Structural Mutual Information and Its Application

Shannon mutual information is an effective method to analyze the information interaction in a point-to-point communication system. However, it cannot solve the problem of channel capacity in graph structure communication system. This problem make it impossible to use traditional mutual information (TMI) to detect the real information and to measure the information embedded in the graph structure. Therefore, measuring the interaction of graph structure and the degree of privacy leakage has become an emerging and challenging issue to be considered. To solve this issue, we propose a novel structural mutual information (SMI) theory based on structure entropy model and the Shannon mutual information theorem, following by the algorithms for solving SMI. The SMI is used to detect the real network structure and measure the degree of private data leakage in the graph structure. Our work expands the channel capacity of Shannon’s second theorem in graph structure, discusses the correlation properties between SMI and TMI, and concludes that SMI satisfies some basic properties, including symmetry, non-negativity, and so on. Finally, theoretical analysis and example demonstration show that the SMI theory is more effective than the traditional privacy measurement methods to measure the information amount embedded in the graph structure and the overall degree of privacy leakage. It provides feasible theoretical support for the privacy protection technology in the graph structure

New Open Cluster Candidates Discovered in the XSTPS-GAC Survey

The Xuyi Schmidt Telescope Photometric Survey of the Galactic Anti-center (XSTPS-GAC) is a photometric sky survey that covers nearly 6 000 deg^2 towards Galactic anti-center in g r i bands. Half of its survey field locates on the Galactic Anti-center disk, which makes XSTPS-GAC highly suitable for searching new open clusters in the GAC region. In this paper, we report new open cluster candidates discovered in this survey, as well as properties of these open cluster candidates, such as age, distance and reddening, derived by isochrone fitting in the color-magnitude diagram (CMD). These open cluster candidates are stellar density peaks detected in the star density maps by applying the method from Koposov et al. (2008). Each candidate is inspected on its true color image composed from XSTPS-GAC three band images. Then its CMD is checked, in order to identify whether the central region stars have a clear isochrone-like trend differing from the background stars. The parameters derived from isochrone fitting for these candidates are mainly based on three band photometry of XSTPS-GAC. Meanwhile, when these new candidates are able to be seen clearly on 2MASS, their parameters are also derived based on 2MASS (J-H, J) CMD. Finally, there are 320 known open clusters rediscovered and 24 new open cluster candidates discovered in this work. Further more, the parameters of these new candidates, as well as another 11 known recovered open clusters, are properly determined for the first time.Comment: 19 pages, 11 figures, 3 tables, accepted for publication in Research in Astronomy and Astrophysic

Improving the Efficacy of Conventional Therapy by Adding Andrographolide Sulfonate in the Treatment of Severe Hand, Foot, and Mouth Disease: A Randomized Controlled Trial

Background. Herb-derived compound andrographolide sulfonate (called Xiyanping injection) recommended control measure for severe hand, foot, and mouth disease (HFMD) by the Ministry of Health (China) during the 2010 epidemic. However, there is a lack of good quality evidence directly comparing the efficacy of Andrographolide Sulfonate combination therapy with conventional therapy. Methods. 230 patients were randomly assigned to 7–10 days of Andrographolide Sulfonate 5–10 mg/Kg/day and conventional therapy, or conventional therapy alone. Results. The major complications occurred less often after Andrographolide Sulfonate (2.6% versus 12.1%; risk difference [RD], 0.94; 95% CI, 0.28–1.61; P=0.006). Median fever clearance times were 96 hours (CI, 80 to 126) for conventional therapy recipients and 48 hours (CI, 36 to 54) for Andrographolide Sulfonate combination-treated patients (χ2=16.57, P<0.001). The two groups did not differ in terms of HFMD-cause mortality (P=1.00) and duration of hospitalization (P=0.70). There was one death in conventional therapy group. No important adverse event was found in Andrographolide Sulfonate combination therapy group. Conclusions. The addition of Andrographolide Sulfonate to conventional therapy reduced the occurrence of major complications, fever clearance time, and the healing time of typical skin or oral mucosa lesions in children with severe HFMD

Altered Posterior Cerebellar Lobule Connectivity With Perigenual Anterior Cingulate Cortex in Women With Primary Dysmenorrhea

Objectives: This study aimed to investigate the potential connectivity mechanism between the cerebellum and anterior cingulate cortex (ACC) and the cerebellar structure in primary dysmenorrhea (PDM).Methods: We applied the spatially unbiased infratentorial template (SUIT) of the cerebellum to obtain anatomical details of cerebellar lobules, upon which the functional connectivity (FC) between the cerebellar lobules and ACC subregions was analyzed and the gray matter (GM) volume of cerebellar lobules was measured by using voxel-based morphometry (VBM) in 35 PDM females and 38 age-matched healthy females. The potential relationship between the altered FC or GM volume and clinical information was also evaluated in PDM females.Results: PDM females showed higher connectivity between the left perigenual ACC (pACC) and lobule vermis_VI, between the left pACC and left lobule IX, and between right pACC and right cerebellar lobule VIIb than did the healthy controls. Compared with healthy controls, no altered GM volume was found in PDM females. No significant correlation was found between altered cerebellum–ACC FC and the clinical variables in the PDM females.Conclusion: PDM females have abnormal posterior cerebellar connectivity with pACC but no abnormal structural changes. ACC–cerebellar circuit disturbances might be involved in the PDM females