Numerical Analysis of the Mechanical Behavior and Failure Mode of Jointed Rock under Uniaxial Tensile Loading

In the field of rock engineering, tensile failure is one of the most significant failure modes due to the presence of joints/fractures. However, due to the limitations of current laboratory testing, it is difficult to carry out direct tensile tests on jointed rock specimens in the laboratory. To study the effect of joints on the mechanical behavior and failure mode of jointed rock specimens, a three-point modeling method that can consider arbitrarily arranged rock joints is deduced and applied to discrete element simulation. The effects of different joint angles (the inclination angle α, rotation angle β, and superimposed angle γ of α and β, where γ is the angle between the joint and horizontal plane), the density (n), and the rate of cutting area (RCA) of the specimen loading surface (LSS) on the tensile strength (σt), elastic modulus in tension (Et), and failure mode of the specimens were analyzed. The results show that the joint angle (considering α, β, and γ) and RCA have a significant effect on the resulting σt and failure mode, while n has a significant effect on Et. The failure mode of the specimen changes from tensile failure along the joint to direct tensile failure of the specimen as γ increases, and the mechanical behavior transitions from unstable to stable. In addition, the main influence of γ on the mechanical behavior of specimens is revealed, and the change process of the failure mode after the cutting of the LSS is analyzed. The present research can be utilized for multiple purposes, including the joint development of surrounding rock and failure dominated by tensile failure in underground engineering, especially for tunnels, roadways, chambers, and so forth

Establishment of a transgene-free iPS cell line (SDQLCHi046-A) from a young patient bearing a HDAC8 mutation and suffering from Cornelia de Lange Syndrome

In this study, peripheral blood mononuclear cells were isolated from a young male patient bearing a histone deacetyl-lase 8 (HDAC8) mutation and suffering from Cornelia de Lange Syndrome verified by clinical and genetic diagnosis. Induced pluripotent stem cells (iPSCs) were established by a non-integrative method, using plasmids carrying OCT4, SOX2, KLF4, BCL-XL and C-MYC. The established iPSCs presented typical pluripotent cells morphology, and expressed pluripotent stem cell markers at the mRNA and protein level. The iPSCs also showed differentiative capacity in vitro, and a normal karyotype. In addition, the established iPSCs still carried the HDAC8 mutation observed in the donor tissue

Parametric Study on the Ground Control Effects of Rock Bolt Parameters under Dynamic and Static Coupling Loads

Dynamic and static coupling loads (DSLs) are one of the most common stress environments in underground engineering. As the depth of a roadway increases over the life of a mine, the static load of the ground stress field increase multiplies, and the cyclic operation at the working face releases a large amount of dynamic energy. Therefore, deep roadways easily induce dynamic disasters during production. In this paper, a deep roadway numerical model was built with FLAC3D to test the deep roadway under DSLs and was simulated with 16 different support designs. The ground stability in each support condition was examined and compared in terms of the ground deformation and scope of failure. The underlying support mechanism was further analyzed with numerical modeling in view of the deformation in the surrounding rock mass induced by variations in the support parameters. The results show that shortening the bolt spacing is an effective measure to control the deformation of surrounding rock whatever DSLs or static load. Under static load, the larger the anchoring length is, the more stable the surrounding rock is. Under DSLs, end grouting length (S = 600 mm) and full grouting length (S = 1800 mm) can effectively control the deformation of surrounding rocks and enhance the stability of surrounding rocks. The results contribute to the design of supports in the field of underground coal mines and provide a basis for determining the reasonable support scheme for roadways

Observations of Forbush Decreases of Cosmic-Ray Electrons and Positrons with the Dark Matter Particle Explorer

