Throughput of Hybrid UAV Networks with Scale-Free Topology

Unmanned Aerial Vehicles (UAVs) hold great potential to support a wide range of applications due to the high maneuverability and flexibility. Compared with single UAV, UAV swarm carries out tasks efficiently in harsh environment, where the network resilience is of vital importance to UAV swarm. The network topology has a fundamental impact on the resilience of UAV network. It is discovered that scale-free network topology, as a topology that exists widely in nature, has the ability to enhance the network resilience. Besides, increasing network throughput can enhance the efficiency of information interaction, improving the network resilience. Facing these facts, this paper studies the throughput of UAV Network with scale-free topology. Introducing the hybrid network structure combining both ad hoc transmission mode and cellular transmission mode into UAV Network, the throughput of UAV Network is improved compared with that of pure ad hoc UAV network. Furthermore, this work also investigates the optimal setting of the hop threshold for the selection of ad hoc or cellular transmission mode. It is discovered that the optimal hop threshold is related with the number of UAVs and the parameters of scale-free topology. This paper may motivate the application of hybrid network structure into UAV Network.Comment: 15 pages, 7 figure

Optimization of Protein-Protein Interaction Measurements for Drug Discovery Using AFM Force Spectroscopy

Increasingly targeted in drug discovery, protein-protein interactions challenge current high throughput screening technologies in the pharmaceutical industry. Developing an effective and efficient method for screening small molecules or compounds is critical to accelerate the discovery of ligands for enzymes, receptors and other pharmaceutical targets. Here, we report developments of methods to increase the signal-to-noise ratio (SNR) for screening protein-protein interactions using atomic force microscopy (AFM) force spectroscopy. We have demonstrated the effectiveness of these developments on detecting the binding process between focal adhesion kinases (FAK) with protein kinase B (Akt1), which is a target for potential cancer drugs. These developments include optimized probe and substrate functionalization processes and redesigned probe-substrate contact regimes. Furthermore, a statistical-based data processing method was developed to enhance the contrast of the experimental data. Collectively, these results demonstrate the potential of the AFM force spectroscopy in automating drug screening with high throughput

Symbol-level Integrated Sensing and Communication enabled Multiple Base Stations Cooperative Sensing

With the support of integrated sensing and communication (ISAC) technology, mobile communication system will integrate the function of wireless sensing, thereby facilitating new intelligent applications such as smart city and intelligent transportation. Due to the limited sensing accuracy and sensing range of single base station (BS), multi-BS cooperative sensing can be applied to realize high-accurate, long-range and continuous sensing, exploiting the specific advantages of large-scale networked mobile communication system. This paper proposes a cooperative sensing method suitable to mobile communication systems, which applies symbol-level sensing information fusion to estimate the location and velocity of target. With the demodulation symbols obtained from the echo signals of multiple BSs, the phase features contained in the demodulation symbols are used in the fusion procedure, which realizes cooperative sensing with the synchronization level of mobile communication system. Compared with the signal-level fusion in the area of distributed aperture coherence-synthetic radars, the requirement of synchronization is much lower. When signal-to-noise ratio (SNR) is -5 dB, it is evaluated that symbol-level multi-BS cooperative sensing effectively improves the accuracy of distance and velocity estimation of target. Compared with single-BS sensing, the accuracy of distance and velocity estimation is improved by 40% and 72%, respectively. Compared with data-level multi-BS cooperative sensing based on maximum likelihood (ML) estimation, the accuracy of location and velocity estimation is improved by 12% and 63%, respectively. This work may provide a guideline for the design of multi-BS cooperative sensing system to exploit the widely deployed networked mobile communication system.Comment: 15 pages, 17 figures, 2 table

Lightweight Structure-aware Transformer Network for VHR Remote Sensing Image Change Detection

Popular Transformer networks have been successfully applied to remote sensing (RS) image change detection (CD) identifications and achieve better results than most convolutional neural networks (CNNs), but they still suffer from two main problems. First, the computational complexity of the Transformer grows quadratically with the increase of image spatial resolution, which is unfavorable to very high-resolution (VHR) RS images. Second, these popular Transformer networks tend to ignore the importance of fine-grained features, which results in poor edge integrity and internal tightness for largely changed objects and leads to the loss of small changed objects. To address the above issues, this Letter proposes a Lightweight Structure-aware Transformer (LSAT) network for RS image CD. The proposed LSAT has two advantages. First, a Cross-dimension Interactive Self-attention (CISA) module with linear complexity is designed to replace the vanilla self-attention in visual Transformer, which effectively reduces the computational complexity while improving the feature representation ability of the proposed LSAT. Second, a Structure-aware Enhancement Module (SAEM) is designed to enhance difference features and edge detail information, which can achieve double enhancement by difference refinement and detail aggregation so as to obtain fine-grained features of bi-temporal RS images. Experimental results show that the proposed LSAT achieves significant improvement in detection accuracy and offers a better tradeoff between accuracy and computational costs than most state-of-the-art CD methods for VHR RS images

Suspension and Measurement of Graphene and Bi2Se3 Atomic Membranes

Coupling high quality, suspended atomic membranes to specialized electrodes enables investigation of many novel phenomena, such as spin or Cooper pair transport in these two dimensional systems. However, many electrode materials are not stable in acids that are used to dissolve underlying substrates. Here we present a versatile and powerful multi-level lithographical technique to suspend atomic membranes, which can be applied to the vast majority of substrate, membrane and electrode materials. Using this technique, we fabricated suspended graphene devices with Al electrodes and mobility of 5500 cm^2/Vs. We also demonstrate, for the first time, fabrication and measurement of a free-standing thin Bi2Se3 membrane, which has low contact resistance to electrodes and a mobility of >~500 cm^2/Vs