Fighting against fast speckle decorrelation for light focusing inside live tissue by photon frequency shifting

Light focusing inside live tissue by digital optical phase conjugation (DOPC) has drawn increasing interest due to its potential biomedical applications in optogenetics, microsurgery, phototherapy, and deep-tissue imaging. However, fast physiological motions in a live animal, including blood flow and respiratory motions, produce undesired photon perturbation and thus inevitably deteriorate the performance of light focusing. Here, we develop a photon-frequency-shifting DOPC method to fight against fast physiological motions by switching the states of a guide star at a distinctive frequency. Therefore, the photons tagged by the guide star are well detected at the specific frequency, separating them from the photons perturbed by fast motions. Light focusing was demonstrated in both phantoms in vitro and mice in vivo with substantially improved focusing contrast. This work puts a new perspective on light focusing inside live tissue and promises wide biomedical applications

Content-Addressable Network for Distributed Simulations

The development of distributed systems, parallel computation technology, and Peer-to-Peer systems facilitates the realization of a distributed interactive world model. Thereby, we can implement a worldwide distributed simulation and virtual community, e.g., city traffic simulation and Massively Multiuser Virtual Environments (MMVE). In this thesis, we present Content-Addressable Network for Simulations (CANS), which is based on CAN. Thus, it incorporates all the advantages of CAN, such as self-organization, scalability, and fault-tolerance. The peers in CANS carry out the simulation for the zone assigned to them, and the zones are allocated in such a way that there is as little communication between the peers as possible. We propose two approaches for reorganizing zone-assignments after peers churn. These approaches are based on the distributed tree structure and prefix code. In comparison to existing approaches, our proposed approaches are more efficient and reliable. Since CANS is used to simulate “city traffic” and MMVE, it requires a low-dimensional key space, i.e., a two-dimensional or three-dimensional key space. Thus, we propose CAN tree routing and zone code routing, both of which adopt long links. CAN tree routing has a hierarchical design that is based on the CAN tree. Each peer equips two long links on average. Zone code routing is based on B*-tree. Each peer equips long links and shares the load evenly. Both of these routing solutions achieve routing hops on average. Consequently, the existing CAN can be optimized to perform simulations efficiently and reliably

On the Acoustoelasticity of Backward Lamb Wave in Prestressed Plate

Backward Lamb waves, which exhibit a group velocity that propagates in the opposite direction to their phase velocity, have recently garnered considerable attention for their potential applications in nondestructive testing. Herein we present a theoretical study on backward Lamb waves in the elastic plate subject to prestresses. We demonstrate that the group velocity of the first antisymmetric backward Lamb wave, A3b, decreases with tensile stress, whereas that of the first symmetric backward Lamb wave, S2b, increases. Notably, the sensitivity of A3b to prestress is approximately ten times greater than that of S2b, with a ~5% change in group velocity observed under a uniaxial stress of 100 MPa in steel. This heightened sensitivity facilitates an inverse method for determining prestress levels in elastic plates by examining variations in the A3b group velocity. We also investigate the acoustoelastic properties of zero-group-velocity (ZGV) points, which demarcate the dispersion curves of forward and backward Lamb waves. Our findings indicate that the ratio of resonance frequencies corresponding to A3b and S2b monotonically decreases as uniaxial stress increases, providing an alternative method for prestress assessment. Lastly, we propose an experimental setup for measuring backward Lamb waves and visualize the generation of A3b using dynamic photoelastic techniques. Our research elucidates the acoustoelastic characteristics of backward Lamb waves and highlights their promising utility for stress measurement in elastic plates

Fighting against fast speckle decorrelation for light focusing inside live tissue by photon frequency shifting

Light focusing inside live tissue by digital optical phase conjugation (DOPC) has drawn increasing interest due to its potential biomedical applications in optogenetics, microsurgery, phototherapy, and deep-tissue imaging. However, fast physiological motions in a live animal, including blood flow and respiratory motions, produce undesired photon perturbation and thus inevitably deteriorate the performance of light focusing. Here, we develop a photon-frequency-shifting DOPC method to fight against fast physiological motions by switching the states of a guide star at a distinctive frequency. Therefore, the photons tagged by the guide star are well detected at the specific frequency, separating them from the photons perturbed by fast motions. Light focusing was demonstrated in both phantoms in vitro and mice in vivo with substantially improved focusing contrast. This work puts a new perspective on light focusing inside live tissue and promises wide biomedical applications

Sintering Preparation of 15 wt% Cr Cast Iron as well as Its Mechanical Properties and Impact Abrasive Wear

15 wt% Cr sintered High Chromium Cast Iron (HCCI) with full density was successfully prepared by Super-solidus Liquid Phase Sintering (SPLS) technique, with water atomized 15 wt% Cr high chromium cast iron powder as initial materials. Its densification behavior and microstructure evolution in SPLS process and mechanical properties were investigated systematically. Additionally, the impact abrasive wear resistance under different impact energies were also analyzed and compared with another sintered HCCI with 20 wt% Cr. The results indicated that sintering temperature has a strong influence on the sintered alloy’s density, hardness, impact toughness and bending strength. The M7C3 type (M is Cr and Fe) carbides were obviously coarsened as temperature increased and their rod-shaped branches were fully developed at the same time, thereby resulting in carbide network formation in the matrix. The reasonable sintering temperature range was 1195–1205 °C, and the optimum mechanical properties had the hardness of 63.9 HRC, bending strength of 2112.65 MPa and impact toughness of 7.92 J/cm2. What is more important impact abrasive wear test results indicated 15 wt% Cr sintered HCCI’s wear resistance could be comparable to 20 wt% Cr sintered HCCI under impact energy 1~3 J/cm2, and it is more cost effective