop.Comment: 156 pages, Tevatron-for-LHC Conference Report of the QCD Working
Grou
Search for eta-mesic 4He in the dd->3He n pi0 and dd->3He p pi- reactions with the WASA-at-COSY facility
The search for 4He-eta bound states was performed with the WASA-at-COSY
facility via the measurement of the excitation function for the dd->3He n pi0
and dd->3He p pi- processes. The beam momentum was varied continuously between
2.127 GeV/c and 2.422 GeV/c, corresponding to the excess energy for the dd->4He
eta reaction ranging from Q=-70 MeV to Q=30 MeV. The luminosity was determined
based on the dd->3He n reaction and quasi-free proton-proton scattering via
dd->pp n_spectator n_spectator reactions. The excitation functions determined
independently for the measured reactions do not reveal a structure which could
be interpreted as a narrow mesic nucleus. Therefore, the upper limits of the
total cross sections for the bound state production and decay in
dd->(4He-eta)_bound->3He n pi0 and dd->(4He-eta)_bound->3He p pi- processes
were determined taking into account the isospin relation between both the
channels considered. The results of the analysis depend on the assumptions of
the N* momentum distribution in the anticipated mesic-4He. Assuming as in the
previous works, that this is identical with the distribution of nucleons bound
with 20 MeV in 4He, we determined that (for the mesic bound state width in the
range from 5 MeV to 50 MeV) the upper limits at 90% confidence level are about
3 nb and about 6 nb for npi0 and ppi- channels, respectively. However, based on
the recent theoretical findings of the N*(1535) momentum distribution in the
N*-3He nucleus bound by 3.6 MeV, we find that the WASA-at-COSY detector
acceptance decreases and hence the corresponding upper limits are 5 nb and 10
nb for npi0 and ppi- channels respectively.Comment: This article will be submitted to JHE
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