Clinical characteristics of ICP and control groups.

<p>The data are expressed as the mean ± S.D., *<i>p</i><0.05 vs. control group, **<i>p</i><0.01 vs. control group. Χ²-test was used to evaluate the comparisons of the rates, *<i>p</i><0.05 vs. control group, **<i>p</i><0.01 vs. control group.</p

Expression of PPARγ and NF-κB protein in placentas from control group and ICP groups.

<p>(A) Western blotting analysis of placental PPARγ and NF-κB protein expression in control, mild ICP and sever ICP groups. (B) Graphical summary of data on the expression of PPARγ protein. (C) Graphical summary of data on the expression of NF-κB protein. The data are expressed as the mean ± S.D., **<i>p</i><0.01 vs. control group.</p

Serum biochemical characteristics of ICP and control groups.

<p>The data are expressed as the mean ± S.D., **p<0.01 vs. control group.</p

Expression of PPARγ andNF-κB mRNA in cultured HTR-8/SVneo cell.

<p>(A) RT-PCR analysis of placental PPARγ and NF-κB mRNA expression in control, mild ICP and sever ICP group. (B) Graphical summary of data on the expression of PPARγ mRNA. (C) Graphical summary of data on the expression of NF-κB mRNA. The data are expressed as the mean ± S.D., ^##<i>p</i><0.01vs. control group, **<i>p</i><0.01 vs. TCA 10 µM/L group.</p

Expression of PPARγ and NF-κB protein in cultured HTR-8/SVneo cell.

<p>(A) Western blotting analysis of placental PPARγ and NF-κB protein expression in control, mild ICP and sever ICP group. (B) Graphical summary of data on the expression of PPARγ mRNA. (C) Graphical summary of data on the expression of NF-κB protein. The data are expressed as the mean ± S.D., ^##<i>p</i><0.01vs. control group, **<i>p</i><0.01 vs. TCA10 µM/L group.</p

Expression of PPARγ and NF-κB mRNA in placentas from control group and ICP groups.

<p>(A) RT-PCR analysis of placental PPARγ and NF-κB mRNAexpression in control, mild ICP and sever ICP groups. (B) Graphical summary of data on the expression of PPARγ mRNA. (C) Graphical summary of data on the expression of NF-κB mRNA. The data are expressed as the mean ± S.D., **<i>p</i><0.01 vs. control group.</p

Serum biochemical characteristics of ICP and control groups.

<p>The data are expressed as the mean ± S.D., **<i>p</i><0.01 vs. control group.</p

PPARγ and NF-κB staining were found in the membrane and cytoplasm of placental trophoblast cell.

<p>×400 (A–C) PPARγ protein expressed in the placenta of control patients, mild ICP patients and severe ICP patients. (D–F) NF-κB protein expressed in the placenta of control patients mild ICP patients and severe ICP patients. PPARγ and NF-κB proteins expression were significantly different in control group and ICP groups.</p