More Rigorous Correction of Refraction Effects in Two-media Stereophoto-grammetry

A more rigorous algorithm is presented for correction of refraction effects in two-media stereo photogrammetry. The mid-point of the shortest line segment joining two aerial corresponding rays of a point on an underwater object is used as a photogrammetric intersection point which doesn't exist when the two rays are non-intersecting. As a result, the uncertainty of the intersection point is removed, the positional relationship between the intersection point and the true object point becomes definite, and the refraction correction formula from the intersection point to the true object point can be strictly derived. The bad effect on the refraction correction is firstly analyzed, which caused by that the two rays are non-intersecting. Then the positional relationship between the intersection point and the true object point is studied. After that, the formulas regarding water depth and geodetic coordinates of points on an underwater object are deduced, that is often known as correction of refraction effects. Finally, the algorithm is tested by two experiments using the data of WorldView-2. The results show that the algorithm is suitable for any case in which whether or not the two aerial corresponding rays of an underwater object point are intersecting, and it can significantly improve the measurement accuracy of underwater object's elevation

Tracking Road Centerlines from Remotely Sensed Imagery Using Mean Shift and Kalman Filtering

Road tracking based on template matching is one class of practical methods of road extraction. However, the conventional methods of template matching mainly utilize correlation coefficient as the similarity measure. As a result, these algorithms are sensitive to occlusions caused by vehicles and trees and are unsuitable for road extraction from high-resolution remotely sensed imagery. To address this problem, this paper designs a road center matching algorithm based on mean shift utilizing a robust similarity measure, which overcomes the sensitivity of correlation coefficient matching to occlusions; then Kalman filter is utilized to track road centerlines from high-resolution remotely sensed imagery. Experimental results demonstrate that the proposed method can extract road centerlines from high-resolution remotely sensed imagery accurately and is robust to occlusions caused by vehicles and trees

Association between an indel polymorphism within the distal promoter of EGLN2 and cancer risk: An updated meta‐analysis

Abstract Background The association between a 4‐bp indel polymorphism (rs10680577) within the distal promoter of EGLN2 and cancer risk has been investigated by several case–control studies in recent years, but investigation results were inconsistent. Thus, a systematic assessment of the association was performed based on a literature review and pooled analysis. Methods Two investigators independently retrieved relevant studies from PubMed, Chinese National Knowledge Infrastructure (CNKI), Embase, and Google Scholar. The fixed or random effects model was selected to calculate odds ratios (ORs) with 95% confidence intervals (CIs) based on heterogeneity level. All analyses including heterogeneity assessment, subgroup analysis, sensitivity analysis, and publication bias assessment were performed using RevMan 5.3 software and Stata 12.0 software. Results A total of six relevant studies with 3,406 cases and 5,147 controls were included in the final analysis. The overall pooled analysis showed that EGLN2 rs10680577 polymorphism was significantly associated with cancer risk under all genetic models. However, subgroup analysis based on cancer type showed that the polymorphism was significantly associated with the risk of digestive system cancer under all genetic models, and with the risk of lung cancer under dominant model, heterozygote comparison model, and allele comparison model. Subgroup analysis based on population sources showed a significant association in Chinese population under all genetic models. Conclusion The present result suggests that EGLN2 rs10680577 polymorphism is associated with cancer risk, and may act as a promising predictive biomarker for cancer risk, especially in Chinese population. However, further well‐designed studies are warranted to confirm these results

Establishment and Optimization of Rigorous Geometric Model of Push-broom Camera Using TDI CCD Arranged in an Alternating Pattern

