Additional file 1 of Causal relationship between blood metabolites and risk of five infections: a Mendelian randomization study

Additional file 1: Supplement Figure 1. Scatterplot for the significant Mendelian randomization (MR) association (FDR < 0.05) between metabolites and 4 types of infection phenotypes (sepsis, pneumonia, URTI, and UTI). SNP, single nucleotide polymorphism; URTI, upper respiratory tract infection; UTI, urinary tract infection. Supplement Figure 2. Forest plots for the Mendelian randomization (MR) leave-one-out analysis of the significant inverse variance weighted (IVW) estimates. URTI, upper respiratory tract infection; UTI, urinary tract infection. Supplement Figure 3. Meta‑analysis of the causal associations between metabolites and 4 types of infection phenotypes (sepsis, pneumonia, URTI, and UTI). OR, odds ratio; CI, confidence interval; URTI, upper respiratory tract infection; UTI, urinary tract infection