Probing the XYZXYZ states through radiative decays

In this work, we have adopted the spin rearrangement scheme in the heavy quark limit and extensively investigated three classes of the radiative decays: $\mathfrak{M}\to (b\bar{b})+\gamma$, $(b\bar{b})\to \mathfrak{M}+\gamma$, $\mathfrak{M} \to \mathfrak{M}^\prime+\gamma$, corresponding to the electromagnetic transitions between one molecular state and bottomonium, one bottomonium and molecular state, and two molecular states respectively. We also extend the same formalism to study the radiative decays of the molecular states with hidden charm. We have derived some model independent ratios when the initial or final states belong to the same spin flavor multiplet. Future experimental measurement of these ratios will test the molecular picture and explore the underlying structures of the $XYZ$ states.Comment: 21 pages, 10 tables Accepted by Phys.Rev.

Many-qubit network employing cavity QED in a decoherence-free subspace

We propose a many-qubit network with cavity QED by encoding qubits in decoherence-free subspace, based on which we can implement many-logic-qubit conditional gates by means of cavity assisted interaction with single-photon pulses. Our scheme could not only resist collective dephasing errors, but also much reduce the implementational steps compared to conventional methods doing the same job, and we can also complete communications between two arbitrary nodes. We show the details by implementing a three-logic-qubit Toffoli gate, and explore the experimental feasibility and challenge based on currently achievable cavity QED technologies.Comment: 5 pages, 3 figures. to be published in Phys. Rev.

Effect of orthokeratology lenses on teenagers' and children's myopia and its effect on corneal morphology and diopter

AIM: To study the effect of orthokeratology lens on myopia patients and their corneal morphology and diopter. METHODS: Totally 150 cases of myopia children admitted to our hospital from January 2016 to January 2017 were selected and divided into the orthokeratology lens group and the spectacles group according to the wishes of the patients and their families. Visual acuity of all patients was examined before and 1a after treatment. corneal curvature, corneal thickness and diopter were recorded and the complications during treatment was observed as well. RESULTS: The uncorrected visual acuity of orthokeratology lens group was significantly better than that of spectacles group(PPP>0.05). There was no significant difference in diopter between the two groups before treatment(P>0.05); the diopter of orthokeratology lens group was significantly lower than that of spectacles group(PPCONCLUSION: The treatment of myopia with orthokeratology lens has a significant effect, but there are many complications in the patients. Therefore, in the clinical application process, specific precautions should be taken against the factors that may cause complications, so as to make the treatment process safer

Discovery of highly potent HDAC8 PROTACs with anti-tumor activity

Various diseases are deeply associated with aberrations in HDAC8 functions. These aberrations can be assigned to either structural functions or catalytic functions of HDAC8. Therefore, development of HDAC8 degradation inducers might be more promising than HDAC8 inhibitors. We employed the proteolysis targeting chimera (PROTAC) strategy to develop a selective and potent HDAC8 degradation inducer CT-4 with single-digit nanomolar DC50 values and over 95% Dmax in both triple-negative breast cancer MDA-MB-231 cells and T-cell leukemia cells. Notably, CT-4 demonstrated potent anti-migration activity and limited anti-proliferative activity in MDA-MB-231 cells. In contrast, CT-4 effectively induced apototic cell death in Jurkat cells, as assessed by a caspase 3/7 activity assay and flow cytometry. Our findings suggest that the development of HDAC8 degradation inducers holds great potential for the treatment of HDAC8-related diseases

Graphenylene, a unique two-dimensional carbon network with nondelocalized cyclohexatriene units

Over many years chemists have established the general principle that two-dimensional chemical structures constructed with pure sp2-carbon atoms will definitely form an aromatic system with delocalized electron density. However, based on a recently proposed chemical structure, graphenylene, this rule may finally be broken. Herein, we predict the properties of a new two-dimensional sp2- carbon network known as graphenylene, which is the first example of a non-delocalized sp2-carbon structure composed of cyclohexatriene units with two quite distinct C–C bonds within a C6 ring. In addition, theoretical calculations demonstrate that graphenylene has periodic pores of 3.2 Å in diameter and is a semiconductor with a narrow direct band gap, making it promising for various applications, such as electronic devices and efficient hydrogen separation. This study provides a new perspective on carbon allotropes, leading to a better understanding of [N]phenylene based organic frameworks, as well as clarifying the relationship between benzene and cyclohexatriene

A Transmissive X-ray Polarimeter Design For Hard X-ray Focusing Telescopes

The X-ray Timing and Polarization (XTP) is a mission concept for a future space borne X-ray observatory and is currently selected for early phase study. We present a new design of X-ray polarimeter based on the time projection gas chamber. The polarimeter, placed above the focal plane, has an additional rear window that allows hard X-rays to penetrate (a transmission of nearly 80% at 6 keV) through it and reach the detector on the focal plane. Such a design is to compensate the low detection efficiency of gas detectors, at a low cost of sensitivity, and can maximize the science return of multilayer hard X-ray telescopes without the risk of moving focal plane instruments. The sensitivity in terms of minimum detectable polarization, based on current instrument configuration, is expected to be 3% for a 1mCrab source given an observing time of 10^5 s. We present preliminary test results, including photoelectron tracks and modulation curves, using a test chamber and polarized X-ray sources in the lab