On NIS-Apriori Based Data Mining in SQL

We have proposed a framework of Rough Non-deterministic Information Analysis (RNIA) for tables with non-deterministic information, and applied RNIA to analyzing tables with uncertainty. We have also developed the RNIA software tool in Prolog and getRNIA in Python, in addition to these two tools we newly consider the RNIA software tool in SQL for handling large size data sets. This paper reports the current state of the prototype named NIS-Apriori in SQL, which will afford us more convenient environment for data analysis.International Joint Conference on Rough Sets　(IJCRS 2016), October 7-11, 2016, Santiago, Chil

Few-femtosecond Electron Beam with THz-frequency Wakefield-driven Compression

We propose and demonstrate a novel method to produce few-femtosecond electron beam with relatively low timing jitter. In this method a relativistic electron beam is compressed from about 150 fs (rms) to about 7 fs (rms, upper limit) with the wakefield at THz frequency produced by a leading drive beam in a dielectric tube. By imprinting the energy chirp in a passive way, we demonstrate through laser-driven THz streaking technique that no additional timing jitter with respect to an external laser is introduced in this bunch compression process, a prominent advantage over the conventional method using radio-frequency bunchers. We expect that this passive bunching technique may enable new opportunities in many ultrashort-beam based advanced applications such as ultrafast electron diffraction and plasma wakefield acceleration.Comment: 5 pages, 4 figure

Resonant Homoclinic Flips Bifurcation in Principal Eigendirections

A codimension-4 homoclinic bifurcation with one orbit flip and one inclination flip at principal eigenvalue direction resonance is considered. By introducing a local active coordinate system in some small neighborhood of homoclinic orbit, we get the Poincaré return map and the bifurcation equation. A detailed investigation produces the number and the existence of 1-homoclinic orbit, 1-periodic orbit, and double 1-periodic orbits. We also locate their bifurcation surfaces in certain regions

DPL: Decoupled Prompt Learning for Vision-Language Models

Prompt learning has emerged as an efficient and effective approach for transferring foundational Vision-Language Models (e.g., CLIP) to downstream tasks. However, current methods tend to overfit to seen categories, thereby limiting their generalization ability for unseen classes. In this paper, we propose a new method, Decoupled Prompt Learning (DPL), which reformulates the attention in prompt learning to alleviate this problem. Specifically, we theoretically investigate the collaborative process between prompts and instances (i.e., image patches/text tokens) by reformulating the original self-attention into four separate sub-processes. Through detailed analysis, we observe that certain sub-processes can be strengthened to bolster robustness and generalizability by some approximation techniques. Furthermore, we introduce language-conditioned textual prompting based on decoupled attention to naturally preserve the generalization of text input. Our approach is flexible for both visual and textual modalities, making it easily extendable to multi-modal prompt learning. By combining the proposed techniques, our approach achieves state-of-the-art performance on three representative benchmarks encompassing 15 image recognition datasets, while maintaining parameter-efficient. Moreover, our DPL does not rely on any auxiliary regularization task or extra training data, further demonstrating its remarkable generalization ability.Comment: 11 pages, 5 figures, 8 table

Fenofibrate suppresses corneal neovascularization by regulating lipid metabolism through PPARα signaling pathway

Purpose: The purpose of this study was to explore the potential underlying mechanism of anti-vascular effects of peroxisome proliferator–activated receptor α (PPARα) agonist fenofibrate against corneal neovascularization (CNV) through the changes of lipid metabolism during CNV.Methods: A suture-induced CNV model was established and the clinical indications were evaluated from day 1 to day 7. Treatments of vehicle and fenofibrate were performed for 5 days after suture and the CNV areas were compared among the groups. The eyeballs were collected for histological analysis, malondialdehyde (MDA) measurement, terminal deoxynucleotidyl transferase 2′-deoxyuridine 5′-triphosphate nick end labeling (TUNEL) staining, western blot, quantitative real-time PCR (qRT-PCR) assays and immunohistochemical (IHC) staining to elucidate pathological changes and the underlying mechanism.Results: Lipi-Green staining and MDA measurement showed that lipid deposition and peroxidation were increased in the CNV cornea while the expression of long-chain acyl-coenzyme A synthetase 1 (ACSL1), carnitine palmitoyltransterase 1A(CPT1A) and medium-chain acyl-coenzyme A dehydrogenase (ACADM), which are key enzymes of fatty acid β-oxidation (FAO) and targeted genes of peroxisome proliferator-activated receptor alpha (PPARα) pathway, were decreased in CNV cornea. Fenofibrate suppressed lipid accumulation and peroxidation damage in the CNV cornea. Fenofibrate upregulated the expression levels of PPARα, ACSL1, CPT1A, and ACADM compared with vehicle group. IHC staining indicated that fenofibrate also decreased the expression of VEGFa, VEGFc, TNFα, IL1β and CD68.Conclusion: Disorder of lipid metabolism may be involved in the formation of suture-induced CNV and fenofibrate played anti-neovascularization and anti-inflammatory roles on cornea by regulating the key enzymes of lipid metabolism and ameliorating lipid peroxidation damage of cornea through PPARα signaling pathway

Optimization of the lightning warning model for distribution network lines based on multiple meteorological factor thresholds