The Forbush decrease (FD) represents the rapid decrease of the intensities of charged particles accompanied with the coronal mass ejections or high-speed streams from coronal holes. It has been mainly explored with the ground-based neutron monitor network, which indirectly measures the integrated intensities of all species of cosmic rays by counting secondary neutrons produced from interaction between atmospheric atoms and cosmic rays. The space-based experiments can resolve the species of particles but the energy ranges are limited by the relatively small acceptances except for the most abundant particles like protons and helium. Therefore, the FD of cosmic-ray electrons and positrons have just been investigated by the PAMELA experiment in the low-energy range (<5 GeV) with limited statistics. In this paper, we study the FD event that occurred in 2017 September with the electron and positron data recorded by the Dark Matter Particle Explorer. The evolution of the FDs from 2 GeV to 20 GeV with a time resolution of 6 hr are given. We observe two solar energetic particle events in the time profile of the intensity of cosmic rays, the earlier, and weaker, one has not been shown in the neutron monitor data. Furthermore, both the amplitude and recovery time of fluxes of electrons and positrons show clear energy dependence, which is important in probing the disturbances of the interplanetary environment by the coronal mass ejections

CEPC Technical Design Report -- Accelerator

International audienceThe Circular Electron Positron Collider (CEPC) is a large scientific project initiated and hosted by China, fostered through extensive collaboration with international partners. The complex comprises four accelerators: a 30 GeV Linac, a 1.1 GeV Damping Ring, a Booster capable of achieving energies up to 180 GeV, and a Collider operating at varying energy modes (Z, W, H, and ttbar). The Linac and Damping Ring are situated on the surface, while the Booster and Collider are housed in a 100 km circumference underground tunnel, strategically accommodating future expansion with provisions for a Super Proton Proton Collider (SPPC). The CEPC primarily serves as a Higgs factory. In its baseline design with synchrotron radiation (SR) power of 30 MW per beam, it can achieve a luminosity of 5e34 /cm^2/s^1, resulting in an integrated luminosity of 13 /ab for two interaction points over a decade, producing 2.6 million Higgs bosons. Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons, facilitating precise measurements of Higgs coupling at sub-percent levels, exceeding the precision expected from the HL-LHC by an order of magnitude. This Technical Design Report (TDR) follows the Preliminary Conceptual Design Report (Pre-CDR, 2015) and the Conceptual Design Report (CDR, 2018), comprehensively detailing the machine's layout and performance, physical design and analysis, technical systems design, R&D and prototyping efforts, and associated civil engineering aspects. Additionally, it includes a cost estimate and a preliminary construction timeline, establishing a framework for forthcoming engineering design phase and site selection procedures. Construction is anticipated to begin around 2027-2028, pending government approval, with an estimated duration of 8 years. The commencement of experiments could potentially initiate in the mid-2030s

CEPC Technical Design Report -- Accelerator

International audienceThe Circular Electron Positron Collider (CEPC) is a large scientific project initiated and hosted by China, fostered through extensive collaboration with international partners. The complex comprises four accelerators: a 30 GeV Linac, a 1.1 GeV Damping Ring, a Booster capable of achieving energies up to 180 GeV, and a Collider operating at varying energy modes (Z, W, H, and ttbar). The Linac and Damping Ring are situated on the surface, while the Booster and Collider are housed in a 100 km circumference underground tunnel, strategically accommodating future expansion with provisions for a Super Proton Proton Collider (SPPC). The CEPC primarily serves as a Higgs factory. In its baseline design with synchrotron radiation (SR) power of 30 MW per beam, it can achieve a luminosity of 5e34 /cm^2/s^1, resulting in an integrated luminosity of 13 /ab for two interaction points over a decade, producing 2.6 million Higgs bosons. Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons, facilitating precise measurements of Higgs coupling at sub-percent levels, exceeding the precision expected from the HL-LHC by an order of magnitude. This Technical Design Report (TDR) follows the Preliminary Conceptual Design Report (Pre-CDR, 2015) and the Conceptual Design Report (CDR, 2018), comprehensively detailing the machine's layout and performance, physical design and analysis, technical systems design, R&D and prototyping efforts, and associated civil engineering aspects. Additionally, it includes a cost estimate and a preliminary construction timeline, establishing a framework for forthcoming engineering design phase and site selection procedures. Construction is anticipated to begin around 2027-2028, pending government approval, with an estimated duration of 8 years. The commencement of experiments could potentially initiate in the mid-2030s