A Review of Research on Aging Families: Emerging Issues

Against the background of the demographic shifts of population aging, increased immigration, and growing ethno‐cultural diversity in Canada, it is important that we gain a better understanding of the needs of aging families. To date, family gerontologists have begun producing research on aging families to better understand how their needs can be met. In order to assess the state of the literature on aging families, we conducted a literature search (2009‐ 2014) of eleven top, peer‐reviewed journals. This literature was then assessed, revealing five prevalent themes: (1) structural diversity in aging families, (2) family relationships in later life, (3) caregiving and intergenerational transfers, (4) living arrangements of aging families, and (5) partnerships in later life. This article synthesizes the research of each theme and each of their subsequent sub‐themes. Lastly, the article concludes with some suggestions for future directions in research which were revealed through the literature review

Stable Real-Time Feedback Control of a Pneumatic Soft Robot

Soft actuators offer compliant and safe interaction with an unstructured environment compared to their rigid counterparts. However, control of these systems is often challenging because they are inherently under-actuated, have infinite degrees of freedom (DoF), and their mechanical properties can change by unknown external loads. Existing works mainly relied on discretization and reduction, suffering from either low accuracy or high computational cost for real-time control purposes. Recently, we presented an infinite-dimensional feedback controller for soft manipulators modeled by partial differential equations (PDEs) based on the Cosserat rod theory. In this study, we examine how to implement this controller in real-time using only a limited number of actuators. To do so, we formulate a convex quadratic programming problem that tunes the feedback gains of the controller in real time such that it becomes realizable by the actuators. We evaluated the controller's performance through experiments on a physical soft robot capable of planar motions and show that the actual controller implemented by the finite-dimensional actuators still preserves the stabilizing property of the desired infinite-dimensional controller. This research fills the gap between the infinite-dimensional control design and finite-dimensional actuation in practice and suggests a promising direction for exploring PDE-based control design for soft robots

Internet searches for opioids predict future emergency department heroin admissions.

BackgroundFor a number of fiscal and practical reasons, data on heroin use have been of poor quality, which has hampered the ability to halt the growing epidemic. Internet search data, such as those made available by Google Trends, have been used as a low-cost, real-time data source for monitoring and predicting a variety of public health outcomes. We aimed to determine whether data on opioid-related internet searches might predict future heroin-related admissions to emergency departments (ED).MethodsAcross nine metropolitan statistical areas (MSAs) in the United States, we obtained data on Google searches for prescription and non-prescription opioids, as well as Substance Abuse and Mental Health Services Administration (SAMHSA) data on heroin-related ED visits from 2004 to 2011. A linear mixed model assessed the relationship between opioid-related Internet searches and following year heroin-related visits, controlling for MSA GINI index and total number of ED visits.ResultsThe best-fitting model explained 72% of the variance in heroin-related ED visits. The final model included the search keywords "Avinza," "Brown Sugar," "China White," "Codeine," "Kadian," "Methadone," and "Oxymorphone." We found regional differences in where and how people searched for opioid-related information.ConclusionsInternet search-based modeling should be explored as a new source of insights for predicting heroin-related admissions. In geographic regions where no current heroin-related data exist, Internet search modeling might be a particularly valuable and inexpensive tool for estimating changing heroin use trends. We discuss the immediate implications for using this approach to assist in managing opioid-related morbidity and mortality in the United States

1-Methyl-2,6-cis-distyrylpiperidine

The complete molecule of the title compound, C22H25N, is generated by crystallographic mirror symmetry, with two C atoms and the N atom lying on the mirror plane. The central ring adopts a chair conformation and the dihedral angle between the aromatic rings is 56.69 (4)°

(2S,6S)-1-Methyl-2,6-trans-distyryl­piperidinium chloride

In the crystal structure of the title compound, C22H26N+·Cl−, the piperidine ring is in a chair conformation and the two styryl groups are in axial and equatorial positions. The mol­ecule has a hydrogen bond between the NH group and the chloride anion

Both adhE and a Separate NADPH-Dependent Alcohol Dehydrogenase Gene, adhA, Are Necessary for High Ethanol Production in Thermoanaerobacterium saccharolyticum

Thermoanaerobacterium saccharolyticum has been engineered to produce ethanol at ∼90% theoretical yield and titer of 70 g/L. Its ethanol-producing ability has drawn attention to its metabolic pathways, which could potentially be transferred to other organisms of interest. Here we report that the iron-containing AdhA is important for ethanol production in the high-ethanol strain of T. saccharolyticum (LL1049). A single-gene deletion of adhA in LL1049 reduced ethanol production by ∼50%, whereas multiple gene deletions of all annotated alcohol dehydrogenases except adhA and adhE did not affect ethanol production. Deletion of adhA in wild-type T. saccharolyticum reduced NADPH-linked ADH activity (acetaldehyde-reducing) by 93%

Structural and electronic properties of Eu- and Pd-doped ZnO

Doping ZnO with rare earth and 4d transition elements is a popular technique to manipulate the optical properties of ZnO systems. These systems may also possess intrinsic ferromagnetism due to their magnetic moment borne on 4f and 4d electrons. In this work, the structural, electronic, and magnetic properties of Eu- and Pd-doped ZnO were investigated by the ab initio density functional theory methods based on generalized gradient approximation. The relative stability of incorporation sites of the doped elements in the ZnO host lattice was studied. The ground state properties, equilibrium bond lengths, and band structures of both the ZnO:Eu and ZnO:Pd systems were also investigated. The total and partial densities of electron states were also determined for both systems. It was found that in the ZnO:Eu system, ambient ferromagnetism can be induced by introducing Zn interstitial which leads to a carrier-mediated ferromagnetism while the ZnO:Pd system possesses no ferromagnetism