Lightning is one of the frequent natural disasters, which seriously affects the secure and stable operation of the power system, especially the distribution network lines with weak reliability. In order to improve the power supply reliability of the distribution network, higher requirements are put forward for the accuracy of lightning warning. Therefore, this paper establishes a lightning warning model based on comprehensive multi-meteorological factor thresholds and analyzes the meteorological factor data such as atmospheric field strength, echo intensity, echo-top height, and vertical cumulative liquid water content under thunderstorm weather. The threshold value of each factor warning is obtained, and the corresponding threshold weight is calculated by the entropy weight method. According to the weight of each threshold, the comprehensive threshold index of lightning warning is obtained, and the lightning warning is based on this index. A total of 105 lightning data from May to June 2022 in Nanchang city were analyzed as samples. The thresholds of atmospheric field strength, echo intensity, echo-top height, and vertical cumulative liquid water content were 1.2 kV/m, 40 dBZ, 8 km, and 5.2 kg·m−2, respectively. The corresponding weights of each factor were 0.4188, 0.2056, 0.2105, and 0.165, respectively. This model was used to warn a thunderstorm event in July 2022 in Nanchang area. The success rate of the model warning was 0.91, the false alarm rate (FAR) was 0.11, and the critical success index (CSI) was 0.80. Compared with the single-factor threshold lightning warning model, the warning FAR is decreased by 6%, and CSI is increased by 14% while ensuring the high warning success rate

In vitro inhibitory and pro-apoptotic effect of Stellera Chamaejasme L Extract on human lung cancer cell line NCI-H157

AbstractObjectiveTo investigate the inhibitory and pro-apoptotic effect of Stellera Chamaejasme L extract (ESC) in vitro.MethodsESC was first extracted with ethanol, and then washed using a polyamide column with 60% ethanol. ESC was then decompressively recycled and vacuum dried at room temperature to obtain active fractions. Subsequently, the cytotoxic and apoptotic effects of ESC on NCI-H157 human lung cancer cells were determined.ResultsThe results showed that ESC was rich in isomers of Chamaejasminor, neochamaejasmine and Sikokianin. ESC had significant cytotoxicity against NCI-H157 cells, with an IC50 of approximately 18.50 μg · mL−1. ESC caused significant increase in total apoptotic rate, the activity of caspase 3 and 8, and Fas protein expression (P<0.05).ConclusionThe inhibitory effect of ESC on NCI-H157 tumor cells might partly be attributed to its apoptotic induction through activation of the Fas death receptor pathway

Affective and Cognitive Empathy in Pre-teachers With Strong or Weak Professional Identity: An ERP Study

Pain empathy is influenced by a number of factors. However, few studies have examined the effects of strength of professional identity on pain empathy in pre-service teachers. This study used the event-related potential (ERP) technique, which offers a high temporal resolution, to investigate the neurocognitive mechanisms of pain empathy in pre-teachers with strong or weak professional identity. The N110 and P300 components have been shown to reflect an individual’s emotional sharing and cognitive evaluation in pain empathy, respectively. The results of the current study show that pre-teachers with strong professional identity showed a significant difference in N110 amplitudes evoked towards painful and non-painful stimuli; whereas pre-teachers with weak professional identity did not show a significant difference in the amplitudes evoked by the two stimulus types. For the P300 component, pre-teachers with weak professional identity showed a significant difference in the amplitudes evoked towards painful and non-painful stimuli; whereas pre-teachers with strong professional identity did not show a significant difference in the amplitudes evoked by the two stimulus types. Our results indicate that pre-teachers with strong professional identity show a higher level of pain empathy than those with weak professional identity

Synthesis of BiOI-TiO 2

This study was conducted to synthesize a series of nanosized BiOI-TiO2 catalysts to photodegrade Bisphenol A solution. The BiOI-TiO2 nanoparticles were synthesized in the reverse microemulsions, consisting of cyclohexane, Triton X-100, n-hexanol, and aqueous salt solutions. The synthesized particles were characterized by X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET) surface analyzer, Fourier transform-infrared spectroscopy (FT-IR), ultraviolet-visible light (UV-Vis) absorption spectra and transmission electron microscope (TEM). The photodegradation of Bisphenol A (BPA) in aqueous suspension under visible light irradiation was investigated to explore the feasibility of using the photocatalytic method to treat BPA wastewater. The effects of different molar ratios of BiOI to TiO2 on the photocatalytic activity were discussed. The experimental results revealed that the photocatalytic effect of the BiOI-TiO2 particles was superior to the commercial P25 TiO2. The BPA degradation could be approached by a pseudo-first-order rate expression. The observed reaction rate constant (kobs) was related to nanoparticles dosage and initial solution pH

Anti-thrombosis Effects and Mechanisms by Xueshuantong Capsule Under Different Flow Conditions

Xueshuantong capsule (XST) is a patented traditional Chinese medicine used for the prevention and treatment of thrombosis. The molecular mechanism of anti-thrombotic effect of XST was investigated through the cross-talk among the platelets/leukocytes, endothelial cells (ECs), and flow shear stress. The Bioflux 1000 system was used to generate two levels of shear stress conditions: 0.1 and 0.9 Pa. Bioflux Metamorph microscopic imaging system was used to analyze the adhesion cell numbers. Protein expressions were detected by western blotting and flow cytometry. The flow-cytometry results showed that under 0.1 Pa flow, XST decreased ADP induced platelets CD62p surface expression in a concentration-dependent manner. Under 0.9 Pa flow, XST at a concentration of 0.15 g⋅L-1 reduced the platelets activation by 29.5%, and aspirin (ASA) showed no inhibitory effects. XST showed similar efficiency on monocytes adhesion both under 0.1 and 0.9 Pa flow conditions, and the inhibition rate was 30.2 and 28.3%, respectively. Under 0.9 Pa flow, the anti-adhesive effects of XST might be associated with the suppression of VE-cadherin and Cx43 in HUVECs. Blood flow not only acts as a drug transporter, but also exerts its effects to influence the pharmacodynamics of XST. Effects of XST on inhibiting platelets activation and suppressing platelets/leukocytes adhesion to injured ECs are not only concentration-dependent, but also shear stress-dependent. The mechanic forces combined with traditional Chinese medicine may be used as a precise treatment for cardiovascular diseases