4 research outputs found
One-Pot Synthesis of Polysubstituted Imidazoles via Sequential Staudinger/aza-Wittig/Ag(I)-Catalyzed Cyclization/Isomerization
A new one-pot preparation of polysubstituted
imidazoles by a Staudinger/aza-Wittig/AgÂ(I)-catalyzed
cyclization/isomerization has been developed. The easily accessible
propargylazide derivatives reacted with triphenylphosphine, isocyanates,
and amines sequentially to produce the fully substituted imidazoles
in good overall yields in the presence of catalytic amount of AgNO<sub>3</sub>/DMAP
Controllable Microfluidic Fabrication of Magnetic Hybrid Microswimmers with Hollow Helical Structures
Controllable
magnetic hybrid microswimmers with hollow helical
structures are fabricated, by a facile strategy based on microfluidic
template synthesis and biosilicification, to achieve enhanced rotation-based
locomotion for cargo transport. The magnetic hybrid microswimmers
are fabricated by first synthesizing Fe<sub>3</sub>O<sub>4</sub>-nanoparticles-containing
helical Ca-alginate microfibers from microfluidics, followed with
biosilicification and controllable dicing to engineer their rigid
hollow helical structures. The microswimmers show hollow helical structures
consisting of a rigid, biocompatible alginate/protamine/silica shell
embedded with Fe<sub>3</sub>O<sub>4</sub> nanoparticles. Their helical
structures can be engineered into open tubular structures or closed
compartmental structures by using microfibers or diced microfibers
as templates for biosilicification. Powered by a simple rotating magnet,
the microswimmers can achieve enhanced rotation-based locomotion and
provide good mechanical strength for supporting cargo for transportation.
This work provides a simple and efficient strategy for fabricating
controllable magnetic hybrid microswimmers with hollow helical structures
to achieve enhanced rotation-based locomotion for cargo transport,
encapsulation, and delivery
Controllable Microfluidic Fabrication of Magnetic Hybrid Microswimmers with Hollow Helical Structures
Controllable
magnetic hybrid microswimmers with hollow helical
structures are fabricated, by a facile strategy based on microfluidic
template synthesis and biosilicification, to achieve enhanced rotation-based
locomotion for cargo transport. The magnetic hybrid microswimmers
are fabricated by first synthesizing Fe<sub>3</sub>O<sub>4</sub>-nanoparticles-containing
helical Ca-alginate microfibers from microfluidics, followed with
biosilicification and controllable dicing to engineer their rigid
hollow helical structures. The microswimmers show hollow helical structures
consisting of a rigid, biocompatible alginate/protamine/silica shell
embedded with Fe<sub>3</sub>O<sub>4</sub> nanoparticles. Their helical
structures can be engineered into open tubular structures or closed
compartmental structures by using microfibers or diced microfibers
as templates for biosilicification. Powered by a simple rotating magnet,
the microswimmers can achieve enhanced rotation-based locomotion and
provide good mechanical strength for supporting cargo for transportation.
This work provides a simple and efficient strategy for fabricating
controllable magnetic hybrid microswimmers with hollow helical structures
to achieve enhanced rotation-based locomotion for cargo transport,
encapsulation, and delivery
Controllable Microfluidic Fabrication of Magnetic Hybrid Microswimmers with Hollow Helical Structures
Controllable
magnetic hybrid microswimmers with hollow helical
structures are fabricated, by a facile strategy based on microfluidic
template synthesis and biosilicification, to achieve enhanced rotation-based
locomotion for cargo transport. The magnetic hybrid microswimmers
are fabricated by first synthesizing Fe<sub>3</sub>O<sub>4</sub>-nanoparticles-containing
helical Ca-alginate microfibers from microfluidics, followed with
biosilicification and controllable dicing to engineer their rigid
hollow helical structures. The microswimmers show hollow helical structures
consisting of a rigid, biocompatible alginate/protamine/silica shell
embedded with Fe<sub>3</sub>O<sub>4</sub> nanoparticles. Their helical
structures can be engineered into open tubular structures or closed
compartmental structures by using microfibers or diced microfibers
as templates for biosilicification. Powered by a simple rotating magnet,
the microswimmers can achieve enhanced rotation-based locomotion and
provide good mechanical strength for supporting cargo for transportation.
This work provides a simple and efficient strategy for fabricating
controllable magnetic hybrid microswimmers with hollow helical structures
to achieve enhanced rotation-based locomotion for cargo transport,
encapsulation, and delivery