Syntectonic emplacement of Late Cretaceous mafic dyke swarms in coastal southeastern China: Insights from magnetic fabrics, rock magnetism and field evidence

Magma flow directions for 6 Late Cretaceous mafic dyke swarms exposed in coastal southeastern China (SE China) were analyzed using anisotropy of magnetic susceptibility (AMS) and field evidence. Normal AMS fabrics are predominant. The AMS of the dyke swarms originates mainly from the distribution anisotropy of intersertal magnetite that crystallized during late stage magma flow or after the magma cooled. The AMS fabrics record tectonic stress combined with magma flow. Sub-vertical to vertical magma flow is inferred from symmetrical imbricated magnetic foliations of dyke walls and field evidence for 5 dyke swarms. The inferred (sub-) vertical flow directions also indicate that the magma chambers were probably just beneath the sampled locations. Low anisotropy degree, different orientations of principal AMS axes, and asymmetrical magnetic foliations of normal fabrics oblique to dyke walls indicate syntectonic emplacement of the Late Cretaceous dyke swarms under an extensional tectonic regime caused by Paleo-Pacific plate subduction.This work was financially supported by Zhejiang Provincial Natural Science Foundation of China (Grant LY12D02002). Xiaoqing Pan is further supported by international cooperation and exchange project for doctoral candidates funded by Zhejiang University (Grant 188310- 540615/001)

Research Progress of Organic Corrosion Inhibitors in Metal Corrosion Protection

Metal materials are vulnerable to corrosion in the process of production and service, which often leads to serious disasters, including the decline of the performance of metal components and the shortened service life, and even causes catastrophic accidents and ecological damage. Adding a certain amount of corrosion inhibitors (CIs) to the corrosive medium is a simple, efficient, and economical anti-corrosion method to slow down and restrain the corrosion of metal materials. Organic corrosion inhibitors (OCIs) are considered to have good application prospects and are widely used for surface anti-corrosion of metal materials, as they generally have advantages such as good metal adsorption, low oxidation resistance, good thermal and chemical stability, and green environmental protection. This paper systematically summarized some major OCIs, including alkyl chains, imidazoles, and pyridines, and their structural characteristics, as well as the action mechanism of OCIs. Moreover, this paper discusses some natural compounds used as environmentally friendly CIs and provides a prospect for the development trend of OCIs

Next generation of neurological therapeutics: Native and bioengineered extracellular vesicles derived from stem cells

Extracellular vesicles (EVs)-based cell-free therapy, particularly stem cell-derived extracellular vesicles (SC-EVs), offers new insights into treating a series of neurological disorders and becomes a promising candidate for alternative stem cell regenerative therapy. Currently, SC-EVs are considered direct therapeutic agents by themselves and/or dynamic delivery systems as they have a similar regenerative capacity of stem cells to promote neurogenesis and can easily load many functional small molecules to recipient cells in the central nervous system. Meanwhile, as non-living entities, SC-EVs avoid the uncontrollability and manufacturability limitations of live stem cell products in vivo (e.g., low survival rate, immune response, and tumorigenicity) and in vitro (e.g., restricted sources, complex preparation processes, poor quality control, low storage, shipping instability, and ethical controversy) by strict quality control system. Moreover, SC-EVs can be engineered or designed to enhance further overall yield, increase bioactivity, improve targeting, and extend their half-life. Here, this review provides an overview on the biological properties of SC-EVs, and the current progress in the strategies of native or bioengineered SC-EVs for nerve injury repairing is presented. Then we further summarize the challenges of recent research and perspectives for successful clinical application to advance SC-EVs from bench to bedside in neurological diseases