Bis(1,10-phenanthroline-κ2 N,N′)(sulfato-κ2 O,O′)cobalt(II) butane-2,3-diol monosolvate

In the title compound, [Co(SO4)(C12H8N2)2]·C4H10O2, the Co2+ ion has a distorted octa­hedral coordination environment composed of four N atoms from two chelating 1,10-phenanthroline ligands and two O atoms from an O,O′-bidentate sulfate anion. The dihedral angle between the two chelating N2C2 groups is 83.48 (1)°. The Co2+ ion, the S atom and the mid-point of the central C—C bond of the butane-2,3-diol solvent mol­ecule are situated on twofold rotation axes. The mol­ecules of the complex and the solvent mol­ecules are held together by pairs of symmetry-related O—H⋯O hydrogen bonds with the uncoordinated O atoms of the sulfate ions as acceptors. The solvent mol­ecule is disordered over two sets of sites with site occupancies of 0.40 and 0.60

Efficient callus induction and indirect plant regeneration from various tissues of Jatropha curcas

The Jatropha curcas is considered as an important energy plant due to the fact that its seed contains high oil content. Nowadays focus is being placed on J. curcas callus induction and plant regeneration. In this study, explants epicotyl, hypocotyl, petiole and cotyledon of 8-day-old seedlings of J. curcas were utilized for callus induction on media supplied with 1 mg/L 2,4-dichlorophenoxyacetic acid (2,4-D), naphthyl acetic acid (NAA) or indolebutyric acid (IBA) and 0.1 mg/L kinetin (Kin), and the results demonstrated that the combination of 1 mg/L NAA and 0.1 mg/L Kin was the best medium for callus induction and growth. In addition, induced calli were transferred to regeneration medium containing different combination of auxins and cytokinins, and the data showed that the medium containing 1 mg/L thidiazuron (TDZ) and 1 mg/L Kin combined with 0.1 mg/L IBA was propitious to plant regeneration compared with other combinations.Keywords: Callus induction, indolebutyric acid, Jatropha curcas, kinetin, naphthyl acetic acid, plant regeneration, thidiazuro

Retinoic acid triazole promotes neurotrophin-mediated cell growth and proliferation in nerve cells

In the present study, fluorophenyl retinoic acid triazole, a retinoic acid derivative having more bioavailability compared to the parent retinoic acid was investigated against cell growth and proliferation. The results indicated that fluorophenyl retinoic acid triazole leads to a significant expression of TRK mRNA in time a dependent manner in NB1643 cells. There were about 10-, 14-, and 21-fold induction of expression after 1, 2, and 3 days of treatment, respectively. The results revealed that TRK and TRKB were induced at 6 and 12 hours afterthe treatment respectively and the expression of TRKB was maximum at day 3. Fluorophenyl retinoic acid triazole exerts neurite outgrowth activity by inducing TRKB expression, which is a receptor for brain-derived neurotrophic factor and a protein-tyrosine kinase. Fluorophenyl retinoic acid triazole accumulation generates many small vesiclesin the cell which assembles at the neck of each small prominence and lead to significant morphological changes after 24 hours of treatment