178 research outputs found

    Poems

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    辰宵 / Endless night

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    看花 / Looking at flowers

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    狷坐 / Sitting alone

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    闼壤二首 / Melancholy: two poems

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    拊影漫成 / Inspired by scenery

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    春日雜書十首 / from Ten miscellaneous spring day poems

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    Citation analysis of the state owned commercial banks research field based on Histcite

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    Multiple of empirical researchers have found that State-owned commercial banks in various countries have positive effect on the economic growth and financial stability. This paper studies the research literature related to the state owned banks using an online subscription based scientific citation indexing. Wed of Science database is explored for the core data collection for the state-owned banks research literatures and its historical context, using bibliometric analysis software "Histcite" to converts bibliographic collections into generate sequences, transforming the non-numerical data into a graphic format, pointing out the important achievements and development trend of the related fields of state-owned banks

    The Combination of Human Urinary Kallidinogenase and Mild Hypothermia Protects Adult Rats Against Hypoxic-Ischemic Encephalopathy-Induced Injury by Promoting Angiogenesis and Regeneration

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    Objectives: Human Urinary Kallidinogenase (HUK) is a tissue kallikrein that plays neuroprotective role in ischemic conditions via different mechanisms. Mild hypothermia (MH) is another robust neuroprotectant that reduces mortality but does not profoundly ameliorate the neurological outcome in hypoxic-ischemic encephalopathy (HIE) patients. However, whether the combination of HUK and MH can be used as a promising neuroprotective treatment in HIE is unknown. Methods: One-hundred and forty-four adult Wistar rats were randomly divided into five groups: Sham, HIE, HUK, MH and a combination of HUK and MH treatment. The HIE rat model was established by right carotid dissection followed by hypoxia aspiration. The survival curve was created within 7 days, and the neurological severity scores (NSS) were assessed at days 0, 1, 3, and 7. Nissl staining, Terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL), immunofluorescent staining and western blotting were used to evaluate neuronal survival, apoptosis and necrosis, tight-junction proteins Claudin-1 and Zonula occludens-1 (ZO-1), vascular endothelial growth factor (VEGF), doublecortex (DCX), bradykinin receptor B1 (BDKRB1), BDKRB2 and Ki67 staining. Results: The combined treatment rescued all HIE rats from death and had a best survival curve compared to HIE. The Combination also reduced the NSS scores after HIE at days 7, better than HUK or MH alone. The combination of HUK and MH reserved more cells in Nissl staining and inhibited neuronal apoptosis and necrosis as well as significantly attenuated HIE-induced decreases in claudin-1, ZO-1, cyclin D1 and BDKRB1/B2 in comparison to HUK or MH treatment alone. Moreover, the combined treatment increased the expression of VEGF and DCX as well as the number of Ki67-labeled cells. Conclusions: This study demonstrates that both HUK and MH are neuroprotective after HIE insult; however, the combined therapy with HUK and MH enhanced the efficiency and efficacy of either therapy alone in the treatment of HIE, at least partially by promoting angiogenesis and regeneration and rescuing tight-junction loss. The combination of HUK and MH seems to be a feasible and promising clinical strategy to alleviate cerebral injury following HIE insult. Highlights: -The combination of HUK and MH distinctly reduces neurological dysfunction in HIE rats.-HUK enhances the neuroprotective effects of MH in HIE.-MH attenuates tight-junction disruption, upregulates the BDKR B1/2, DCX and cyclin D1.-The combination of MH and HUK enhances the expressions of MH/HUK mediated-BDKR B1/2, DCX, cyclin D1 and Ki67 positive cells

    Morphological Structure, Physicochemical Properties Analysis and Application in Processing Vermicelli of the Kidney Bean Starch Grown in Qianjiang, China

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     The structure, morphology, physicochemical properties and potential use in vermicelli of kidney bean starch, grown in Qianjiang, China, were carried out. Results pointed out that the scanning electron micrographs revealed the presence of kidney or ovoid- to globose-shaped granules and with a diameter ranging from 5 to 50 μm. And the kidney bean starch exhibited an A-type X-ray diffraction pattern. The freeze-thaw stability was poor that the rate of water release was only 41.90%. But the thermal stability and cold stability were good and it showed a C- type Brabender viscosity curve. Besides, the kidney bean vermicelli was prepared by the optimized process. The viscosity and swelling of kidney bean vermicelli were less than mung bean vermicelli, which lead to the acceptable unable to equal to mung bean vermicelli. But considering the price and big cooking loss, weak tensile strength and weak shear strength of other starch vermicelli, the kidney bean starch vermicelli still has important application value
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