Push-broom cameras using TDI CCD arranged in an alternating pattern are widely carried by typical high-resolution optical satellites in order to obtain high space resolution and enough strip width. For this kind of cameras, several TDI CCD are arranged in an alternating pattern in two lines on the focal plane and push-broom imaging mode is always adopted. Imaging principle and characteristic of this kind of camera is introduced. Exterior parameters of TDI CCD are modeled together based on their same values in any instant of time and an integrated geometric model is finally established. Error compensation methods are designed to remove exterior error and interior error based on this integrated geometric model. A series of tests are designed to verify models and methods proposed in this paper using original image of TH-1 Satellite HR Camera whose detectors are divided into 8 modules arranged in an alternating pattern. As the results, the imaging geometry of this kind of camera can be rigorously described by this integral geometrical model. The positioning accuracy can be obviously improved by our exterior error compensation method, however, different residual error would be remained for different TDI CCD. The positioning accuracy will not be obviously improved while systematic errors of different TDI CCD can be effectively removed by the interior error compensation method. 2 m positioning accuracy in <i>X</i>, <i>Y</i> and <i>Z</i> directions can be achieved and different systematic errors can be removed when both exterior and interior error were compensated. The same accuracy can be achieved in the other scenes when the calculated inner distortion parameters are adopted

Shallow Water Bathymetry through Two-medium Photogrammetry Using High Resolution Satellite Imagery

This paper develops an automated shallow water bathymetry procedure based on two-medium photogrammetry using high resolution satellite multispectral imagery. In this method, near-infrared band were used for sunglint elimination and rational function model (RFM) was applied for raw DEM generation. By extracting the water-land edge and interpolating edge elevation, water surface position could be determined. An approximation refraction correction model, in which all homonymy lights were regarded as intersect to the same observed point, was adopted to correct the vertical offsets. Experimental results indicate that DEM accuracy of satellite two-medium photogrammetry is better than 20% of the average depth under the circumstance of relatively calm water and rich bottom texture

Investigation on the Optical Properties of Micro-LEDs Based on InGaN Quantum Dots Grown by Molecular Beam Epitaxy

InGaN quantum dots (QDs) have attracted significant attention as a promising material for high-efficiency micro-LEDs. In this study, plasma-assisted molecular beam epitaxy (PA-MBE) was used to grow self-assembled InGaN QDs for the fabrication of green micro-LEDs. The InGaN QDs exhibited a high density of over 3.0 × 1010 cm−2, along with good dispersion and uniform size distribution. Micro-LEDs based on QDs with side lengths of the square mesa of 4, 8, 10, and 20 μm were prepared. Attributed to the shielding effect of QDs on the polarized field, luminescence tests indicated that InGaN QDs micro-LEDs exhibited excellent wavelength stability with increasing injection current density. The micro-LEDs with a side length of 8 μm showed a shift of 16.9 nm in the peak of emission wavelength as the injection current increased from 1 A/cm2 to 1000 A/cm2. Furthermore, InGaN QDs micro-LEDs maintained good performance stability with decreasing platform size at low current density. The EQE peak of the 8 μm micro-LEDs is 0.42%, which is 91% of the EQE peak of the 20 µm devices. This phenomenon can be attributed to the confinement effect of QDs on carriers, which is significant for the development of full-color micro-LED displays

E90 subunit vaccine protects mice from Zika virus infection and microcephaly.

Zika virus (ZIKV) became a global threat due to its unprecedented outbreak and its association with congenital malformations such as microcephaly in developing fetuses and neonates. There are currently no effective vaccines or drugs available for the prevention or treatment of ZIKV infection. Although multiple vaccine platforms have been established, their effectiveness in preventing congenital microcephaly has not been addressed. Herein, we tested a subunit vaccine containing the 450 amino acids at the N-terminus of the ZIKV envelope protein (E90) in mouse models for either in utero or neonatal ZIKV infection. In one model, embryos of vaccinated dams were challenged with a contemporary ZIKV strain at embryonic day 13.5. The other model infects neonatal mice from vaccinated dams by direct injection of ZIKV into the developing brains. The vaccine led to a substantial reduction of ZIKV-infected cells measured in the brains of fetal or suckling mice, and successfully prevented the onset of microcephaly compared to unvaccinated controls. Furthermore, E90 could protect mice from ZIKV infection even at 140&nbsp;days post-immunization. This work directly demonstrates that immunization of pregnant mice protects the developing brains of offspring both in utero and in the neonatal period from subsequent ZIKV infection and microcephaly. It also supports the further development of the E90 subunit vaccine towards clinical trials