131 research outputs found
Dependence of the Nonlinear Photoacoustic Response of Gold Nanoparticles on the Heat-Transfer Process
Photoacoustic (PA) imaging using the nonlinear PA response of gold nanoparticles (GNPs) can effectively attenuate the interference from background noise caused by biomolecules (e.g., hemoglobin), thus offering a highly potential noninvasive biomedical imaging method. However, the mechanism of the nonlinear PA response of GNPs based on the thermal expansion mechanism, especially the effect of heat-transfer ability, still lacks quantitative investigation. Therefore, this work investigated the effect of heat-transfer ability on the nonlinear PA response of GNPs using the critical energy and fluence concept, taking into account the Au@SiO2core-shell nanoparticles (weakened heat transfer) and gold nanochains (enhanced heat transfer). The results showed that the stronger the heat transferability, the smaller the critical energy, indicating that the nonlinear PA response of different nanoparticles cannot be contrasted directly through the critical energy. Moreover, the critical fluence can directly contrast the proportion of nonlinear components in the PA response of different GNPs as governed by the combined effect of heat transferability and photothermal conversion ability
Complications after radical gastrectomy following FOLFOX7 neoadjuvant chemotherapy for gastric cancer
<p>Abstract</p> <p>Background</p> <p>This study assessed the postoperative morbidity and mortality occurring in the first 30 days after radical gastrectomy by comparing gastric cancer patients who did or did not receive the FOLFOX7 regimen of neoadjuvant chemotherapy.</p> <p>Methods</p> <p>We completed a retrospective analysis of 377 patients after their radical gastrectomies were performed in our department between 2005 and 2009. Two groups of patients were studied: the SURG group received surgical treatment immediately after diagnosis; the NACT underwent surgery after 2-6 cycles of neoadjuvant chemotherapy.</p> <p>Results</p> <p>There were 267 patients in the SURG group and 110 patients in the NACT group. The NACT group had more proximal tumours (P = 0.000), more total/proximal gastrectomies (P = 0.000) and longer operative time (P = 0.005) than the SURG group. Morbidity was 10.0% in the NACT patients and 17.2% in the SURG patients (P = 0.075). There were two cases of postoperative death, both in the SURG group (P = 1.000). No changes in complications or mortality rate were observed between the SURG and NACT groups.</p> <p>Conclusion</p> <p>The FOLFOX7 neoadjuvant chemotherapy is not associated with increased postoperative morbidity, indicating that the FOLFOX7 neoadjuvant chemotherapy is a safe choice for the treatment of local advanced gastric cancer.</p
Bridgeness: A Local Index on Edge Significance in Maintaining Global Connectivity
Edges in a network can be divided into two kinds according to their different
roles: some enhance the locality like the ones inside a cluster while others
contribute to the global connectivity like the ones connecting two clusters. A
recent study by Onnela et al uncovered the weak ties effects in mobile
communication. In this article, we provide complementary results on document
networks, that is, the edges connecting less similar nodes in content are more
significant in maintaining the global connectivity. We propose an index named
bridgeness to quantify the edge significance in maintaining connectivity, which
only depends on local information of network topology. We compare the
bridgeness with content similarity and some other structural indices according
to an edge percolation process. Experimental results on document networks show
that the bridgeness outperforms content similarity in characterizing the edge
significance. Furthermore, extensive numerical results on disparate networks
indicate that the bridgeness is also better than some well-known indices on
edge significance, including the Jaccard coefficient, degree product and
betweenness centrality.Comment: 10 pages, 4 figures, 1 tabl
Patchoulene Epoxide Isolated from Patchouli Oil Suppresses Acute Inflammation through Inhibition of NF- κ
Increased GDF9 and BMP15 mRNA levels in cumulus granulosa cells correlate with oocyte maturation, fertilization, and embryo quality in humans
Spin Fluctuations, Interband Coupling, and Unconventional Pairing in Iron-based Superconductors
Based on an effective two-band model and using the fluctuation-exchange
(FLEX) approach, we explore spin fluctuations and unconventional
superconducting pairing in Fe-based layer superconductors. It is elaborated
that one type of interband antiferromagnetic (AF) spin fluctuation stems from
the interband Coulomb repulsion, while the other type of intraband AF spin
fluctuation originates from the intraband Coulomb repulsion. Due to the
Fermi-surface topology, a spin-singlet extended s-wave superconducting state is
more favorable than the nodal -wave state if the interband AF spin
fluctuation is more significant than the intraband one, otherwise vice versa.
It is also revealed that the effective interband coupling plays an important
role in the intraband pairings, which is a distinct feature of the present
two-band system.Comment: 4 pages, 4 figures, to appear in New Journal of Physics focus issue
on iron-based superconductor
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